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The effect of previous body condition on appetite and associated insulin profiles in sheep

Published online by Cambridge University Press:  02 September 2010

A. M. Sibbald  and
S. M. Rhind
A. M. Sibbald
Affiliation:
Macaulay Land Use Research Institute, Craigiebuckler, Aberdeen AB15 8QH
S. M. Rhind
Affiliation:
Macaulay Land Use Research Institute, Craigiebuckler, Aberdeen AB15 8QH
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Abstract

The effect of previous level of body condition on appetite was studied in 47 housed Scottish Blackface ewes, which had been either thin (L: mean condition score 2·15, s.e. 0·030; no. = 24) or fat (H: mean condition score 3·15, s.e. 0·056; no. = 23) 8 weeks before the start of the experiment. The mean daily voluntary food intake (VFI) of a dried grass pellet diet was higher for the L than for the H ewes (2176 v. 1727 g dry matter per day; P < 0·001) during the first 6 weeks of the experiment (period 1). Over this time, live weights increased from 60·5 or 69·9 (s.e.d. 1·68) to 68·4 or 75·6 (s.e.d. 1·94) and condition scores increased from 2·84 or 3·16 (s.e.d. 0·057) to 3·13 or 3·38 (s.e.d. 0·071) for the L and H ewes respectively.

At the end of the 6-week period, plasma insulin concentrations were measured in 10 ewes from each treatment (mean condition scores 3·15 (L) and 3·27 (H) (s.e.d. 0·091)) when fed both ad libitum and at a fixed level of 1200 g/day for consecutive 11-day periods (period 2). Mean VFI was higher for the L than for the H ewes (2191 v. 1661 g dry matter per day; P < 0·05) over the period of ad libitum feeding. There was no effect of feeding level (ad libitum v. 1200 g/day) on mean plasma insulin concentrations, but the mean basal plasma insulin concentration was higher in the H than in the L ewes (43·0 v. 29·0 mil per 1; P < 0·05). Fifteen minutes after the ingestion of a single 400 g meal, the plasma insulin concentration in the H ewes was higher than the mean prefeeding value (63·3 v. 41·7 mil per I; P<0·05) but there was no corresponding increase in the L ewes. The plasma insulin concentration 15 min after the intravenous administration of a single dose of 0·25 U per kg live weight of insulin ivas higher in the H than in the L ewes (1723 v. 1031 mil per 1; P < 0·01) but there were no differences between treatments in plasma glucose concentrations following insulin administration.

It was concluded that previous body condition can affect contemporary VFI and this effect may be mediated by plasma insulin concentrations providing a long-term feedback signal to the brain. Keywords: body condition, food intake, insulin, sheep.

Keywords

body conditionfood intakeinsulinsheep
Type
Research Article
Information
Animal Science , Volume 64 , Issue 2 , April 1997 , pp. 247 - 252
Copyright
Copyright © British Society of Animal Science 1997

