Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-19T23:16:31.218Z Has data issue: false hasContentIssue false

The influence of different doses of oestradiol benzoate on the attainment of puberty in the gilt

Published online by Cambridge University Press:  02 September 2010

H. Yang
Affiliation:
Department of Animal Physiology and Nutrition, University of Leeds, Leeds LS2 9JT
R. G. Rodway
Affiliation:
Department of Animal Physiology and Nutrition, University of Leeds, Leeds LS2 9JT
M. A. Varley
Affiliation:
Department of Animal Physiology and Nutrition, University of Leeds, Leeds LS2 9JT
Get access

Abstract

Forty Large White ♂ × (Large White (f × Landrace ♀) pre-pubertal gilts were used to study the influence of five different doses of parenteral oestradiol benzoate (OB) on the attainment of puberty. Five gilts from eight litters were treated at 140 days of age with either 5, 10, 15, 20 or 25 μg OB per kg body weight (BW). The doses were split equally into three bolus injections given on consecutive days. Daily boar contact commenced on the day that the first oestrogen injection was given and continued until the gilts were mated. All gilts were slaughtered at either 20 days post coitum or at 235 days of age for those gilts not exhibiting a second oestrus.

The numbers of gilts which ovulated within 10 days after OB injection were: 5/8, 7/8, 8/8, 6/8 and 5/8 for treatments 5 ng/kg BW through to 25 fig/kg BW, respectively. These differences were not significant (P > 0·05). The duration of behavioural oestrus after OB injection was positively correlated to the dose of oestrogen administered (r = 0·98, P < 0·01). There were no significant differences in age at puberty between treatments, and no significant differences were found in the subsequent reproductive performance.

Type
Research Article
Copyright
Copyright © British Society of Animal Science 1987

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Deligeorgis, S. G., English, P. R., Lodge, G. A. and Foxcroft, G. R. 1984. Comparison of two methods for evaluating reproductive development in prepubertal gilts. Animal Production 38: 283291.Google Scholar
Dial, G. D., Dial, O. K., Bevier, G. W., Glenn, S. D. and Dzuik, P. J. 1983. Estrous behavior and circadian discharge of luteinizing hormone in the prepubertal gilt in response to exogenous estrogen. Biology of Reproduction 29: 10471056.CrossRefGoogle ScholarPubMed
Ford, J. J. and Christenson, R. K. 1980. Synthetic glucocorticoid inhibition of estrus in estrogen-treated ovariectomized gilts: relationship to progesterone action. Journal of Animal Science 51: Suppl. 1, p. 89 (Abstr.).Google Scholar
Hughes, P. E. and Cole, D. J. A. 1975. Reproduction in the gilt 1. The influence of age and weight at puberty on ovulation rate and embryo survival in the gilt. Animal Production 21: 183189.Google Scholar
Hughes, P. E. and Cole, D. J. A. 1978. Reproduction in the gilt 3. The effect of exogenous oestrogen on the attainment of puberty and subsequent reproductive performance. Animal Production 27: 1120.Google Scholar
Hughes, P. E. and Varley, M. A. 1980. Reproduction in the Pig. Butterworths, London.Google Scholar
Nowak, R. and Rodway, R. G. 1985. Effect of intravaginal implants of melatonin on the onset of ovarian activity in adult and prepubertal ewes. Journal of Reproduction and Fertility 74: 287293.CrossRefGoogle ScholarPubMed
Parlow, A. F. 1964. Differential action of small doses of oestradiol on gonadotrophins in the rat. Endocrinology 75: 18.CrossRefGoogle ScholarPubMed
Paterson, A. M. 1982. The controlled induction of puberty. In Control of Pig Reproduction (ed. Cole, D. J. A. and Foxcroft, G. R.), pp. 139159. Butterworths, London.CrossRefGoogle Scholar
Paterson, A. M. and Day, B. N. 1980. The effect of estradiol benzoate on estrus and ovulation in prepubertal gilts. Journal of Animal Science 51: Suppl. 1, p. 88 (Abstr.).Google Scholar
Paterson, A. M., Pearce, G. P., Foxcroft, G. R. and Reed, H. C. B. 1984. Reproductive performance of gilts induced into puberty with oestradiol benzoate or a combination of pregnant mare's serum gonadotrophin and human chorionic gonadotrophin. Animal Production 38: 121128.Google Scholar
Ramirez, V. D. and Sawyer, C. H. 1965. Advancement of puberty in the female rat by oestrogen. Endocrinology 76: 1158–1168.CrossRefGoogle Scholar
Stickney, K. 1982. The physiology of oestrogen-induced puberty in the gilt. Ph.D Thesis, University of Nottingham.Google Scholar