Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-26T13:54:52.653Z Has data issue: false hasContentIssue false
  • English
  • Français

Effects of nutrition on hormone profiles and patterns of deiodinase activity in the skin and associated patterns of hair follicle activity and moult in cashmere goats

Published online by Cambridge University Press:  09 March 2007

S. M. Rhind ,
C. E. Kyle ,
D. J. Riach  and
E. I. Duff
S. M. Rhind*
Affiliation:
Macaulay Institute, Craigiebuckler, Aberdeen, AB15 8QH, UK
C. E. Kyle
Affiliation:
Macaulay Institute, Craigiebuckler, Aberdeen, AB15 8QH, UK
D. J. Riach
Affiliation:
Macaulay Institute, Craigiebuckler, Aberdeen, AB15 8QH, UK
E. I. Duff
Affiliation:
Biomathematics and Statistics Scotland, Macaulay Institute, Craigiebuckler, Aberdeen, AB15 8QH, UK
*
†Email: [email protected]
Get access

Abstract

The effects of nutrition on patterns of live-weight change, hair follicle activity, moult, hormone profiles and associated activities of monodeiodinase enzyme types II and III (MDII and MDIII) in cashmere goats were investigated. From 1 week before the winter solstice (mid December), one group of 15 animals was given a ration designed to provide 2·0 × live weight maintenance requirements (high; H) while a second, similar, group was given 0·8 × live weight maintenance requirements (low; L). After approximately 3 months, L animals had significantly lower mean live weights (P<0·01) than H animals. This was associated with lower (P<0·05) overall mean hair follicle activity in L than H animals during the March to May period and a lower overall mean moult score during March and April in L animals (P<0·01) but a similar mean date of moult onset. Mean concentrations of all of the hormones measured exhibited significant changes (P<0·01) with date of sampling. Overall mean concentrations of insulin, tri-iodothyronine and thyroxine did not differ with treatment but, compared with L animals, H animals exhibited higher mean concentrations of prolactin in April and May (P<0·05) and of insulin-like growth factor-1 in December and January (P<0·001). Rates of activity of MDII and MDIII in skin differed with date (P<0·001) but were not significantly affected by nutritional treatment. The MDIII/MDII ratio differed (P=0·05) with month but was significantly higher (P<0·05) in L than H animals in January, only. It is concluded that the reduction in hair follicle activity and the slower onset of moult associated with reduced nutrition were unlikely to be controlled, directly, by differences in activities of MDII or MDIII in skin tissue.

