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Reproduction of wild Mongolian gerbils bred in the laboratory with respect to generation and season 2. Spermatogenic activity and testicular testosterone concentration

Published online by Cambridge University Press:  09 March 2007

S. Blottner  and
I.W. Stuermer
S. Blottner*
Affiliation:
Institute for Zoo and Wildlife Research, PF 601103, D-10252, Berlin, Germany
I.W. Stuermer
Affiliation:
Georg-August-University Göttingen, Sensory Developmental Research Group, Robert-Koch-Strasse 40, D-37075, Göttingen, Germany
*
†E-mail: [email protected]
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Abstract

Testicular activity of wild and laboratory strains of Meriones unguiculatus and its seasonal dependence was studied. Comparative intraspecific measurements were performed in adult males of the laboratory strain (LAB) and in male offspring of wild Mongolian gerbils (WF-1 to WF-3). All animals were reared under identical conditions including a constant light regime. LAB and WILD were examined in January, July and October. Testicular spermatozoa were counted, proportions of different cell types were analysed using DNA flow cytometry, and total germ cell transformation was calculated from DNA histograms. Intratesticular testosterone concentrations were measured with an enzyme immunoassay. The results showed that differences of testicular activity are dependent on the season as well as the strain and the generation. The season affected testicular parameters in LAB resulting in lowered testosterone and sperm production in July and October, respectively. In contrast, all testicular cell parameters were significantly lower for WF-1 in January compared with October. These seasonal differences were neutralized or diminished in WF-2 and WF-3. In the WILD, total testicular activity was lower and varied more in all months studied, but the differences compared with the values in LAB decreased in the successive generations. WF-3 showed the lowest discrepancy of testis weight and spermatogenic output compared with LAB. The data suggest endogenous cues for seasonal regulation of spermatogenesis, but this endogenous rhythm seems to be subsided or lost rapidly. These findings indicate rapid, adaptive changes in the early offspring generations from wild populations during breeding in the laboratory.

Keywords

domesticationgerbilsseasonalityspermatogenesistestosterone
Type
Research Article
Information
Animal Science , Volume 82 , Issue 3 , June 2006 , pp. 389 - 395
Copyright
Copyright © British Society of Animal Science 2006

