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Cryptosporidium parvum and mucosal immunity in neonatal cattle

Published online by Cambridge University Press:  28 February 2007

Carol R. Wyatt
Carol R. Wyatt*
Affiliation:
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, USA
*
P.O. Box 647040, Washington State University, Pullman, WA 99164–7040, USA
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Abstract

Cryptosporidium parvum is an important zoonotic protozoan pathogen that causes acute infection and self-limiting gastrointestinal disease in neonatal calves. There are currently no consistently effective antimicrobials available to control cryptosporidiosis. Therefore, immunotherapeutic and vaccination protocols offer the greatest potential for long-term control of the disease. In order to devise effective control measures, it is important to better define mucosal immunity to C. parvum in young calves. This review summarizes the information that has accumulated over the last decade which helps to define the intestinal mucosal immune system in neonatal calves, and the events that occur in the intestinal mucosa after infection by C. parvum.

Type
Research Article
Information
Animal Health Research Reviews , Volume 1 , Issue 1 , June 2000 , pp. 25 - 34
Copyright
Copyright © CAB International 2000

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