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Effect of active or passive immunization against steroids on reproductive performance of ewes in different levels of body condition at mating

Published online by Cambridge University Press:  02 September 2010

S. M. Rhind ,
B. A. Morris ,
Jill Clayton ,
J. M. Doney ,
R. G. Gunn  and
I. D. Leslie
S. M. Rhind
Affiliation:
Hill Farming Research Organisation, Bush Estate, Penicuik, Midlothian EH26 0PY
B. A. Morris
Affiliation:
Division of Clinical Biochemistry, University of Surrey, Guildford GU2 5XH
Jill Clayton
Affiliation:
Division of Clinical Biochemistry, University of Surrey, Guildford GU2 5XH
J. M. Doney
Affiliation:
Hill Farming Research Organisation, Bush Estate, Penicuik, Midlothian EH26 0PY
R. G. Gunn
Affiliation:
Hill Farming Research Organisation, Bush Estate, Penicuik, Midlothian EH26 0PY
I. D. Leslie
Affiliation:
Hill Farming Research Organisation, Bush Estate, Penicuik, Midlothian EH26 0PY
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Abstract

Border Leicester × Scottish Blackface (Greyface) ewes of three groups, each comprising 118 animals in a wide range of body condition scores, were mated at a synchronized oestrus in mid October. The ewes were passively immunized against testosterone (group P), actively immunized against androstenedione (group F), or not treated (group C). All ewes were slaughtered at return to service or at 35 to 45 days of pregnancy and ovulation rates and numbers of embryos present were determined. Mean ovulation rates of ewes in group P were higher than in those in group C (P < 0·05) and this difference was evident at most levels of body condition. The absolute increase in ovulation rate, compared with the control group, was similar at all condition scores. Mean ovulation rates of ewes in group F were higher than those in group C (P < 0·001) and the magnitude of the increase was greater in ewes in higher condition scores. The incidence of ova wastage was variable but differences between treatments in mean ovulation rate were generally reflected in mean litter size. The conception rates of immunized ewes were depressed compared with those of control animals, particularly in ewes with a body condition score less than 3·0 at mating. Consequently, there was no improvement in the potential lambing rate of immunized ewes following only one cycle of mating. Circulating antibody titres were not related to conception rate or body condition at mating and were related to ovulation rate only in group F ewes. It is concluded that immunization against steroids, using either passive or active techniques, can improve the reproductive performance of individual ewes but improvement in the performance of the flock as a whole may only be achieved under optimal conditions of nutrition and season.

Type
Research Article
Information
Animal Production , Volume 43 , Issue 2 , October 1986 , pp. 285 - 292
Copyright
Copyright © British Society of Animal Science 1986

