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Duration of immunity induced by companion animal vaccines

Published online by Cambridge University Press:  29 October 2010

James A. Roth  and
Anna Rovid Spickler
James A. Roth*
Affiliation:
Center for Food Security and Public Health, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
Anna Rovid Spickler
Affiliation:
Center for Food Security and Public Health, College of Veterinary Medicine, Iowa State University, Ames, IA, USA
*
*Corresponding author. E-mail: [email protected]
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Abstract

Concerns about possible adverse effects from annual vaccination have prompted the reanalysis of vaccine protocols for cats and dogs. In the last decade, several veterinary advisory groups have published protocols that recommend extended revaccination intervals for certain ‘core’ vaccines. In addition, practicing veterinarians have been asked to consider vaccination as an individualized medical procedure, based on an analysis of risks and benefits for each vaccine in an individual animal. The calls for extended revaccination intervals prompted considerable debate in USA and internationally. Areas of concern include the amount of evidence to support prolonged immunity from various vaccines, the risk of poor responses in individual animals and the possible effects on population immunity. This review examines how the duration of immunity (DOI) to a vaccine is established in animals and humans. It reviews factors that can affect the DOI in an individual animal, including the types of immune defenses stimulated by the pathogen, and the vaccine, host factors such as age and the level of exposure to the pathogen. In addition, it examines DOI studies that were published for canine and feline core vaccines.

Keywords

vaccinesdogscatsduration of immunityvaccination interval
Type
Review Article
Information
Animal Health Research Reviews , Volume 11 , Issue 2 , December 2010 , pp. 165 - 190
Copyright
Copyright © Cambridge University Press 2010

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References

Abdelmagid, OY, Larson, L, Payne, L, Tubbs, A, Wasmoen, T and Schultz, R (2004). Evaluation of the efficacy and duration of immunity of a canine combination vaccine against virulent parvovirus, infectious canine hepatitis virus, and distemper virus experimental challenges. Veterinary Therapeutics: Research in Applied Veterinary Medicine 5: 173–186.Google ScholarPubMed
Ackermann, O and Dorr, W (1983). Prufung der schutzdauer gege die panleukopenie der katze. nach impfung mit Felidovac P. Die Blauen Hefte für den Tierarzt 66: 263–267.Google Scholar
Ada, G (2003). Progress towards achieving new vaccine and vaccination goals. Internal Medicine Journal 33: 297–304.Google Scholar
American Veterinary Medical Association (2007). Vaccination principles. Available at: http://www.avma.org/issues/policy/vaccination_principles.asp (accessed 20 August 2010).Google Scholar
Armengol, G, Ruiz, LM and Orduz, S (2004). The injection of plasmid DNA in mouse muscle results in lifelong persistence of DNA, gene expression, and humoral response. Molecular Biotechnology 27: 109–118.Google Scholar
Aubert, MF (1992). Practical significance of rabies antibodies in cats and dogs. Revue Scientifique et Technique (International Office of Epizootics) 11: 735–760.Google ScholarPubMed
Bahloul, C, Taieb, D, Diouani, MF, Ahmed, SB, Chtourou, Y, B'chir, BI, Kharmachi, H and Dellagi, K (2006). Field trials of a very potent rabies DNA vaccine which induced long lasting virus neutralizing antibodies and protection in dogs in experimental conditions. Vaccine 24: 1063–1072.CrossRefGoogle ScholarPubMed
