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Performance of pigs with or without the intestinal receptor for Escherichia coli K88

Published online by Cambridge University Press:  02 September 2010

Inger Edfors-Lilja
Affiliation:
Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, S-750 07 Uppsala, Sweden
H. Petersson
Affiliation:
Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, S-750 07 Uppsala, Sweden
B. Gahne
Affiliation:
Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, S-750 07 Uppsala, Sweden
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Abstract

The adhesion of Escherichia (E.) coli K88ac to epithelial cells of the small intestine was studied after slaughter in 564 crossbred pigs (Swedish Landrace x Swedish Yorkshire). E.coli K88ac adhered to epithelial cells obtained from different parts of the small intestine in 40·8% of the pigs studied. Performance data indicated that presence of the receptor resulted in poorer daily gain during the 1st weeks of life, but that it had a beneficial influence on daily lean growth during the fattening period (24 to 100 kg live weight).

Type
Research Article
Copyright
Copyright © British Society of Animal Science 1986

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References

REFERENCES

Anderson, Martha J., Whitehead, J. S. and Kim, Y. S. 1980. Interaction of Escherichia coli K88 antigen with porcine intestinal brush border membranes. Infect. Immun. 29: 897901.CrossRefGoogle ScholarPubMed
Arbuthnott, J. P. and Smyth, C. J. 1979. Bacterial adhesion in host-pathogen interactions in animals. In Adhesion of Microorganisms to Surfaces (ed. Ellwood, D. C., Melling, J. and Rutter, P.), pp. 165198. Society for General Microbiology, London.Google Scholar
Bulsma, I. G. W., De Nijs, A., Van Der MEER, C. and Frik, J. F. 1982. Different pig phenotypes affect adherence of Escherichia coli to jejunal brush borders by K88ab, K88ac, or K88ad antigen. Infect. Immun. 37: 891894.Google Scholar
Chappuis, J. P., Duval-Iflah, Yvonne, Ollivier, L. and Legault, C. 1984. Escherichia coli K88 adhesion: A comparison of Chinese and Large White piglets. Genet. Sel. Evol. 16: 385390.CrossRefGoogle ScholarPubMed
Gibbons, R. A., Jones, G. W. and Sellwood, R. 1975. An attempt to identify the intestinal receptor for the K88 adhesion by means of a haemagglutination inhibition test using glycoproteins and fractions from sow colostrum. J. Gen. Microbiol. 86: 228240CrossRefGoogle Scholar
Gibbons, R. A., Sellwood, R., Burrows, M. and Hunter, P. A. 1977. Inheritance of resistance to neonatal E. coli diarrhoea in the pig: examination of the genetic system. Theor. appl. Genet. 51: 6570.CrossRefGoogle ScholarPubMed
Grondalen, T. and Vangen, O. 1975. Osteochondrosis and arthrosis in pigs. V. A comparison of the incidence in three different lines of the Norwegian Landrace breed. Ada. vet. scand. 15: 6179.CrossRefGoogle Scholar
Jones, G. W. and Rutter, J. M. 1972. Role of the K88 antigen in the pathogenesis of neonatal diarrhoea caused by Escherichia coli in piglets. Infect. Immun. 6: 918927.CrossRefGoogle ScholarPubMed
Kearns, M. J. and Gibbons, R. A. 1979. The possible nature of the pig intestinal receptor for the K88 antigen of Escherichia coli. FEMS Microbiol. Lett. 6: 165168.CrossRefGoogle Scholar
Lundeheim, N. 1985. Genetic analysis of osteochondrosis and leg weakness in the Swedish pig progeny testing scheme. Proc. 36th A. Meet. Eur. Ass. Anim. Prod., Halkidiki, Greece, p. 320.Google Scholar
Morris, J. A., Thorns, C. J., Scott, A. C., Sojka, W. J. and Wells, G. A. 1982. Adhesion in vitro and in vivo associated with an adhesive antigen (F41) produced by a K99 mutant of the reference strain Escherichia coli B41. Infect. Immun. 36: 11461153.CrossRefGoogle ScholarPubMed