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References

Agricultural Research Council. 1980. The nutrient requirements of ruminant livestock. Commonwealth Agricultural Bureaux, Slough.Google Scholar
Bassett, J. M. 1989. Metabolic and endocrine responses of pregnant and lactating ewes to intravenous glucose or insulin. Journal of Agricultural Science, Cambridge 113: 173–182.CrossRefGoogle Scholar
Deetz, L. E. and Wangness, P. J. 1981. Influence of intrajugular administration of insulin, glucagon and propionate on voluntary feed intake of sheep. Journal of Animal Science 53:427–433.CrossRefGoogle ScholarPubMed
Figlewicz, D. P., Sipols, A. J., Seeley, R. J., Chavez, M., Woods, S. C. and Porte, D. 1995. Intraventricular insulin enhances the meal-suppressive efficacy of intraventricular cholecystokinin octapeptide in the baboon. Behavioural Neuroscience 109: 567–569.CrossRefGoogle ScholarPubMed
Foot, J. Z. 1972. A note on the effect of body condition on the voluntary intake of dried grass wafers by Scottish Blackface ewes. Animal Production 14:131–134.Google Scholar
Foster, L. A., Ames, N. K. and Emery, R. S. 1991. Food intake and serum insulin responses to intraventricular infusions of insulin and IGF-1. Physiology of Behaviour 50: 745–749.CrossRefGoogle Scholar
Genstat 5 Committee. 1987. Genstat 5 reference manual. Clarendon Press, Oxford.Google Scholar
Godden, P. M. M. and Weekes, T. E. C. 1981. Insulin, prolactin and thyroxine responses to feeding, and to arginine and insulin injections during growth in lambs. Journal of Agricultural Science, Cambridge 96: 353–362.CrossRefGoogle Scholar
Kaiyala, K. J., Woods, S. C. and Schwartz, M. W. 1995. A new model for the regulation of energy balance and adiposity by the central nervous system. American Journal Clinical Nutrition 62: S1123–S1134.CrossRefGoogle ScholarPubMed
Kenward, M. G. 1987. A method for comparing profiles of repeated measures. Applied Statistics 36: 296–308.CrossRefGoogle Scholar
McCann, J. P., Bergman, E. N. and Beermann, D. H. 1992. Dynamic and static phases of severe dietary obesity in sheep: food intakes, endocrinology and carcass and organ chemical composition. Journal of Nutrition 122: 496–505.CrossRefGoogle ScholarPubMed
McNiven, M. A. 1984. Effect of body fatness on blood metabolites and insulin insensitivity in adult sheep. Canadian Journal of Animal Science 64:1049–1053.CrossRefGoogle Scholar
MacRae, J. C., Bruce, L. A., Hovell, F. D. DeB., Hart, I. C., Inkster, J., Walker, A. and Atkinson, T. 1991. Influence of protein nutrition on the response of growing lambs to exogenous bovine growth hormone. Journal of Endocrinology 130:53–61.CrossRefGoogle ScholarPubMed
Rhind, S. M., Doney, J. M., Gunn, R. G. and Leslie, I. D. 1985. Investigation of the relationships between blood metabolite and metabolic hormone concentrations and gonadotrophin profiles in ewes with different levels of intake at different levels of condition. Hill Farming Research Organisation annual report, 1985, pp. 8–10.Google Scholar
Richardson, T. 1977. A modification of the Tinder Auto Analyzer method for glucose. Annals of Clinical Biochemistry 14: 223–226.CrossRefGoogle Scholar
Russel, A. J. F., Doney, J. M. and Gunn, R. G. 1969. Subjective assessment of body fat in live sheep. Journal Agricultural Science, Cambridge 72: 451–454.CrossRefGoogle Scholar
Schwartz, M. W., Figlewicz, D. P., Baskin, D. G., Woods, S. C. and Porte, D. 1992. Insulin in the brain: a hormonal regulator of energy balance. Endocrine Revieivs 13: 387–414.Google Scholar
Sibbald, A. M. 1997. The effect of body condition on the feeding behaviour of sheep with different times of access to food. Animal Science 64: 239–246.CrossRefGoogle Scholar
Sibbald, A. M. and Kerr, W. G. 1994. The effect of body condition and previous nutrition on the herbage intakes of ewes grazing autumn pastures at two sward heights. Animal Production 58: 231–235.CrossRefGoogle Scholar
Thompson, J. M. and Parks, J. R. 1983. Food intake, growth and mature size in Australian Merino and Dorset Horn sheep. Animal Production 36: 471–479.Google Scholar
Vandermeerschen-Doize, F., Buchat, J. -C., Bouckoms-Vandermeir, M.-A. and Paquay, R. 1983. Effects of long-term ad libitum feeding on plasma lipid components and blood glucose, β-hydroxybutyrate and insulin concentrations in lean adult sheep. Reproduction, Nutrition, Developpement 23: 51–63.CrossRefGoogle ScholarPubMed
Vanderweele, D. A. 1994. Insulin is a prandial satiety hormone. Physiology and Behaviour 56: 619–622.CrossRefGoogle ScholarPubMed
Weekes, T. E. C. 1986. Insulin and growth. In Control and manipulation of animal growth (ed. Buttery, P. J., Haynes, N. B. and Lindsay, D. B.), pp. 187–206. Butterworths, London.CrossRefGoogle Scholar
Weigle, D. S. 1994. Appetite and the regulation of body composition. FASEB Journal 8: 302–310.CrossRefGoogle ScholarPubMed
Woods, S. C. 1988. New perspectives on the role of insulin as an adiposity signal to the brain. Proceedings of the third Benjamin Franklin/Lafayette seminar (ed. Epstein, A., Nikolaidis, S. and Stellar, E.), abstract VI-4 LaNapoule.Google Scholar
Woods, S. C. and Gibbs, J. 1989. The regulation of food intake by peptides. Annals of the New York Academy of Sciences 375: 236–243.CrossRefGoogle Scholar
Woods, S. C., Porte, D., Strubbe, J. H. and Steffens, A. B. 1986. The relationships among body fat, feeding and insulin. In Feeding behaviour. Neural and hormonal controls, pp. 315–327. Academic Press Inc.CrossRefGoogle Scholar