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Absorption and metabolism of [U-14C] acetic acid in growing pigs

Published online by Cambridge University Press:  02 September 2010

Eva A. Latymer ,
H. D. Keal  and
A. G. Low
Eva A. Latymer
Affiliation:
AFRC Institute for Grassland and Environmental Research Shinfield, Reading
H. D. Keal
Affiliation:
AFRC Institute for Grassland and Environmental Research Shinfield, Reading
A. G. Low
Affiliation:
AFRC Institute for Grassland and Environmental Research Shinfield, Reading
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Abstract

By tracing 14C after an injection of [U-14C] sodium acetate into the caecum of pigs, it was found that proportionately 0·93 of the acetate injected was absorbed. About 0·25 of the administered acetate was recovered in the body 96 h later. It is assumed that the remainder was oxidized during this period and exhaled as carbon dioxide.

The 14C initially predominated in plasma lipids, but it progressively shifted over the 96 h to plasma proteins. In the lipid fraction of blood plasma there was a continuous shift of 14C from triglycerides and free cholesterol to cholesterol esters over the 96-h period of measurement.

In the body most of the 14C was recovered in the fat, liver and intestinal wall. The highest concentration of 14C was in the bile, especially in glycine-conjugated bile acids.

It was shown that the absorbed acetate was a source of energy to the pigs and it was recycled and metabolized into more complex components in the body during 96 h.

Keywords

acetic acidenergy intakemetabolismpigs
Type
Research Article
Information
Animal Production , Volume 52 , Issue 2 , April 1991 , pp. 331 - 336
Copyright
Copyright © British Society of Animal Science 1991

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