Keywords

cashmeredeiodinasegoatshair follicleshormonesnutrition
Type
Research Article
Information
Animal Science , Volume 82 , Issue 5 , October 2006 , pp. 723 - 730
Copyright
Copyright © British Society of Animal Science 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Agricultural Research Council. 1980. Nutritional requirements of ruminant livestock. Commonwealth Agricultural Bureaux, Slough, UK.Google Scholar
Beckett, G. J. and Arthur, J. A. 1994. The iodothyroinine deiodinases and 5′-deiodination. In Clinical endocrinology and metabolism (Sheppard, M. D. and Stewart, P. M.), pp. 285–305. Ballière Tindall, London.Google Scholar
Bruce, L. A., Atkinson, T., Hutchinson, J. S. M.Shakespear, R. A. and MacRae, J. C. 1991. The measurement of insulin-like growth factor I in sheep plasma. Journal of Endocrinology 128: R1–R4.CrossRefGoogle ScholarPubMed
Choy, V. J., Nixon, A. J. and Pearson, A. J. 1997. Distribution of prolactin receptor immunoreactivity in ovine skin and changes during the wool follicle growth cycle. Journal of Endocrinology 155: 265–275.CrossRefGoogle ScholarPubMed
Dicks, P., Russel, A. J. F. and Lincoln, G. A. 1994. The role of prolactin in the reactivation of hair follicles and the spring moult in goats. Journal of Endocrinology 143: 441–448.CrossRefGoogle ScholarPubMed
Forbes, J. M., Driver, P. M., El-Shahat, A. A. and Boaz, T. G. 1975. The effect of daylength and level of feeding on serum prolactin in growing lambs. Journal of Endocrinology 64: 549–554.CrossRefGoogle ScholarPubMed
Harris, P. M., McBride, B. W., Gurnsey, M. P., Sinclair, B. R. and Lee, J. 1993. Direct infusion of a variant of insulin-like growth factor-1 into the skin of sheep and effects on local blood flow, amino acid utilization and cell replication. Journal of Endocrinology 139: 463–472.CrossRefGoogle ScholarPubMed
McGregor, B. A. 1998. Nutrition, management and other environmental influences on the quality and production of mohair and cashmere with particular reference to Mediterranean and annual temperate climatic zones: a review. Small Ruminant Research 28: 199–215.CrossRefGoogle Scholar
McNeilly, A. S. and Andrews, P. 1974. Purification and characterisation of caprine prolactin. Journal of Endocrinology 60: 359–367.CrossRefGoogle ScholarPubMed
MacRae, J. C., Bruce, L. A., Hovell, F. D. deB.Hart, I. C., Inkster, J. and Atkinson, T. 1991. Influence of protein nutrition on the response of growing lambs to exogenous bovine growth hormone. Journal of Endocrinology 130: 53–61.CrossRefGoogle ScholarPubMed
Merchant, M. and Riach, D. J. 1996. Changes in the coat of cashmere goat kids of two different genotypes from birth to 13 months of age. Animal Science 62: 317–323.CrossRefGoogle Scholar
Merchant, M. and Riach, D. J. 2002. The effect of plane of nutrition and shearing on the pattern of the moult in Scottish Cashmere goats. Animal Science 74: 177–188.CrossRefGoogle Scholar
Murphy, L. J., Tachibana, K. and Friesen, H. G. 1988. Stimulation of hepatic insulin-like growth factor-1 gene expression by ovine prolactin: evidence for intrinsic somatogenic activity in the rat. Endocrinology 122: 2027–2033.CrossRefGoogle ScholarPubMed
Nicol, F., Lefranc, H., Arthur, J. R. and Trayhurn, P. 1994. Characterization and postnatal development of 5′-deiodinase activity in goat perirenal fat. American Journal of Physiology 267: R144–R149.Google ScholarPubMed
Nixon, A. J. 1993. A method for determining the activity state of hair follicles. Biotechnic and Histochemistry 68: 316–325.CrossRefGoogle ScholarPubMed
Nixon, A. J., Ford, C. A., Oldham, J. M. and Pearson, A. J. 1997. Localisation of insulin-like growth factor receptors in skin follicles of sheep ( Ovis aries ) and changes during an induced growth cycle. Comparative Biochemistry and Physiology 118A 1247–1257.CrossRefGoogle Scholar
Rhind, S. M., Kyle, C. E. and Duff, E. I. 2004. Effects of season and of manipulation of circulating prolactin concentrations on deiodinase activity in cashmere goat skin. Australian Journal of Agricultural Research 55: 211–221.CrossRefGoogle Scholar
Rhind, S. M. and Kyle, C. E. 2004. Skin deiodinase profiles and associated patterns of hair follicle activity in cashmere goats of contrasting genotypes. Australian Journal of Agricultural Research 55: 443–448.CrossRefGoogle Scholar
Rhind, S. M. and McMillen, S. R. 1995a. Seasonal patterns of secondary fibre growth, moulting and hair follicle activity in Siberian and Icelandic × Scottish feral goats offered high and low levels of protein. Small Ruminant Research 16: 69–76.CrossRefGoogle Scholar
Rhind, S. M. and McMillen, S. R. 1995b. Seasonal changes in systemic hormone profiles and their relationship to patterns of fibre growth and moulting in goats of contrasting genotypes. Australian Journal of Agricultural Research 46: 1273–1283.CrossRefGoogle Scholar
Rhind, S. M. and McMillen, S. R. 1996. Effects of methylthiouracil treatment on the growth and moult of cashmere fibre in goats. Animal Science 62: 513–520.CrossRefGoogle Scholar
Richards, M. W., Spicer, L. J. and Wetteman, R. P. 1995. Influence of diet and ambient temperature on bovine serum insulin-like growth factor-1 and thyroxine: relationships with non-esterified fatty acids, glucose, insulin, luteinizing hormone and progesterone. Animal Reproduction Science 37: 267–279.CrossRefGoogle Scholar
Russel, A. J. F. 1992. Fibre production from sheep and goats. In Progress in sheep and goat research (ed. Speedy, A. W.), pp. 235–256, CAB International, Oxon.Google Scholar
Ryder, M. 1960. A study of the coat of the mouflon ( Ovis musimon ) with special reference to seasonal change. Proceedings of the Zoological Society of London 135: 387–405.CrossRefGoogle Scholar
Ryder, M. L. and Stephenson, S. K. 1968. Wool growth. Academic Press, London.Google Scholar
Villar, D., McMillen, S. R., Dicks, P. and Rhind, S. M. 2000a. The roles of thyroid hormones and prolactin in the control of fibre moult and associated changes in hair follicle activities in cashmere goats. Australian Journal of Agricultural Research 51: 407–414.CrossRefGoogle Scholar
Villar, D., Nicol, F., Arthur, J. R., Dicks, P., Cannavan, A., Kennedy, D. G. and Rhind, S. M. 2000b. Type II and type III monodeiodinase activites in the skin of untreated and propylthiouracil-treated cashmere goats. Research in Veterinary Science 68: 119–123.CrossRefGoogle Scholar