Baker, JA, Robson, DS, Hildreth, B and Pakkala, B (1962). Breed response to distemper vaccination. Proceedings of the Animal Care Panel (U.S.) 11: 234–244.Google Scholar
Banerji, N, Kapur, V and Kanjilal, S (2007). Association of germ-line polymorphisms in the feline p53 gene with genetic predisposition to vaccine-associated feline sarcoma. Journal of Heredity 98: 421–427.CrossRefGoogle ScholarPubMed
Benson, MJ, Erickson, LD, Gleeson, MW and Noelle, RJ (2007). Affinity of antigen encounter and other early B-cell signals determine B-cell fate. Current Opinion in Immunology 19: 275–280.CrossRefGoogle ScholarPubMed
Bey, RF and Johnson, RC (1982). Immunogenicity and humoral and cell-mediated immune responses to leptospiral whole cell, outer envelope, and protoplasmic cylinder vaccines in hamsters and dogs. American Journal of Veterinary Research 43: 835–840.Google ScholarPubMed
Bohm, M, Thompson, H, Weir, A, Hasted, AM, Maxwell, NS and Herrtage, ME (2004). Serum antibody titres to canine parvovirus, adenovirus and distemper virus in dogs in the UK which had not been vaccinated for at least three years. The Veterinary Record 154: 457–463.CrossRefGoogle Scholar
Canadian Veterinary Medical Association (2007). Vaccination protocols for dogs and cats. Available at: http://canadianveterinarians.net/ShowText.aspx?ResourceID=832 (accessed 20 August 2010).Google Scholar
Carmichael, LE (1999). Canine viral vaccines at a turning point—a personal perspective. Advances in Veterinary Medicine 41: 289–307.Google Scholar
Carmichael, LE, Joubert, JC and Pollock, RV (1983). A modified live canine parvovirus vaccine. II. Immune response. The Cornell Veterinarian 73: 13–29.Google ScholarPubMed
Cliquet, F, Verdier, Y, Sagne, L, Aubert, M, Schereffer, JL, Selve, M, Wasniewski, M and Servat, A (2003). Neutralising antibody titration in 25,000 sera of dogs and cats vaccinated against rabies in France, in the framework of the new regulations that offer an alternative to quarantine. Revue Scientifique et Technique (International Office of Epizootics) 22: 857–866.Google Scholar
Coleman, PG and Dye, C (1996). Immunization coverage required to prevent outbreaks of dog rabies. Vaccine 14: 185–186.CrossRefGoogle ScholarPubMed
Cooper, PE, Chappius, G, Saint-Gerand, AL and Duret, C (1991). Comparaison de l'efficacite des differents vaccins du chien, utilises sous forme monovalente ou associee, par evaluation des responses serologiques et apres epreuves virulentes 12, 22 pet 26 mois apres vaccination. Bulletin Mensuel de la Société Vétérinaire Pratique de France 75: 131–132.Google Scholar
Coyne, MJ, Burr, JH, Yule, TD, Harding, MJ, Tresnan, DB and McGavin, D (2001a). Duration of immunity in cats after vaccination or naturally acquired infection. The Veterinary Record 149: 545–548.CrossRefGoogle ScholarPubMed
Coyne, MJ, Burr, JH, Yule, TD, Harding, MJ, Tresnan, DB and McGavin, D (2001b). Duration of immunity in dogs after vaccination or naturally acquired infection. The Veterinary Record 149: 509–515.CrossRefGoogle ScholarPubMed
Davidkin, I, Peltola, H, Leinikki, P and Valle, M (2000). Duration of rubella immunity induced by two-dose measles, mumps and rubella (MMR) vaccination. A 15-year follow-up in Finland. Vaccine 18: 3106–3112.CrossRefGoogle ScholarPubMed
Davis-Wurzler, GM (2006). Current vaccination strategies in puppies and kittens. The Veterinary Clinics of North America. Small Animal Practice 36: 607–640.CrossRefGoogle Scholar
