Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-27T19:33:38.999Z Has data issue: false hasContentIssue false

Growth and carcass composition of pre-pubertal dairy heifers treated with bovine growth hormone

Published online by Cambridge University Press:  02 September 2010

L. D. Sandles
Affiliation:
Ellinbank Dairy Research Institute, Warragul, 3820, Australia
C. J. Peel
Affiliation:
Ellinbank Dairy Research Institute, Warragul, 3820, Australia
Get access

Abstract

The effects of long-term administration of exogenous growth hormone (GH) on growth and carcass composition of pasture-fed, pre-pubertal dairy heifers were examined. Purified bovine GH (specific activity, 0·78 i.u. per mg) was administered daily for 21 weeks (0·6 mg GH per kg M0·75) to one member of each of 12 sets of twins. GH administration resulted in a significantly higher growth rate (0·58 kg/ day) compared with the control group (0·54 kg/day) and produced a heavier carcass (75·6 kg v. 69·5 kg). However, this production gain did not persist when GH treatment ceased. Plasma metabolite concentrations and carcass composition were not affected by GH treatment. GH tended to increase slightly the voluntary intake of freshly cut herbage dry matter (3·5 kg/day v. 3·7 kg/day; P < 0·05), but had no effect on food conversion efficiency. Serum somatomedin levels were not significantly increased by GH during week 13 of treatment. This experiment indicates that pre-pubertal heifers chronically treated with GH will increase their food intake to sustain an increased rate of growth. However, the production gains made over the treatment period were transient and within 5 weeks of the cessation of GH treatment there was no difference in the live weight of the two groups.

Type
Research Article
Copyright
Copyright © British Society of Animal Science 1987

