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The effect of immunoneutralization of PMSG at a gonadotropin-induced oestrus on the duration of ovulation and reproductive performance of sows

Published online by Cambridge University Press:  02 September 2010

R. N. Kirkwood ,
N. M. Soede ,
G. W. Dyck  and
P. A. Thacker
R. N. Kirkwood
Affiliation:
Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0W0
N. M. Soede
Affiliation:
Department of Animal Husbandry, Agricultural University, Wageningen, The Netherlands
G. W. Dyck
Affiliation:
Agriculture and Agri-food Canada Research Centre, Brandon, Manitoba, Canada R7A 5Y3
P. A. Thacker
Affiliation:
Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0W0
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Abstract

Two experiments were performed to examine the effects of immunoneutralizing PMSG at the onset of oestrus on the reproductive performance of sows. In experiment 1, 12 multiparous sows received 750 i.u. PMSG at weaning and six sozus acted as controls and were injected with saline. At 84 h after PMSG injection, all sows received an injection of 500 i.u. human chorionic gonadotropin (hCG) and six of the PMSG-treated sows also received an injection of 750 i.u. of a monoclonal anti-PMSG serum. The ovaries of all sows were examined by real time ultrasonography at 60-min intervals from 36 to 48 h after hCG injection for evidence of ovulation. In sows observed to ovulate, there was no significant effect of treatment on the interval from hCG injection to the start of ovulation, the duration of ovulation or subsequent litter size. In experiment 2, 253 primiparous sows received injections at weaning of 750 i.u. PMSG (no. = 134), 400 i.u. PMSG plus 200 i.u. hCG (no. = 69) or served as controls (no. = 50). At breeding, 67 of the PMSG-treated sows received an injection of 750 i.u. of monoclonal anti-PMSG serum.

More gonadotropin-treated than control sows were bred by 7 days after weaning (P < 0·05). Farrowing rates were higher in sows receiving the PMSG followed by anti-PMSG and PMSG plus hCG than in controls (P < 0·05), with those receiving PMSG alone being intermediate. There was no effect of treatment on subsequent litter sizes. These data indicate that the reproductive performance of primiparous sows may be improved by gonadotropin administration at the time of weaning. However, there was no advantage to using any particular hormone combination or anti-PMSG.

Keywords

immunoneutralizationovulationPMSGreproductive performancesows
Type
Research Article
Information
Animal Science , Volume 61 , Issue 2 , October 1995 , pp. 321 - 324
Copyright
Copyright © British Society of Animal Science 1995

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