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Differences in food resource allocation in a long-term selection experiment for litter size in mice 2. Developmental trends in body weight against food intake

Published online by Cambridge University Press:  18 August 2016

W. M. Rauw ,
P. Luiting ,
M. W. A. Verstegen ,
O. Vangen  and
P. W. Knap
W. M. Rauw
Affiliation:
Department of Animal Science, Agricultural University of Norway, PO Box 5025, 1432 Ås, Norway
P. Luiting
Affiliation:
PIC International Group Ltd, Roslin Institute, Roslin, Midlothian EH25 9PS, UK
M. W. A. Verstegen
Affiliation:
Animal Nutrition Group, Wageningen Institute of Animal Science, PO Box 338, 6700 AH Wageningen, The Netherlands
O. Vangen
Affiliation:
Department of Animal Science, Agricultural University of Norway, PO Box 5025, 1432 Ås, Norway
P. W. Knap
Affiliation:
PIC International Group Ltd, Roslin Institute, Roslin, Midlothian EH25 9PS, UK
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Abstract

In the accompanying paper, specific genetic factors for body weight and food intake were identified in non-reproductive male and female mice of a line selected for high litter size at birth (average of 22 born per litter) and a non-selected control line (average of 10 born per litter). The existence of these factors are indicated by variation in efficiency parameters such as growth efficiency and maintenance requirements. Residual food intake (RFI) and Parks’ estimates of growth efficiency (AB) and maintenance requirements (MEm) were used to quantify these factors. In the growing period, females had a higher RFI (are less efficient) than males. At maturity, selected mice had higher RFI than control mice and selected females had higher RFI than selected males. AB was higher in selected-line mice than in control-line mice, and higher in males than in females. MEm was higher in selected-line mice than in control-line mice, and higher in females than in males. The results indicate the existence of specific genetic factors for both growth efficiency and maintenance requirements. Selected females may increase RFI in the adult state to anticipate the metabolically stressful periods of pregnancy and lactation, to support a genetically highly increased litter size.

Keywords

food intakegrowthlitter sizeselection
Type
Breeding and genetics
Information
Animal Science , Volume 71 , Issue 1 , August 2000 , pp. 39 - 47
Copyright
Copyright © British Society of Animal Science 2000

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