Day, MJ (2007). Immune system development in the dog and cat. Journal of Comparative Pathology 137: S10–S15.CrossRefGoogle ScholarPubMed
Day, MJ, Horzinek, MC and Schultz, RD (2007). Guidelines for the vaccination of dogs and cats. Compiled by the Vaccination Guidelines Group (VGG) of the World Small Animal Veterinary Association (WSAVA). Journal of Small Animal Practice 48: 528–541.CrossRefGoogle ScholarPubMed
Dodds, WJ (2001). Vaccination protocols for dogs predisposed to vaccine reactions. Journal of the American Animal Hospital Association 37: 211–214.CrossRefGoogle ScholarPubMed
El-Kommonen, C, Sihvonen, L, Pekkanen, K, Rikula, U and Nuotio, L (1997). Outbreak of canine distemper in vaccinated dogs in Finland. The Veterinary Record 141: 380–383.CrossRefGoogle Scholar
Elston, T, Rodan, H, Flemming, D, Ford, RB, Hustead, DR, Richards, JR, Rosen, DK, Scherk-Nixon, MA and Scott, PW (1998). 1998 Report of the American Association of Feline Practitioners and Academy of Feline Medicine Advisory Panel on Feline Vaccines. Journal of the American Veterinary Medical Association 212: 227–241.CrossRefGoogle Scholar
Endsley, JJ, Roth, JA, Ridpath, J and Neill, J (2003). Maternal antibody blocks humoral but not T cell responses to BVDV. Biologicals 31: 123–125.CrossRefGoogle Scholar
Endsley, JJ, Ridpath, JF, Neill, JD, Sandbulte, MR and Roth, JA (2004). Induction of T lymphocytes specific for bovine viral diarrhea virus in calves with maternal antibody. Viral Immunology 17: 13–23.CrossRefGoogle ScholarPubMed
Fishman, B and Scarnell, J (1976). Persistence of protection after vaccination against infectious canine hepatitis virus (CAV/1). The Veterinary Record 99: 509.Google Scholar
Ford, RB (2001). Vaccines and vaccinations. The strategic issues. The Veterinary Clinics of North America. Small Animal Practice 31: 439–453.CrossRefGoogle Scholar
Franke, V and Danner, K (1990). Erfahrungen mit einem neuen Katzenschnupfen-panleukopenie-tollwut-kombinationsimostoff. Tierärztliche Praxis 18: 629–632.Google Scholar
Gaskell, RM, Gettinby, G, Graham, SJ and Skilton, D (2002). Veterinary Products Committee working group report on feline and canine vaccination. The Veterinary Record 150: 126–134.Google Scholar
Gaskell, RM, Dawson, S and Radford, AD (2006). Duration of immunity (DOI) –the regulatory issues. Veterinary Microbiology 117: 80–85.CrossRefGoogle ScholarPubMed
Gill, M, Srinivas, J, Morozov, I, Smith, J, Anderson, C, Glover, S, Champ, D and Chu, H (2004). Three-year duration of immunity for canine distemper, adenovirus, and parvovirus after vaccination with a multivalent canine vaccine. International Journal of Applied Research in Veterinary Medicine 2: 227–234.Google Scholar
Gore, TC, Lakshmanan, N, Duncan, KL, Coyne, MJ, Lum, MA and Sterner, FJ (2005). Three-year duration of immunity in dogs following vaccination against canine adenovirus type-1, canine parvovirus, and canine distemper virus. Veterinary Therapeutics: Research in Applied Veterinary Medicine 6: 5–14.Google ScholarPubMed
Gore, TC, Lakshmanan, N, Williams, JR, Jirjis, FF, Chester, ST, Duncan, KL, Coyne, MJ, Lum, MA and Sterner, FJ (2006). Three-year duration of immunity in cats following vaccination against feline rhinotracheitis virus, feline calicivirus, and feline panleukopenia virus. Veterinary Therapeutics: Research in Applied Veterinary Medicine 7: 213–222.Google ScholarPubMed
Greene, CE, Schultz, RD and Ford, RB (2001). Canine vaccination. The Veterinary Clinics of North America. Small Animal Practice 31: 473–92.CrossRefGoogle ScholarPubMed