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References

Arrington, L. R., Beaty, T. C. and Kelly, K. C. 1973. Growth, longevity, and reproduction life of the Mongolian gerbil. Laboratory Animal Science 23: 262–265.Google ScholarPubMed
Blottner, S., Franz, C., Rohleder, M., Zinke, O. and Stuermer, I. W. 2000. Higher testicular activity in laboratory gerbils compared to wild Mongolian gerbils (Meriones unguiculatus). Journal of Zoology 250: 461–466.CrossRefGoogle Scholar
Blottner, S., Hingst, O. and Meyer, H. H. D. 1996. Seasonal spermatogenesis and testosterone production in roe deer (Capreolus capreolus). Journal of Reproduction and Fertility 108: 299–305.CrossRefGoogle ScholarPubMed
Cheal, M. 1983. Lifespan ontogeny of breeding and reproductive success in Mongolian gerbils. Laboratory Animals 17: 240–245.CrossRefGoogle ScholarPubMed
Cheal, M. and Foley, K. 1985. Developmental and experimental influences on ontogeny: the gerbil (Meriones unguiculatus) as a model. Journal of Comparative Physiology and Psychology 99: 289–305.CrossRefGoogle Scholar
Clark, M. M. and Galef, B. G. 1980. Effects of rearing environment on adrenal weights, sexual development, and behavior in gerbils: an examination of Richter's domestication hypothesis. Journal of Comparative Physiology and Psychology 94: 857–863.CrossRefGoogle ScholarPubMed
Evenson, D. P., Baer, R. K., Jost, L. K. and Gesch, R. W. 1986. Toxicity of thiotepa on mouse spermatogenesis as determined by dual-parameter flow cytometry. Toxicology and Applied Pharmacology 82: 151–163.CrossRefGoogle ScholarPubMed
Haase, E. 1980. Physiologische Aspekte der Domestikation. Zoologischer Anzeiger 204: 265–281.Google Scholar
Hacker-Klom, U. B. 1995. Age dependency of murine spermatogenesis. Zeitschrift für Naturforschung C 50: 303–310.CrossRefGoogle ScholarPubMed
Herre, W. and Röhrs, M. 1990. Haustiere - zoologisch gesehen. 2. Aufl. Gustav Fischer-Verlag, Stuttgart.CrossRefGoogle Scholar
Janca, F. C., Jost, L. K. and Evenson, D. P. 1986. Mouse testicular and sperm cell development characterized from birth to adulthood by dual parameter flow cytometry. Biology of Reproduction 34: 613–623.CrossRefGoogle ScholarPubMed
Kramer, A. W. 1964. Body and organ weights and linear measurements of the adult Mongolian gerbil. Anatomical Record 150: 343–348.CrossRefGoogle ScholarPubMed
Kunzl, C. and Sachser, N. 1999. The behavioral endocrinology of domestication: a comparison between the domestic guinea pig (Cavia apera f. porcellus) and its wild ancestor, the cavy (Cavia aperea). Hormones and Behavior 35: 28–37.CrossRefGoogle Scholar
Marston, J. H. and Chang, M. C. 1965. The breeding, management and reproductive physiology of the Mongolian gerbil (Meriones unguiculatus). Laboratory Animal Care 15: 34–48.Google ScholarPubMed
Mason, I. L. 1984. Evolution of domesticated animals. Longman, London.Google Scholar
Meyer, H. H. D. and Hoffmann, B. 1987. Development of a sensitive microtiterplate enzyme immunoassay for the anabolic steroid trenbolone. Food Additives and Contaminants 4: 149–160.CrossRefGoogle Scholar
Naumov, N. P. and Lobachev, V. S. 1975) Ecology of desert rodents of the USSR. In Rodents in desert environments (ed. Prakash, T. and Gosh, M.), pp. 295–299. Junk, The Hague.Google Scholar
Price, E. O. 2002. Animal domestication and behaviour. CABI Publishing, Wallingford.CrossRefGoogle Scholar
Probst, B. 1987. Developmental changes in the pituitary-gonadal-axis in male Mongolian gerbils from birth to adulthood. Experimental and Clinical Endocrinology 90: 157–166.CrossRefGoogle ScholarPubMed
Rich, S. T. 1968. The Mongolian gerbil (Meriones unguiculatus) in research. Laboratory Animal Care 18: 235–243.Google ScholarPubMed
Segatelli, T. M., Almeida, C. C., Pinheiro, P. F., Martinez, M., Padovani, C. R. and Martinez, F. E. 2002. Kinetics of spermatogenesis in the Mongolian gerbil (Meriones unguiculatus). Tissue and Cell 34: 7–13.CrossRefGoogle ScholarPubMed
Spano, M., Bartoleschi, C., Cordelli, E., Segre, L., Mantovani, A., Fazzi, P. and Pacchierotti, F. 1996. Flow cytometric and histological assessment of diepoxybutane toxicity on mouse spermatogenesis. Journal of Toxicology and Environmental Health 47: 423–441.CrossRefGoogle ScholarPubMed
Statistical Packages for the Social Sciences. 2000. SPSS version 9.0. SPSS Chicago, IL.Google Scholar
Stuermer, I. W., Plotz, K., Leybold, A., Zinke, O., Kalberlah, O., Samjaa, R. and Scheich, H. 2003. Intraspecific allometric comparison of laboratory gerbils with Mongolian gerbils trapped in the wild indicates domestication in Meriones unguiculatus (Milne-Edwards, 1867) (Rodentia: Gerbillinae). Zoologischer Anzeiger 242: 249–266.CrossRefGoogle Scholar
Stuermer, I.W., Plotz, K., Wetzel, W., Wagner, T., Leybold, A. and Scheich, H. 1997. Reduced brain size and faster auditory discrimination learning in laboratory gerbils compared to wild Mongolian gerbils (Meriones unguiculatus). Social Neuroscience 23: 2067 (abstr.)Google Scholar
Stuermer, I. W., Tittmann, C., Schilling, C. and Blottner, S. 2006. Reproduction of wild gerbils bred in the laboratory in dependence on generation and season. 1. Morphological changes and fertility lifespan. Animal Science 82: 377–387.CrossRefGoogle Scholar