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The effects of selection for high and low body weight on the proportion and distribution of fat in mice

Published online by Cambridge University Press:  02 September 2010

P. Allen  and
J. C. McCarthy
P. Allen
Affiliation:
Faculty of Agriculture, University College Dublin, Belfield, Dublin 4, Ireland
J. C. McCarthy
Affiliation:
Faculty of Agriculture, University College Dublin, Belfield, Dublin 4, Ireland
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Abstract

The growth of adipose tissue was investigated in lines of mice selected for high and low body weight at 5 and 10 weeks of age, by dissecting and weighing individual fat depots from mice aged 5, 7·5, 10 and 15 weeks. At fixed ages most depots were heavier in the High lines and lighter in the Low lines. Depots grew at different rates and the rate of total fat deposition relative to gain in body weight was greater in High than in Low lines. At about 20g live weight High and Low lines had similar proportions of total fat; at lower weights the High lines were relatively leaner. These correlated effects of selection were more pronounced in the faster growing depots of the kidneys and gonads. In consequence, the High an d Low lines had different fat distributions at fixed ages, at fixed body weights and at fixed weights of fat.

Type
Research Article
Information
Animal Production , Volume 31 , Issue 1 , August 1980 , pp. 1 - 11
Copyright
Copyright © British Society of Animal Science 1980

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References

REFERENCES

Allen, P. 1977. Experimental studies of genetical variation in the pattern of fat deposition of mice and sheep. Ph.D. Thesis, Natn. Univ. Ireland, Dublin.Google Scholar
Butterfield, R. M. 1965. The relationship of carcase measurements and dissection data to beef carcase composition. Res. vet. Sci. 6: 24–32.CrossRefGoogle ScholarPubMed
Clarke, J. N. 1969. Studies on the genetic control of growth in mice. Ph.D. Thesis, Univ. Edinburgh.Google Scholar
Donald, H. P., Read, J. L. and Russell, W. S. 1970. Influence of litter size and breed of sire on carcass weight and quality of lambs. Anim. Prod. 12: 281–290.Google Scholar
Falconer, D. S. 1973. Replicated selection for body weight in mice. Genet. Res. 22: 291–321.CrossRefGoogle ScholarPubMed
Fowler, Ruth E. 1958. The growth and carcass composition of strains of mice selected for large and small body size. J. agri. Sci., Camb. 51: 137–148.CrossRefGoogle Scholar
Harvey, W. R. 1960. Least squares analysis of data with unequal subclass numbers. U.S. Dep. Agric. Publ. No. ARS-20-8.Google Scholar
Hayes, J. F. and McCarthy, J. C. 1976. The effects of selection at different ages for high and low body weight on the pattern of fat deposition in mice. Genet. Res. 27: 389–403.CrossRefGoogle ScholarPubMed
Huxley, J. S. 1932. Problems of Relative Growth. Methuen, London.Google Scholar
Kempster, A. J. and Cuthbertson, A. 1977. A survey of the carcass characteristics of the main types of British lamb. Anim. Prod. 25: 165–179.Google Scholar
Kempster, A. J., Cuthbertson, A. and Harrington, G. 1976. Fat distribution in steer carcasses of different breed s and crosses. 1. Distribution between depots. Anim. Prod. 23: 25–34.Google Scholar
McCarthy, J. C. 1967. The effects of in-breeding on the components of litter size in mice. Genet. Res. 10: 73–80.CrossRefGoogle Scholar
McCarthy, J. C. 1979. Normal variation in body fat and its inheritance. Animal Models of Obesity (ed. Festing, M. F. W.), pp. 1–14. Macmillan, London.Google Scholar
McCarthy, J. C. and Barker, H. 1979. The effects of selection for different combinations of weights at two ages on the growth curve of mice. Theor. appl. Genet. 55: 57–64.CrossRefGoogle ScholarPubMed
McCarthy, J. C. and Doolittle, D. P. 1977. Effects of selection for independent changes in two highly correlated body weight traits of mice. Genet. Res. 29: 133–145.CrossRefGoogle ScholarPubMed
McPhee, C. P. and Neill, A. R. 1976. Changes in the body composition of mice selected for high and low eight week weight. Theor. appl. Genet. 47: 21–26.CrossRefGoogle ScholarPubMed
Martin, A. H., Fredeen, H. T., Weiss, G. M. and Carson, R. B. 1972. Distribution and composition of porcine carcass fat. J. Anim. Sci. 35: 534–541.CrossRefGoogle Scholar
Pomeroy, R. W. and Williams, D. R. 1974. The partition of fat in the bovine carcass. Proc. Br. Soc. Anim. Prod. {New Series) 3: 85 (Abstr.)Google Scholar
Richmond, R. J. and Berg, R. T. 1971. Tissue development in swine as influenced by liveweight, breed, sex and ration. Can. J. Anim. Sci. 51: 31–39.CrossRefGoogle Scholar
Roberts, R. C. 1979. Side effects of selection for growth in laboratory animals. Livest. Prod. Sci. 6: 93–104.CrossRefGoogle Scholar
Seebeck, R. M. 1968. A dissection study of the distribution of tissues in lamb carcasses. Proc. Aust. Soc. Anim. Prod. 7: 297–302.Google Scholar
Snedecor, G. W. and Cochran, W. G. 1967. Statistical Methods. 6th ed.Iowa State University Press, Ames, la.Google Scholar