Gumley, N (2000). Revaccination guidelines revisited. Canadian Veterinary Journal 41: 26–27.Google ScholarPubMed
Guris, D, McCready, J, Watson, JC, Atkinson, WL, Heath, JL, Bellini, WJ and Polloi, A (1996). Measles vaccine effectiveness and duration of vaccine-induced immunity in the absence of boosting from exposure to measles virus. The Pediatric Infectious Disease Journal 15: 1082–1086.CrossRefGoogle ScholarPubMed
Hammarlund, E, Lewis, MW, Hansen, SG, Strelow, LI, Nelson, JA, Sexton, GJ, Hanifin, JM and Slifka, MK (2003). Duration of antiviral immunity after smallpox vaccination. Nature Medicine 9: 1131–1137.CrossRefGoogle ScholarPubMed
Harbour, DA, Gunn-Moore, DA, Gruffydd-Jones, TJ, Caney, SM, Bradshaw, J, Jarrett, O and Wiseman, A (2002). Protection against oronasal challenge with virulent feline leukaemia virus lasts for at least 12 months following a primary course of immunisation with Leukocell 2 vaccine. Vaccine 20: 2866–2872.CrossRefGoogle ScholarPubMed
Hartman, EG, van Houten, M, Frik, JF and van der Donk, JA (1984). Humoral immune response of dogs after vaccination against leptospirosis measured by an IgM- and IgG-specific ELISA. Veterinary Immunology and Immunopathology 7: 245–254.CrossRefGoogle ScholarPubMed
Hendrick, MJ (1998). Historical review and current knowledge of risk factors involved in feline vaccine-associated sarcomas. Journal of the American Veterinary Medical Association 213: 1422–1423.CrossRefGoogle ScholarPubMed
HogenEsch, H, Thompson, S, Dunham, A, Ceddia, M and Hayek, M (2004). Effect of age on immune parameters and the immune response of dogs to vaccines: a cross-sectional study. Veterinary Immunology and Immunopathology 97: 77–85.Google Scholar
Hoover, EA, Mullins, JI, Chu, HJ and Wasmoen, TL (1995). Development and testing of an inactivated feline leukemia virus vaccine. Seminars in Veterinary Medicine and Surgery (Small Animal) 10: 238–243.Google Scholar
Hurley, KF and Sykes, JE (2003). Update on feline calicivirus: new trends. The Veterinary Clinics of North America. Small Animal Practice 33: 759–772.CrossRefGoogle Scholar
Hurley, KE, Pesavento, PA, Pedersen, NC, Poland, AM, Wilson, E and Foley, JE (2004). An outbreak of virulent systemic feline calicivirus disease. Journal of the American Veterinary Medical Association 224: 241–249.CrossRefGoogle ScholarPubMed
Jacobs, AA, Theelen, RP, Jaspers, R, Horspool, LJ, Sutton, D, Bergman, JG and Paul, G (2005). Protection of dogs for 13 months against Bordetella bronchiseptica and canine parainfluenza virus with a modified live vaccine. The Veterinary Record 157: 19–23.CrossRefGoogle ScholarPubMed
Johnson, RP and Povey, RC (1985). Vaccination against feline viral rhinotracheitis in kittens with maternally derived feline viral rhinotracheitis antibodies. Journal of the American Veterinary Medical Association 186: 149–152.Google Scholar
Jozwik, A, Frymus, T, Mizak, B and Rzezutka, A (2004). Antibody titres against canine distemper virus in vaccinated and unvaccinated dogs. Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health 51: 99–103.CrossRefGoogle ScholarPubMed
Kennedy, LJ, Carter, SD, Barnes, A, Bell, S, Bennett, D, Ollier, B and Thomson, W (1999). Interbreed variation of DLA-DRB1, DQA1 alleles and haplotypes in the dog. Veterinary Immunology and Immunopathology 69: 101–111.CrossRefGoogle ScholarPubMed
Kennedy, LJ, Lunt, M, Barnes, A, McElhinney, L, Fooks, AR, Baxter, DN and Ollier, WE (2007). Factors influencing the antibody response of dogs vaccinated against rabies. Vaccine 25: 8500–8507.Google Scholar
