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Evaluation of a slow-release form of recombinantly derived bovine somatotropin in dairy cattle

Published online by Cambridge University Press:  02 September 2010

J. Kim ,
R. C. Campling  and
J. I. D. Wilkinson
J. Kim
Affiliation:
Wye College, University of London, Ashford, Kent TN25 5AH
R. C. Campling
Affiliation:
Wye College, University of London, Ashford, Kent TN25 5AH
J. I. D. Wilkinson
Affiliation:
Lilly Research Centre Ltd, Windlesham, Surrey GU20 6PH
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Abstract

Dairy cattle were injected at intervals of 4 weeks with recombinantly derived bovine somatotropin (bST) i n a slow-release form (somidobove, Lilly Research Centre Ltd, Windlesham, Surrey), to examine the effect on milk production. In the first experiment with 38 autumn-calving animals in a randomized-block design, treatment lasted for 28 weeks and a control and three doses of bST: 320 (low), 640 (medium) and 960 (high) mg were compared. Over the 28 weeks the mean daily milk yields were: control 23·4, low 23·4, medium 25·4 and high 25·4 (s.e.d. 1·17) kg. Milk composition was not affected by bST. In experiment 2 with 40 autumn-calving animals, the medium dose of bST was used for 24 weeks in animals given two levels of concentrate in a factorial design. On average there was a non-significant increase in daily milk yield of 1·3 kg in the bST-treated cattle; there was no interaction between bST and level of concentrate. There were no effects of bST on milk composition. Changes in live weight and body condition of the cattle and their food intake were measured. It was concluded that the trends toward higher milk yields were supported initially at the expense of live weignt and possibly later by increased food intake. In a third experiment 10 grazing cows were given three consecutive doses of 640 mg bST and 10 similar cows acted as controls. There were no significant effects of bST on milk production and food intake. Reasons for the low responses in milk production compared with several recent American and European experiments may possibly be the pattern of use of the slow-release form of bST and the low content of dry matter in the maize silages which restricted forage intake and response in milk production.

Keywords

dairy cattlesomatotropin
Type
Research Article
Information
Animal Production , Volume 52 , Issue 1 , February 1991 , pp. 49 - 56
Copyright
Copyright © British Society of Animal Science 1991

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References

REFERENCES

Bauman, D. E. 1987. Bovine somatotropin in lactation: impact on management and feeding. Proceedings of the 1987 Cornell Nutrition Conference, pp. 23–29.Google Scholar
Burton, J. H., Mcbride, B. W., Bateman, K., Macleod, G. K. and Eggert, R. G. 1987. Recombinant bovine somatotropin: effects on production and reproduction in lactating cows. Journal of Dairy Science 70: Suppl. 1, p. 175 (Abstr.).Google Scholar
Chalupa, W., Hausman, B., Kronfeld, D. S., Kensigner, R. S., Mccarthy, R. D. and Rock, D. W. 1984. Responses of lactating cows to exogenous growth hormone and dietary sodium bicarbonate. I. Production. Journal of Dairy Science 67: Suppl. 1, p. 107 (Abstr.).Google Scholar
Chilliard, Y. 1988. Long-term effects of recombinant bovine somatotropin (rBST) on dairy cow performance. Annales do Zootechnie 37: 159–180.Google Scholar
Elvinger, F., Head, H. H., Wilcox, C. J., Natzke, R. P. and Eggert, R. G. 1988. Effects of administration of bovine somatotropin on milk yield and composition. Journal of Dairy Science 71: 1515–1525.CrossRefGoogle ScholarPubMed
Kim, J., Campling, R. C. and Tarrant, M. E. 1989. Evaluation of slow-release form of recombinantly derived bovine somatotropin in dairy cattle. Animal Production 48: 623 (Abstr.).Google Scholar
Kirchgessner, M., Schwab, W. and Muller, H. L. 1989. Effect of bovine growth hormone on energy metabolism of lactating cows in long-term administration. In Energy Metabolism of Farm Animals (ed. Honing, Y. Van der and Close, W. H.), pp. 143–146. Pudoc, Wageningen.Google Scholar
Mcguffey, R. K., Green, H. B. and Basson, R. P. 1987. Performance of Holsteins given bovine somatotropin in a sustained delivery vehicle. Journal of Dairy Science 70: Suppl. 1, p. 177 (Abstr.).Google Scholar
Mcguffey, R. K., Green, H. B. and Basson, R. P. 1988. Protein nutrition of the somatotropin-treated cow in early lactation. Journal of Dairy Science 71: Suppl. 1, p. 120 (Abstr.).Google Scholar
Meyer, R. M., Mcguffey, R. K., Basson, R. P., Rakes, A. H., Harrison, J. H., Emery, R. S., Muller, L. D. and Block, E. 1988. The effect of somidobove sustained release injection on the lactation performance of dairy cattle. Journal of Dairy Science 71: Suppl. 1, p. 207 (Abstr.).Google Scholar
Mulvany, P. 1977. Dairy cow condition scoring. National Institute for Research in Dairying, Paper No. 4468.Google Scholar
Oldenbroek, J. K., Garssen, G. J., Forbes, A. B. and Jonker, L. J. 1989. The effect of treatment of dairy cows of different breeds with recombinantly derived bovine somatotropin in a sustained delivery vehicle. Livestock Production Science 21: 13–34.Google Scholar
Peel, C. J. and Bauman, D. E. 1987. Somatotropin and lactation. Journal of Dairy Science 70: 474–486.Google Scholar
Peel, C. J., Sandles, L. D., Quelch, K. J. and Herington, A. C. 1985. The effects of long-term administration of bovine growth hormone on the lactational performance of identical-twin dairy cows. Animal Production 41: 135–142.Google Scholar
Phipps, R. K. 1988. The use of prolonged release bovine somatotropin in milk production. Bulletin No. 228, International Dairy Federation, Brussels.Google Scholar
Sonderholm, C. G., Otterby, D. E., Linn, J. G., Ehle, F. R., Wheaton, J. E., Hansen, W. P. and Annexstad, R. J. 1988. Effects of recombinant bovine somatotropin on milk production, body composition and physiological parameters. Journal of Dairy Science 71: 355–365.CrossRefGoogle Scholar
Thomas, C., Johnsson, I. D., Fisher, W. J., Bloomfield, G. A. and Morant, S. V. 1987. The effect of recombinant bovine somatotropin on milk production, reproduction and health of dairy cows. Animal Production 44: 460 (Abstr.).Google Scholar