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Armstrong, D. T. and Hansel, W. 1956. The effect of age and plane of nutrition on growth hormone and thyrotropic hormon e content of pituitary glands of Holstein heifers. Journal of Animal Science 15: 640649.CrossRefGoogle Scholar
Bittner, D. L. and McClhary, M. L. 1963. The cupric-phenanthroline chelate in the determination of monosaccharides in whole blood. American Journal of Clinical Pathology 11: 423 (Abstr.).Google Scholar
Brown, M. E. and Boston, M. S. 1961. Ultra micro sugar determinations using 2,9-dimethyl-l, 10-phenanthroline hydrochloride (Neocuprione). Diabetes 10: 6062.CrossRefGoogle Scholar
Brumby, P. J. 1959. The influence of growth hormone on growth in young cattle. New Zealand Journal of Agricultural Research 2: 683689.CrossRefGoogle Scholar
Car, M., Znidar, A. and Filipan, T. 1967. An effect of the treatment of young steers with STH (growth hormone) upon nitrogen retention in intensive feeding. Veterinarski archiv Zagreb 37: 173184.Google Scholar
Daughaday, W. H., Herington, A. C. and Phillips, L. S. 1976. The regulation of growth by endocrines. Annual Review of Physiology 37: 211244.CrossRefGoogle Scholar
Davis, S. L., Garrigus, U. S. and Hinds, F. C. 1970. Metabolic effects of growth hormone and diethylstilbestrol in lambs. II. Effects of daily ovine growth hormone injections on plasma metabolites and nitrogen-retention in fed lambs. Journal of Animal Science 30: 236–240.Google ScholarPubMed
Evans, H. M. and Simpson, M. E. 1931. Hormones of the anterior hypophysis. American Journal of Physiology 53: 511–546.Google Scholar
Franklin, R. C, Rennie, G. C., Burger, H. G. and Cameron, D. P. 1976. A bioassay for NSILA-S in individual serum samples and its relationship to somatotropin. Journal of Clinical Endocrinology and Metabolism 43: 11641169.CrossRefGoogle ScholarPubMed
Grfenbaum, A. L. 1953. Changes in body composition and respiratory quotient of adult female rats treated with purified growth hormone. Biochemical Journal 54: 400407.CrossRefGoogle Scholar
Herington, A. C, Jacobs, L. S. and Daughaday, W. H. 1974. Radioreceptor and radioimmunoassay quantitation of human growth hormone in acromegalic serum: overestimation by immunoassay and systematic differences between antiscra. Journal of Clinical Endrocrinology and Metabolism 39: 256261.Google Scholar
Lund-Larsen, T. R., Sundby, A., Kruse, V. and Velle, W. 1977. Relation between growth rate, serum somatometlin and plasma testosterone in young bulls. Journal of Animal Science 44: 189194.CrossRefGoogle ScholarPubMed
MacHlin, L. J. 1972. Effect of porcine growth hormone on growth and carcass composition of the pig. Journal of Animal Science 35: 794800.CrossRefGoogle ScholarPubMed
MacHlin, L. J. 1976. Role of growth hormone in improving animal production. In Anabolic Agents in Animal Production, FAOIWHO Symposium, pp. 4352. Theime, Stuttgart.Google Scholar
Moseley, W. M., Krabill, L. F. and Olsen, R. F. 1982. Effect of bovine growth hormone administered in various patterns on nitrogen metabolism in the Holstein steer. Journal of Animal Science 55: 10621070.CrossRefGoogle ScholarPubMed
Smuir, L. A., Wien, S., Duquette, P. F., Rickes, E. L. and Cordes, E. H. 1983. Effects of exogenous growth hormone and diethylstilbestrol on growth and carcass composition of growing lambs. Journal of Animal Science 56: 13151323.Google Scholar
Peel, C. J., Bauman, D. E., Gorewit, R. C. and Sniffen, C. J. 1981. Effect of exogenous growth hormone on lactational performance in high yielding dairy cows. Journal of Nutrition 111: 16621671.CrossRefGoogle ScholarPubMed
Peel, C. J., Sandies, L. D., Ouelch, K. J. and Herington, A. C. 1985. The effects of long-term administration of bovine growth hormone on the lactational performance of identical-twin dairy cows. Animal Production 41: 135142.Google Scholar
Reichert, L. E. Jr, 1975. Purification of anterior pituitary hormones (ovine, bovine, rat and rabbit). In Methods in Enzymology. Vol. 37. Hormone Action. Part B. Peptide Hormones(ed. O'Malley, B. W. and J. G. Hardman), pp. 360380. Academic Press, New York.Google Scholar
Rosen, H. 1957. A modified ninhydrin colorimetric analysis for amino acids Archives of Biochemistry and Biophysics 67: 1015.CrossRefGoogle ScholarPubMed
Tannenbaum, G. S. 1980. Evidence for autoregulation of growth hormone secretion via the central nervous system. Endocrinology 107: 21172120.CrossRefGoogle ScholarPubMed
Wagner, J. F. and Veenhuizen, E. L. 1978. Growth performance, carcass composition and plasma hormone levels in wether lambs when treated with growth hormone and thyroprotein. Journal of Animal Science 47: Suppl. 1, p. 397 (Abstr.).Google Scholar
Wallace, A. L. C. and Bassett, J. M. 1966. Effect of sheep growth hormone on plasma insulin concentration i n sheep. Metabolism 15: 9597.CrossRefGoogle Scholar
Wallace, A. L. C. and Bassett, J. M. 1970. Plasma growth hormone concentrations in sheep measured by radioimmunoassay. Journal of Endocrinology 47: 2136.CrossRefGoogle ScholarPubMed
Wheatley, I. S., Wallace, A. L. C. and Bassett, J. M. 1966. Metabolic effects of ovine growth hormone n i sheep. Journal of Endocrinology 35: 341353.CrossRefGoogle Scholar
Wynn, P. C, Wallace, A. L. C. and Annison, E. F. 1979. Effects of growth hormone on wool growth and nitrogen balance in ewes. Proceedings of the Nutrition Society of Australia 4: 133 (Abstr.).Google Scholar
Znidar, A. 1976. Effect of the application of growth hormone on the gain and feed consumption of Simmental bulls. Poljoprivredna Znanstrena Smotra 37: 171186.Google Scholar