Klaasen, HL, Molkenboer, MJ, Vrijenhoek, MP and Kaashoek, MJ (2003). Duration of immunity in dogs vaccinated against leptospirosis with a bivalent inactivated vaccine. Veterinary Microbiology 95: 121–132.CrossRefGoogle ScholarPubMed
Klingborg, DJ, Hustead, DR, Curry-Galvin, EA, Gumley, NR, Henry, SC, Bain, FT, Paul, MA, Boothe, DM, Blood, KS, Huxsoll, DL, Reynolds, DL, Riddell, MG Jr, Reid, JS and Short, CR (2002). AVMA Council on Biologic and Therapeutic Agents' report on cat and dog vaccines. Journal of the American Veterinary Medical Association 221: 1401–1407.CrossRefGoogle Scholar
Kolar, JR and Rude, TA (1981). Duration of immunity in cats inoculated with a commercial feline pneumonitis vaccine. Veterinary Medicine, Small Animal Clinician 76: 1171–1173.Google ScholarPubMed
Kruth, SA and Ellis, JA (1998). Vaccination of dogs and cats: general principles and duration of immunity. The Canadian Veterinary Journal 39: 423–426.Google ScholarPubMed
Lakshmanan, N, Gore, TC, Duncan, KL, Coyne, MJ, Lum, MA and Sterner, FJ (2006). Three-year rabies duration of immunity in dogs following vaccination with a core combination vaccine against canine distemper virus, canine adenovirus type-1, canine parvovirus, and rabies virus. Veterinary Therapeutics: Research in Applied Veterinary Medicine 7: 223–231.Google Scholar
Lappin, MR, Andrews, J, Simpson, D and Jensen, WA (2002). Use of serologic tests to predict resistance to feline herpesvirus 1, feline calicivirus, and feline parvovirus infection in cats. Journal of the American Veterinary Medical Association 220: 38–42.Google Scholar
Larson, RL (1996). Immunologic principles and immunization strategy. Compendium on Continuing Education for the Practicing Veterinarian 18: 963–970.Google Scholar
Larson, LJ and Schultz, RD (1997). Comparison of selected canine vaccines for their ability to induce protective immunity against canine parvovirus infection. American Journal of Veterinary Research 58: 360–363.CrossRefGoogle ScholarPubMed
Larson, LJ and Schultz, RD (2007). Three-year duration of immunity in dogs vaccinated with a canarypox-vectored recombinant canine distemper virus vaccine. Veterinary Therapeutics: Research in Applied Veterinary Medicine 8: 101–106.Google ScholarPubMed
Larson, LJ and Schultz, RD (2008). Do two current canine parvovirus type 2 and 2b vaccines provide protection against the new type 2c variant? Veterinary Therapeutics: Research in Applied Veterinary Medicine 9: 94–101.Google ScholarPubMed
LaFleur, RL, Callister, SM, Dant, JC, Jobe, DA, Lovrich, SD, Warner, TF, Wasmoen, TL and Schell, RF (2010). One-year duration of immunity induced by vaccination with a canine Lyme disease bacterin. Clinical and Vaccine Immunology 17: 870–874.CrossRefGoogle ScholarPubMed
Lehar, C, Jayappa, H, Erskine, J, Brown, A, Sweeney, D and Wassmoen, T (2008). Demonstration of 1-year duration of immunity for attenuated Bordetella bronchiseptica vaccines in dogs. Veterinary Therapeutics: Research in Applied Veterinary Medicine 9: 257–262.Google ScholarPubMed
Longini, IM Jr, Halloran, ME, Haber, M and Chen, RT (1993). Measuring vaccine efficacy from epidemics of acute infectious agents. Statistics in Medicine 12: 249–263.CrossRefGoogle ScholarPubMed
Mansfield, KL, Burr, PD, Snodgrass, DR, Sayers, R and Fooks, AR (2004). Factors affecting the serological response of dogs and cats to rabies vaccination. The Veterinary Record 154: 423–426.CrossRefGoogle ScholarPubMed
