Hostname: page-component-78c5997874-94fs2 Total loading time: 0 Render date: 2024-11-05T16:47:32.157Z Has data issue: false hasContentIssue false

Genetics, environment and bovine respiratory disease

Published online by Cambridge University Press:  15 December 2009

Gary Snowder*
Affiliation:
National Center for Foreign Animal and Zoonotic Disease Defense, 200 Discovery Drive, College Station, TX 77843-2129, USA

Abstract

The heritability estimates for resistance and/or susceptibility to bovine respiratory disease (BRD) are small, suggesting response to direct selection will be slow. The number of mammalian genetic markers associated with resistance to specific pathogens or improved immunity is increasing and will provide additional information for developing selection criteria for producing animals with an innate resistance to BRD. Environmental and management factors play significant roles in the prevalence of BRD and must be considered in a holistic approach to reducing BRD. Although no single solution for preventing BRD is likely to be discovered in the immediate future, the long-term outlook appears very promising.

Type
Review Article
Copyright
Copyright © Cambridge University Press 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Aich, P, Babiuk, LA, Potter, AA and Griebel, P (2009). Biomarkers for prediction of bovine respiratory disease outcome. OMICS Journal of Integrative Biology 13: 111.CrossRefGoogle ScholarPubMed
Assie, S, Seegers, H and Beaudeau, F (2004). Incidence of respiratory disorders during housing in non-weaned Charolais calves in cow-calf farms of Pays de la Loire (western France). Preventative Veterinary Medicine 63: 271282.CrossRefGoogle Scholar
Bryson, DG (1985). Calf pneumonia. Veterinary Clinics of North American Food Animal Practice 2: 237242.CrossRefGoogle Scholar
Callan, RJ and Garry, FB (2002). Biosecurity and bovine respiratory disease. Veterinary Clinics of North American Food Animal Practice 18: 5777.CrossRefGoogle ScholarPubMed
Casas, E and Snowder, GD (2008). A putative quantitative trait locus on chromosome 20 associated with bovine pathogenic disease incidence. Journal of Animal Science 86: 24552460.CrossRefGoogle ScholarPubMed
Cusack, PMV, McMeniman, NP and Lean, IJ (2007). Feedlot entry characteristics and climate: their relationship with cattle growth rate, bovine respiratory disease and mortality. Australian Veterinary Journal 85: 311316.Google Scholar
Donaldson, L, Vuocolo, T, Gray, C, Strandberg, Y, Reverter, A, McWilliam, S, Wang, Y, Byrne, K and Tellam, R (2005). Construction and validation of a bovine innate immune microarray. BMC Genomics 6: 135 (22 pgs). www.biomedcentral.com/1471-2164/6/135Google Scholar
Duff, GS and Galyean, ML (2007). Recent advances in management of highly stress, newly received feedlot cattle. Journal of Animal Science 85: 823840.Google Scholar
Ellis, JA (2001). The immunology of the bovine respiratory disease complex. Veterinary Clinics of North America Food Animal Practice 17: 535549.CrossRefGoogle ScholarPubMed
Fett, T, Zecchinon, L, Vanden Bergh, P and Desmecht, D (2008). Mannheimia haemolytica leukotoxin-induced cytolysis of caprine (Capra hircus) leukocytes is mediated by the CD18 subunit of β2-integrins. Microbial Pathogenesis 45: 337342.CrossRefGoogle ScholarPubMed
May, BJ, Zhang, Q, Li, LL, Paustian, ML, Whittam, TS and Kapur, V (2001). Complete genomic sequence of Pasteurella multocida, Pm70. Proceedings National Academy of Sciences, USA 98: 34603465.Google Scholar
Muggli-Cockett, NE, Cundiff, LV and Gregory, KE (1992). Genetic analysis of bovine respiratory disease in beef calves during the first year of life. Journal of Animal Science 70: 20132019.Google Scholar
Salak-Johnson, JL and McGlone, JJ (2007). Making sense of apparently conflicting data: stress and immunity in swine and cattle. Journal of Animal Science 85 (Electronic Supplement): E81E88.CrossRefGoogle ScholarPubMed
Snowder, GD, Van Vleck, LD, Cundiff, LV and Bennett, GL (2005). Influence of breed, heterozygosity, and disease incidence on estimates of variance components of respiratory disease in preweaned beef calves. Journal of Animal Science 83: 12471261.CrossRefGoogle ScholarPubMed
Snowder, GD, Van Vleck, LD, Cundiff, LV and Bennett, GL (2006). Bovine respiratory disease in feedlot cattle: environmental, genetic, and economic factors. Journal of Animal Science 84: 19992008.CrossRefGoogle ScholarPubMed
Snowder, GD, Van Vleck, LD, Cundiff, LV, Bennett, GL, Koohmaraie, M and Dikeman, ME (2007). Bovine respiratory disease in feedlot cattle: Phenotypic, environmental, and genetic correlations with growth, carcass, and longissimus muscle palatability traits. Journal of Animal Science 85: 18851892.CrossRefGoogle ScholarPubMed
Zecchinon, L, Fett, T and Desmecht, D (2005). How Mannheimia haemolytica defeats host defence through a kiss of death mechanism. Veterinary Research 36: 133156.CrossRefGoogle ScholarPubMed