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References

REFERENCES

Cox, R. I., Wilson, P. A., Scaramuzzi, R. J., Hoskinson, R. M., George, J. M. and Bindon, B. M. 1982. The active immunization of sheep against oestrone, androstenedione or testosterone to increase twinning. Proceedings of the Australian Society of Animal Production 14: 511–514.Google Scholar
Doney, J. M., Gunn, R. G. and Griffiths, J. G. 1973. The effect of premating stress on the onset of oestrus and on ovulation rate in Scottish Blackface ewes. Journal of Reproduction and Fertility 35: 381–384.CrossRefGoogle ScholarPubMed
Edey, T. N. 1969. Prenatal mortality in the sheep: a review. Animal Breeding Abstracts 37: 173–190.Google Scholar
Edey, T. N. 1976. Embryo mortality. In Sheep Breeding, Proceedings of International Congress, Muresk and Perth, Western Australia (ed. Tomes, G. J.), pp. 400–410. Western Australia Institute of Technology.Google Scholar
Geldard, H. and Scaramuzzi, R. J. 1983. Immunizing ewes to increase lambing percentage — further developments. Proceedings of Western Australian Wheat Sheep Review, Farm Management Foundation of Australia, pp. 39–51.Google Scholar
Geldard, H., Scaramuzzi, R. J. and Wilkins, J. F. 1984. Immunization against polyandroalbumin leads to increases in lambing and tailing percentages. New Zealand Veterinary Journal 32: 2–5.CrossRefGoogle ScholarPubMed
Gunn, R. G. and Doney, J. M. 1975. The interaction of nutrition and body condition at mating on ovulation rate and early embryo mortality in Scottish Blackface ewes. Journal of Agricultural Science, Cambridge 85: 465–470.CrossRefGoogle Scholar
Gunn, R. G., Doney, J. M. and Russel, A. J. F. 1972. Embryo mortality in Scottish Blackface ewes as influenced by body condition at mating and by postmating nutrition. Journal of Agricultural Science, Cambridge 79: 19–25.CrossRefGoogle Scholar
Gunn, R. G., Doney, J. M. and Smith, W. F. 1979. The effect of time of mating on ovulation rate and potential lambing rate of Greyface ewes. Animal Production 29: 277–282.Google Scholar
Land, R. B., Morris, B. A., Baxter, G., Fordyce, M. and Forster, J. 1982. Improvement of sheep fecundity by treatment with antisera to gonadal steroids. Journal of Reproduction and Fertility 66: 625–634.CrossRefGoogle ScholarPubMed
Martin, G. B., Scaramuzzi, R. J., Cox, R. I. and Gherardi, P. B. 1979. Effects of active immunisation against androstenedione or oestrone on oestrus, ovulation and lambing in Merino ewes. Australian Journal of Experimental Agriculture and Animal Husbandry 19: 673–678.CrossRefGoogle Scholar
Meat and Livestock Commission. 1983. Feeding the Ewe. Sheep Improvement Services, Milton Keynes.Google Scholar
Nancarrow, C. D., Murray, J. D.Scaramuzzi, R. J., Marshall, J. T., Hazelton, I. G., Hoskinson, R. M. and Boland, M. P. 1985. Fertilization and embryo development in androstenedione-immune sheep. Proceedings of the Australian Society of Reproductive Biology, Adelaide, p. 6.Google Scholar
Rhind, S. M., Gunn, R. G., Doney, J. M. and Leslie, I. D. 1984. A note on the reproductive performance of Greyface ewes in moderately fat and very fat condition at mating. Animal Production 38: 305–307.Google Scholar
Rhind, S. M., Gunn, R. G., Morris, B. A., Clayton, J., Leslie, I. D. and Gittus, G. 1985. Effect of passive immunization against testosterone on the reproductive performance of Scottish Blackface ewes in different levels of body condition at mating. Animal Production 41: 97–102.Google Scholar
Rhind, S. M., Robinson, J. J., Fraser, C. and McHattie, I. 1980. Ovulation and embryo survival rates and plasma progesterone concentrations of prolific ewes treated with PMSG. Journal of Reproduction and Fertility 58: 139–144.CrossRefGoogle ScholarPubMed
Robinson, T. J. 1971. The seasonal nature of reproductive phenomena in the sheep. 2. Variation in fertility following synchronisation of oestrus. Journal of Reproduction and Fertility 24: 19–27.CrossRefGoogle Scholar
Scaramuzzi, R. J., Geldard, H., Beels, C. M., Hoskinson, R. M. and Cox, R. I. 1983. Increased lambing percentages through immunization against steroid hormones. Wool Technology and Sheep Breeding 31: 87–97.Google Scholar
Scaramuzzi, R. J. and Hoskinson, R. M. 1984. Active immunization against steroid hormones for increasing fecundity. In Immunological Aspects of Reproduction in Mammals (ed. Crighton, D. B.), pp. 445–474. Butterworths, London.CrossRefGoogle Scholar
Smith, J. F. 1983. Towards multiple ovulations — steroid immunisation techniques and results. Proceedings of 13th Seminar of the Sheep and Beef Cattle Society of New Zealand Veterinary Association, Waikato University, pp. 35–43.Google Scholar
Van Look, P. F. A., Clarke, I. J., Davidson, W. G. and Scaramuzzi, R. J. 1978. Ovulation and lambing rates in ewes actively immunized against androstenedione. Journal of Reproduction and Fertility 53: 129–130.CrossRefGoogle ScholarPubMed