McCaw, DL, Thompson, M, Tate, D, Bonderer, A and Chen, YJ (1998). Serum distemper virus and parvovirus antibody titers among dogs brought to a veterinary hospital for revaccination. Journal of the American Veterinary Medical Association 213: 72–75.Google Scholar
McKelvey, D (1998). Vaccine protocol change deemed premature. Canadian Veterinary Journal 39: 203–206.Google Scholar
Meyer, EK (2001). Vaccine-associated adverse events. The Veterinary Clinics of North America. Small Animal Practice 31: 493–514.CrossRefGoogle ScholarPubMed
Milward, F (1997). Efficacy of recombinant Lyme disease vaccination. International Forum on Ticks and Tickborne Diseases. Compendium on Continuing Education for the Practicing Veterinarian 19(Suppl): 49–51.Google Scholar
Minke, JM, Bey, R, Tronel, JP, Latour, S, Colombet, G, Yvorel, J, Cariou, C, Guiot, AL, Cozette, V and Guigal, PM (2009). Onset and duration of protective immunity against clinical disease and renal carriage in dogs provided by a bivalent inactivated leptospirosis vaccine. Veterinary Microbiology 137: 137–145.CrossRefGoogle ScholarPubMed
Moore, GE, Guptill, LF, Ward, MP, Glickman, NW, Faunt, KK, Lewis, HB and Glickman, LT (2005). Adverse events diagnosed within three days of vaccine administration in dogs. Journal of the American Veterinary Medical Association 227: 1102–8.CrossRefGoogle ScholarPubMed
Moore, GE, DeSantis-Kerr, AC, Guptill, LF, Glickman, NW, Lewis, HB and Glickman, LT (2007). Adverse events after vaccine administration in cats: 2,560 cases (2002–2005). Journal of the American Veterinary Medical Association 231: 94–100.Google Scholar
Mouzin, DE, Lorenzen, MJ, Haworth, JD and King, VL (2004a). Duration of serologic response to five viral antigens in dogs. Journal of the American Veterinary Medical Association 224: 55–60.CrossRefGoogle ScholarPubMed
Mouzin, DE, Lorenzen, MJ, Haworth, JD and King, VL (2004b). Duration of serologic response to three viral antigens in cats. Journal of the American Veterinary Medical Association 224: 61–66.Google Scholar
Munday, JS, Stedman, NL and Richey, LJ (2003). Histology and immunohistochemistry of seven ferret vaccination-site fibrosarcomas. Veterinary Pathology 40: 288–293.CrossRefGoogle ScholarPubMed
Naiman, BM, Alt, D, Bolin, CA, Zuerner, R and Baldwin, CL (2001). Protective killed Leptospira borgpetersenii vaccine induces potent Th1 immunity comprising responses by CD4 and gammadelta T lymphocytes. Infection and Immunity 69: 7550–7558.Google Scholar
Olson, P, Klingeborn, B and Hedhammar, A (1988). Serum antibody response to canine parvovirus, canine adenovirus-1, and canine distemper virus in dogs with known status of immunization: study of dogs in Sweden. American Journal of Veterinary Research 49: 1460–1466.Google ScholarPubMed
Olson, P, Hedhammar, A and Klingeborn, B (1996). Canine parvovirus infection, canine distemper and infectious canine hepatitis: inclination to vaccinate and antibody response in the Swedish dog population. Acta Veterinaria Scandinavica 37: 433–443.CrossRefGoogle ScholarPubMed
Olson, P, Finnsdottir, H, Klingeborn, B and Hedhammar, A (1997). Duration of antibodies elicited by canine distemper virus vaccinations in dogs. The Veterinary Record 141: 654–645.Google Scholar
Ottiger, HP, Neimeier-Förster, M, Stärk, KD, Duchow, K and Bruckner, L (2006). Serological responses of adult dogs to revaccination against distemper, parvovirus and rabies. The Veterinary Record 159: 7–12.CrossRefGoogle ScholarPubMed
