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Introgression of genes responsible for disease resistance in a cattle population selected for production: genetic and economic consequences

Published online by Cambridge University Press:  18 August 2016

E.H. van der Waaij  and
J.A.M. van Arendonk
E.H. van der Waaij
Affiliation:
Animal Breeding and Genetics Group, Wageningen Institute of Animal Sciences, Wageningen University, PO Box 338, 6700 AH Wageningen, The Netherlands
J.A.M. van Arendonk
Affiliation:
Animal Breeding and Genetics Group, Wageningen Institute of Animal Sciences, Wageningen University, PO Box 338, 6700 AH Wageningen, The Netherlands
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Abstract

The genetic and economic consequences of introgression of either one or two genes that explain the complete between-breed difference for disease resistance between donor and recipient breeds were investigated. Four backcross strategies (0, 1, 3 or 7 generations of backcrossing) were compared for four initial breed differences (0·1, 1, 2·5 and 5 phenotypic s.d.) when female reproductive capacity was either high (10 offspring) or lower (four offspring). Selection in donor and recipient populations was for production using a selection index. Genetic comparison was based on production level between the hybrid population, after fixation of the disease resistance alleles, and the donor population. Tor a large initial breed difference and high female reproductive capacity, application of seven generations of backcrossing resulted in the largest genetic difference between donor and hybrid populations. Introgression of one or two genes made no difference to the genetic results. From an economic point of view, optimal number of generations depends on the number of genes involved in the introgression, on the female reproductive capacity and ön the initial breed difference. Seven generations of backcrossing in most cases are too many and none to three generations of backcrossing often is more optimal. Introgression of two genes is economically less attractive, especially in case of low female reproduction capacity.

Keywords

cattledisease resistanceintrogressionproduction
Type
Breeding and genetics
Information
Animal Science , Volume 70 , Issue 2 , April 2000 , pp. 207 - 220
Copyright
Copyright © British Society of Animal Science 2000

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