Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-25T15:18:12.333Z Has data issue: false hasContentIssue false
  • English
  • Français

Response surface analyses of the effects of dietary protein, fat and carbohydrate on feeding and growth pattern in mice from weaning to maturity

Published online by Cambridge University Press:  02 September 2010

M. Toyomizu ,
S. Kimura  and
Y. Tomita
M. Toyomizu
Affiliation:
Animal Nutrition, Department of Animal Science, Kagoshima University, Korimoto, Kagoshima, Japan 890
S. Kimura
Affiliation:
Animal Nutrition, Department of Animal Science, Kagoshima University, Korimoto, Kagoshima, Japan 890
Y. Tomita
Affiliation:
Animal Nutrition, Department of Animal Science, Kagoshima University, Korimoto, Kagoshima, Japan 890
Get access

Abstract

Responses of gross energy intake and body weight of mice from weaning to maturity to dietary composition of energy-yielding nutrients were studied. Twenty-four groups of ddY male mice were fed for 70 days purified diets with a range of 0·08 to 0·75 protein, 0 to 0·92 fat and 0 to 0·92 carbohydrate concentration, calculated on a gross energy basis. Food intake and body weight data in each group were analysed by non-linear regression to obtain values of the parameters in the feeding and growth equation of Parks (1982). Prediction equations for these parameters were obtained with mixture model forms as a function of dietary protein, fat and carbohydrate. These equations for the parameters were then used to construct the response surfaces of body weight and growth rate at a given time on a triangular graph. The response surfaces of body weight at any time were convex, peak positions of which shifted from 043 protein and 0·29 fat at 10 days to 0·36 protein and 0·52 fat at 70 days. The configuration of response surfaces of growth rate (dW/dt) to the three components depends on feeding periods and at the longer periods of feeding the convex configuration of the surfaces became planar. The response surfaces of food efficiency (dW/dF) at any age were almost parallel to those of dW/dt, whereas a parallelism was observed between response surfaces of dW/dt and dF/dt only in young animals. These results suggested that the responses of body weight in young animals to dietary composition of energy-yielding nutrients depended on those of daily energy intake as well as food efficiency, but that those in older animals were affected by food efficiency only.

Keywords

body weightenergy intakegrowth ratemathematical modelsmice
Type
Research Article
Information
Animal Production , Volume 56 , Issue 2 , April 1993 , pp. 251 - 259
Copyright
Copyright © British Society of Animal Science 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baldwin, R. L. and Black, J. L. 1979. Simulation of the effects of nutritional and physiological status on the growth of mammalian tissues: description and evaluation of a computer program. Commonwealth Scientific and Industrial Research Organisation, Animal Research Laboratories technical paper no. 6, pp. 1–35.Google Scholar
Batschelet, E. 1979. Introduction to mathematics for life scientists, pp. 234–300. Springer-Verlag, New York.CrossRefGoogle Scholar
Brody, S. 1964. Bioenergetics and growth, pp. 76–99. Hafner, New York.Google Scholar
Cornell, J. A. 1981. Experiments with mixtures: designs, models, and the analysis of mixture data, pp. 16–64. John Wiley, New York.Google Scholar
Forbes, J. M. 1986. The voluntary food intake of farm animals, pp. 86–113. Butterworth, London.CrossRefGoogle Scholar
Harper, A. E. 1959. Amino acid balance and imbalance. I. Dietary level of protein and amino acid imbalance. Journal of Nutrition 68: 405–418.CrossRefGoogle ScholarPubMed
Oltjen, J. W., Bywater, A. C. and Baldwin, R. L. 1985. Simulation of normal protein accretion in rats. Journal of Nutrition 115:45–52.CrossRefGoogle ScholarPubMed
Oscai, L. B., Brown, M. M. and Miller, W. C. 1984. Effect of dietary fat on food intake, growth and body composition in rats. Growth 48: 415–424.Google ScholarPubMed
Owen, J. B. and Ridgman, W. J. 1968. Further studies of the effect of dietary energy content on the voluntary intake of pigs. Animal Production 10: 85–91.CrossRefGoogle Scholar
Parks, J. R. 1970. Growth curves and the physiology of growth. I. Animals. American journal Physiology 219: 833–836.CrossRefGoogle ScholarPubMed
Parks, J. R. 1973. Diet space and response surfaces. Journal of Theoretical Biology 42: 349–358.CrossRefGoogle ScholarPubMed
Parks, J. R. 1982. A theory of feeding and growth of animals, pp. 52–69. Springer-Verlag, New York.CrossRefGoogle Scholar
Robinson, D. W., Holmes, J. H. G. and Bayley, H. S. 1974. Food intake regulation in pigs. 1. The relationship between dietary protein concentration, food intake and plasma amino acids. British Veterinary journal 130: 361–365.CrossRefGoogle Scholar
Rogers, Q. R. and Harper, A. E. 1965. Amino acid diets and maximal growth in the rat. Journal of Nutrition 87: 267–273.CrossRefGoogle ScholarPubMed
Statistical Analysis System Institute 1985. SAS user's guide: statistics. Version 5 edition. SAS Institute Inc., Cary, NC.Google Scholar
Toyomizu, M., Akiba, Y., Horiguchi, M. and Matsumoto, T. 1982. Multiple regression and response surface analyses of the effects of dietary protein, fat and carbohydrate on the body protein and fat gain in growing chicks. Journal of Nutrition 112: 886–896.CrossRefGoogle ScholarPubMed
Toyomizu, M., Hayashi, K., Yamashita, K. and Tomita, Y. 1988. Response surface analyses of the effects of dietary protein on feeding and growth patterns in mice from weaning to maturity. Journal of Nutrition 118: 86–92.CrossRefGoogle ScholarPubMed
Toyomizu, M., Kimura, S., Hayashi, K. and Tomita, Y. 1989. Body protein and energy accretion in response to dietary protein level in mice from weaning to maturity. Journal of Nutrition: 119: 1028–1033.CrossRefGoogle ScholarPubMed
Toyomizu, M., Matsukubo, M., Hayashi, K. and Tomita, Y. 1991. Response surface analyses of the effects of dietary fat on feeding and growth pattern in mice from weaning to maturity. Animal Production 52: 207–214.Google Scholar
Webster, A. J. F. 1980. The energetic efficiency of growth. Livestock Production Science 7: 243–252.CrossRefGoogle Scholar
Yanase, A. 1978, User's guide: program library for perspective-TPERSP-, pp. 13–14. Computer Center, Tohoku University, Japan.Google Scholar