Pardo, ID, Johnson, GC and Kleiboeker, SB (2005). Phylogenetic characterization of canine distemper viruses detected in naturally infected dogs in North America. Journal of Clinical Microbiology 43: 5009–5017.CrossRefGoogle ScholarPubMed
Paul, MA, Carmichael, LE, Childers, H, Cotter, S, Davidson, A, Ford, R, Hurley, KF, Roth, JA, Schultz, RD, Thacker, E and Welborn, L (2006). 2006 AAHA canine vaccine guidelines. Journal of the American Animal Hospital Association 42: 80–89.CrossRefGoogle ScholarPubMed
Piercy, SE (1961). An appraisal of the value and method of use of living attenuated canine distemper vaccines. The Veterinary Record 73: 944–949.Google Scholar
Povey, RC, Koonse, H and Hays, MB (1980). Immunogenicity and safety of an inactivated vaccine for the prevention of rhinotracheitis, caliciviral disease, and panleukopenia in cats. Journal of the American Veterinary Medical Association 177: 347–350.Google ScholarPubMed
Povey, RC, Carmen, S and Evert, E (1983). The duration of immunity to an inactivated adjuvanted canine parvovirus vaccine. The Canadian Veterinary Journal 24: 245–248.Google Scholar
Prydie, J (1966). Persistence of antibodies following vaccination against canine distemper and the effect of revaccination. The Veterinary Record 78: 486–488.CrossRefGoogle ScholarPubMed
Radford, AD, Coyne, KP, Dawson, S, Porter, CJ and Gaskell, RM (2007). Feline calicivirus. Veterinary Research 38: 319–335.CrossRefGoogle ScholarPubMed
Radford, AD, Addie, D, Belák, S, Boucraut-Baralon, C, Egberink, H, Frymus, T, Gruffydd-Jones, T, Hartmann, K, Hosie, MJ, Lloret, A, Lutz, H, Marsilio, F, Pennisi, MG, Thiry, E, Truyen, U and Horzinek, MC (2009). Feline calicivirus infection. ABCD guidelines on prevention and management. Journal of Feline Medicine and Surgery 11: 556–564.CrossRefGoogle ScholarPubMed
Richards, J and Rodan, I (2001). Feline vaccination guidelines. The Veterinary Clinics of North America. Small Animal Practice 31: 455–472.CrossRefGoogle ScholarPubMed
Richards, JR, Elston, TH, Ford, RB, Gaskell, RM, Hartmann, K, Hurley, KF, Lappin, MR, Levy, JK, Rodan, I, Scherk, M, Schultz, RD and Sparkes, AH (2006). The 2006 American Association of Feline Practitioners Feline Vaccine Advisory Panel report. Journal of the American Veterinary Medical Association 229: 1405–1441.CrossRefGoogle Scholar
Rife, SU, Marquez, MG, Escalante, A and Velich, T (1990). The effect of testosterone on the immune response. 1. Mechanism of action on antibody-forming cells. Immunological Investigations 19: 259–270.Google Scholar
Rikula, U, Nuotio, L and Sihvonen, L (2000). Canine distemper virus neutralising antibodies in vaccinated dogs. The Veterinary Record 147: 598–603.CrossRefGoogle ScholarPubMed
Robson, DS (1966). Comments on duration of vaccination immunity. Journal of the American Veterinary Medical Association 149: 704–706.Google ScholarPubMed
Rouderfer, V, Becker, NG and Hethcote, HW (1994). Waning immunity and its effects on vaccination schedules. Mathematical Biosciences 124: 59–82.Google Scholar
Scarlett, JM and Pollock, RV (1991). Year two of follow-up evaluation of a randomized, blind field trial of a commercial feline leukemia virus vaccine. Journal of the American Veterinary Medical Association 199: 1431–1432.CrossRefGoogle ScholarPubMed
Schultz, RD (2006). Duration of immunity for canine and feline vaccines: A review. Veterinary Microbiology 117: 75–79.CrossRefGoogle ScholarPubMed
Schuurs, AH and Verheul, HA (1990). Effects of gender and sex steroids on the immune response. Journal of Steroid Biochemistry 35: 157–172.CrossRefGoogle ScholarPubMed
