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Pestivirus control programs: how far have we come and where are we going?

Published online by Cambridge University Press:  08 June 2015

Volker Moennig  and
Paul Becher
Volker Moennig*
Affiliation:
Department of Infectious Diseases, Institute for Virology, University of Veterinary Medicine, Bünteweg 17, D-30559 Hannover, Germany
Paul Becher
Affiliation:
Department of Infectious Diseases, Institute for Virology, University of Veterinary Medicine, Bünteweg 17, D-30559 Hannover, Germany
*
*Corresponding author. E-mail: [email protected]
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Abstract

Classical swine fever (CSF) is endemic in large parts of the world and it is a major threat to the pig industry in general. Vaccination and stamping out have been the most successful tools for the control and elimination of the disease. The systematic use of modified live vaccines (MLV), which are very efficacious and safe, has often preceded the elimination of CSF from regions or countries. Oral vaccination using MLV is a powerful tool for the elimination of CSF from wild boar populations. Bovine virus diarrhea (BVD) is endemic in bovine populations worldwide and programs for its control are only slowly gaining ground. With two genotypes BVD virus (BVDV) is genetically more diverse than CSF virus (CSFV). BVDV crosses the placenta of pregnant cattle resulting in the birth of persistently infected (PI) calves. PI animals shed enormous amounts of virus for the rest of their lives and they are the reservoir for the spread of BVDV in cattle populations. They are the main reason for the failure of conventional control strategies based on vaccination only. In Europe two different approaches for the successful control of BVD are being used: Elimination of PI animals without or with the optional use of vaccines, respectively.

Keywords

bovine viral diarrheaclassical swine feverpestivirus control
Type
Review Article
Information
Animal Health Research Reviews , Volume 16 , Issue 1 , June 2015 , pp. 83 - 87
Copyright
Copyright © Cambridge University Press 2015 

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