Nagy, B., Moon, H. W. and Isaacson, R. E. 1977. Colonization of porcine intestine by enterotoxigenic Escherichia coli: Selection of piliated forms in vivo, adhesion of piliated forms to epithelial cells in vitro, and incidence of a pilus antigen among porcine enteropathogenic E. coli. Infect. Immun. 16: 344352.CrossRefGoogle ScholarPubMed
Newby, T. J. and Stokes, C. R. 1984. The intestinal immune system and oral vaccination. Vet. Immun. Immunopath. 6: 67105.CrossRefGoogle ScholarPubMed
Petersson, H. 1986. Studies on genotype-nutrient interactions in swine. Rep., Dep. Anim. Breed. Genet., Swedish Univ. Agric. Sci., Uppsala, No. 61. In press.Google Scholar
Rapacz, J. and Hasler-Rapacz, Judith. 1984. Polymorphism in swine small intestine enterocyte receptors mediating adhesion of different enteropathogenic Escherichia coli K88+ antigens to brush borders. Abstr. 19th Int. Soc. Anim. Bloodgroup Res. Conf., Gottingen, p. 59.Google Scholar
Reiland, S., Ordell, Nina, Lundeheim, N. and Olsson, S. E. 1978. Heredity of osteochondrosis, body constitution and leg weakness in the pig. A correlative investigation using progeny testing. Ada radiol., Suppl. 358, pp. 123137.Google Scholar
Rutter, J. M., Burrows, M. R., Sellwood, R. and Gibbons, R. A. 1975. A genetic basis for resistance to enteric disease caused by E. coli. Nature, Lond. 257: 135136.CrossRefGoogle ScholarPubMed
Sellwood, R. 1979. Escherichia coli diarrhoea in pigs with or without the K88 receptor. Vet. Rec. 105: 228230.CrossRefGoogle ScholarPubMed
Sellwood, R. 1980. The interaction of the K88 antigen with porcine intestinal epithelial cell brush borders. Biochim. biophys. Ada 632: 326335.CrossRefGoogle ScholarPubMed
Sellwood, R., Gibbons, R. A., Jones, G. W. and Rutter, J. M. 1975. Adhesion of enteropathogenic Escherichia coli to pig intestinal brush borders: the existence of two pig phenotypes. J. med. Microbiol. 8: 405411.CrossRefGoogle ScholarPubMed
Smith, H. and Huggins, M. B. 1978. The influence of plasmid-determined and other characteristics of enteropathogenic Escherichia coli on their ability to proliferate in the alimentary tracts of piglets, calves and lambs. J. med. Microbiol. 11: 471492.CrossRefGoogle ScholarPubMed
Smith, H. W. and Linggood, Margaret A. 1971. Observations on the pathogenic properties of the K88, Hly and Ent plasmids of E. coli with particular reference to porcine diarrhoea. J. med. Microbiol. 4: 467485.CrossRefGoogle ScholarPubMed
Snodgrass, D. R., Chandler, D. S. and Makin, T. J. 1981. Inheritance of Escherichia coli K88 adhesion in pigs: identification of nonadhesive phenotypes in a commercial herd. Vet. Rec. 109: 461463.CrossRefGoogle Scholar
Staley, T. E. and Wilson, I. B. 1983. Soluble pig intestinal cell membrane components with affinities for E. coli K88' antigen. Mol. Cell. Biochem. 52: 177189.CrossRefGoogle ScholarPubMed
Statistical Analysis System. 1982. SAS User's Guide. Statistical Analysis Systems Institute, Cary, NC.Google Scholar
Stirm, S., Ørskov, F., Ørksov, Ida and Birchandersen, A. 1967. Episome-carried surface antigen K88 of Escherichia coli. III. Morphology. J. Baa. 93: 740748.Google ScholarPubMed
Svendsen, J., Larsen, J. L. and Bille, N. 1974. Outbreaks of post weaning Escherichia coli diarrhoea in pigs. Nord. VetMed. 26: 314322.Google ScholarPubMed
Svendsen, J., Riising, H. J. and Christensen, S. 1977. Studies on the pathogenesis of enteric E.coli infections in weaned pigs: bacteriological and immunoflourescent studies. Nord. VetMed. 29: 212220.Google Scholar
Walters, J. R. and Sellwood, R. 1982. Aspects of genetic resistance to K88 E. coli in pigs. Proc. 2nd Wld Congr. Genet. Appl. Livest. Prod. Vol. VIII, pp. 362367. Editorial Garsi, Madrid.Google Scholar
Walters, J. R. and Sellwood, R. 1984. Observations on the performance of pigs genetically resistant to K88 E. coli. Proc. 8th International Pig Veterinary Society Congr., Ghent, p. 74.Google Scholar