Scott, FW (1977). Evaluation of a feline viral rhinotracheitis-feline calicivirus disease vaccine. American Journal of Veterinary Research 38: 229–234.Google ScholarPubMed
Scott, FW and Geissinger, C (1997). Duration of immunity in cats vaccinated with an inactivated feline panleukopenia, herpesvirus, and calicivirus vaccine. Feline Practice 25: 12–19.Google Scholar
Scott, FW and Geissinger, CM (1999). Long-term immunity in cats vaccinated with an inactivated trivalent vaccine. American Journal of Veterinary Research 60: 652–658.CrossRefGoogle ScholarPubMed
Sikes, RK, Peacock, GV, Acha, P, Arko, RJ and Dierks, R (1971). Rabies vaccines: duration-of-immunity study in dogs. Journal of the American Veterinary Medical Association 159: 1491–1499.Google ScholarPubMed
Spibey, N, Greenwood, NM, Sutton, D, Chalmers, WS and Tarpey, I (2008). Canine parvovirus type 2 vaccine protects against virulent challenge with type 2c virus. Veterinary Microbiology 128: 48–55.CrossRefGoogle ScholarPubMed
Stein, JE, Radecki, SV and Lappin, MR (2003). Efficacy of Giardia vaccination in the treatment of giardiasis in cats. Journal of the American Veterinary Medical Association 222: 1548–1551.CrossRefGoogle ScholarPubMed
Strasser, A, May, B, Teltscher, A, Wistrela, E and Niedermuller, H (2003). Immune modulation following immunization with polyvalent vaccines in dogs. Veterinary Immunology and Immunopathology 94: 113–21.CrossRefGoogle ScholarPubMed
Thiry, E and Horzinek, MC (2007). Vaccination guidelines: a bridge between official requirements and the daily use of vaccines. Revue Scientifique et Technique (International Office of Epizootics) 26: 511–517.Google ScholarPubMed
Thiry, E, Addie, D, Belák, S, Boucraut-Baralon, C, Egberink, H, Frymus, T, Gruffydd-Jones, T, Hartmann, K, Hosie, MJ, Lloret, A, Lutz, H, Marsilio, F, Pennisi, MG, Radford, AD, Truyen, U and Horzinek, MC (2009). Feline herpesvirus infection. ABCD guidelines on prevention and management. Journal of Feline Medicine and Surgery 11: 547–555.Google Scholar
Tizard, I and Ni, Y (1998). Use of serologic testing to assess immune status of companion animals. Journal of the American Veterinary Medical Association 213: 54–60.CrossRefGoogle ScholarPubMed
Truyen, U, Addie, D, Belák, S, Boucraut-Baralon, C, Egberink, H, Frymus, T, Gruffydd-Jones, T, Hartmann, K, Hosie, MJ, Lloret, A, Lutz, H, Marsilio, F, Pennisi, MG, Radford, AD, Thiry, E and Horzinek, MC (2009). Feline panleukopenia. ABCD guidelines on prevention and management. Journal of Feline Medicine and Surgery 11: 538–546.CrossRefGoogle ScholarPubMed
Twark, L and Dodds, WJ (2000). Clinical use of serum parvovirus and distemper virus antibody titers for determining revaccination strategies in healthy dogs. Journal of the American Veterinary Medical Association 217: 1021–1024.CrossRefGoogle ScholarPubMed
Verthelyi, D and Klinman, DM (2000). Sex hormone levels correlate with the activity of cytokine-secreting cells in vivo. Immunology 100: 384–390.Google Scholar
Wallace, BL and McMillen, JK (1985). An inactivated canine parvovirus vaccine: duration of immunity and effectiveness in presence of maternal antibody. Canine Practice 12: 14–19.Google Scholar
Wasmoen, T, Chu, H-J, Chavez, L and Acree, W (1992). Demonstration of one year duration of immunity for an inactivated feline Chlamydia psittaci vaccine. Feline Practice 20: 13–16.Google Scholar
Wendelboe, AM, Van Rie, A, Salmaso, S and Englund, JA (2005). Duration of immunity against pertussis after natural infection or vaccination. The Pediatric Infectious Disease Journal 24: S58–S61.CrossRefGoogle ScholarPubMed