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BVD control in Europe: current status and perspectives

Published online by Cambridge University Press:  28 February 2007

Volker Moennig ,
Hans Houe  and
Ann Lindberg
Volker Moennig*
Affiliation:
Institute of Virology, School of Veterinary Medicine, D-30559 Hannover, Germany, ([email protected])
Hans Houe
Affiliation:
Department of Large Animal Sciences, Section for Veterinary Epidemiology, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark, ([email protected])
Ann Lindberg
Affiliation:
Swedish Dairy Association, Research & Development, SE-750 07 Uppsala, Sweden, ([email protected])
*
*Corresponding author.
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Abstract

For several decades after the first description of bovine viral diarrhea and its causative agent (BVDV) the economic impact of the infection was underestimated and in addition there were no suitable diagnostics and procedures for a systematic control at hand. Today, there are several estimates on the real economic impact of the infection and during the last 15 years the serological and virological laboratory diagnosis of BVDV infections has improved. Also, successful procedures aimed at eradicating BVDV infections by using a strict test and removal policy for animals persistently infected (PI) with BVDV accompanied by movement restrictions for infected herds have been implemented in the Scandinavian countries. The success of these efforts has encouraged other European countries to follow the same procedures. However, the Scandinavian control strategy might—for a number of reasons—not be acceptable for all European countries. In such cases, the test and removal strategy, with its fundamental elements of biosecurity, removal of PI animals and monitoring of herd status, in combination with systematic vaccination, might be an acceptable compromise. The impact of the BVDV-free status of regions and nations on international trade is not yet clear. In any case, biosecurity measures will be of utmost importance for individual control programs as well as multiple control programs to co-exist in Europe.

Keywords

bovine viral diarrheacontrol strategyEuropevaccination
Type
Research Article
Information
Animal Health Research Reviews , Volume 6 , Issue 1 , June 2005 , pp. 63 - 74
Copyright
Copyright © CAB International 2005

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References

Andre, FE (2003). Vaccinology: past achievements, present roadblocks and future promises. Vaccine 21: 593–595.CrossRefGoogle ScholarPubMed
Baker, JC (1995). The clinical manifestations of bovine viral diarrhea infection. Veterinary Clinics of North America—Food Animal Practice 11: 425–445.CrossRefGoogle ScholarPubMed
Beer, M, Wolf, G, Pichler, J, Wolfmeyer, A and Kaaden, OR (1997). Cytotoxic T-lymphocyte responses in cattle infected with bovine viral diarrhea virus. Veterinary Microbiology 58: 9–22.CrossRefGoogle ScholarPubMed
Bendfeldt, S, Grummer, B, Haas, L, Staubach, C, Moennig, V and Liess, B (2004). [Seroprevalences in four different counties in Lower Saxony and the relevance for the control strategy]. Tierärztliche Umschau 59: 499–507.Google Scholar
Bennett, RM and Done, JT (1986). Control of BVDV: a case for social cost—benefit analysis? In: Proceedings of the Meeting of the Society of Veterinary Epidemiology and Preventive Medicine, 2–4 April 1986 Edinburgh, pp 54–65.Google Scholar
Bennett, RM (1992). Case-study of a simple decision support system to aid livestock disease control decisions. Agricultural Systems 38: 111–129.CrossRefGoogle Scholar
Bitsch, V and Ronsholt, L (1995). Control of bovine viral diarrhea virus infection without vaccines. Veterinary Clinics of North America—Food Animal Practice 11: 627–640.CrossRefGoogle ScholarPubMed
Bolin, SR and Ridpath, JF (1995). Assessment of Protection from Systemic Infection Or disease afforded by low to intermediate titers of passively acquired neutralizing antibody against bovine viral diarrhea virus in calves. American Journal of Veterinary Research 56: 755–759.CrossRefGoogle ScholarPubMed
Brownlie, J, Clarke, MC and Howard, CJ (1984). Experimental production of fatal mucosal disease in cattle. Veterinary Record 114: 535–536.CrossRefGoogle ScholarPubMed
Carman, S, Van Dreumel, T, Ridpath, J, Hazlett, M, Alves, D, Dubovi, E, Tremblay, R, Bolin, S, Godkin, A and Anderson, N (1998). Severe acute bovine viral diarrhea in Ontario, 1993–1995. Journal of Veterinary Diagnostic Investigation 10: 27–35.CrossRefGoogle ScholarPubMed
Chesney, MA, Chambers, DB and Kahn, JO (1997). Risk behavior for HIV infection in participants in preventive HIV vaccine trials: a cautionary note. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 16: 266–271.CrossRefGoogle ScholarPubMed
Coggins, L, Gillespie, JH, Robson, DS, Thompson, JD, Phillips, WV, Wagner, WC and Baker, JA (1961). Attenuation of virus diarrhea virus (strain oregon C24V) for vaccine purposes. Cornell Veterinarian 51: 539–545.Google ScholarPubMed
Collen, T, Carr, V, Parsons, K, Charleston, B and Morrison, WI (2002). Analysis of the repertoire of cattle CD4(+) T cells reactive with bovine viral diarrhoea virus. Veterinary Immunology Immunopatholology 87: 235–238.CrossRefGoogle ScholarPubMed
Cortese, VS, West, KH, Hassard, LE, Carman, S and Ellis, JA (1998). Clinical and immunologic responses of vaccinated and unvaccinated calves to infection with a virulent type-II isolate of bovine viral diarrhea virus. Journal of the American Veterinary Medical Association 213: 1312–1319.CrossRefGoogle ScholarPubMed
Done, JT, Terlecki, S, Richardson, C, Harkness, JW, Sands, JJ, Patterson, DS, Sweasey, D, Shaw, IG, Winkler, CE and Duffell, SJ (1980). Bovine virus diarrhoea—mucosal disease virus: pathogenicity for the fetal calf following maternal infection. Veterinary Record 106: 473–479.CrossRefGoogle ScholarPubMed
Drew, TW, Yapp, F and Paton, DJ (1999). The detection of bovine viral diarrhoea virus in bulk milk samples by the use of a single-tube RT-PCR. Veterinary Microbiology 64: 145–154.CrossRefGoogle ScholarPubMed
Ersbøll, AK and Stryhn, H (2000). Epidemiological modeling of infectious disease in animals: bovine virus diarrhoea in Danish dairy herds. In: Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics (ISVEE), 6–11, August 2000, Breckenridge, Colorado, USA, pp. 520–522.Google Scholar
Ersbøll, AK, Ersbøll, BK, Houe, H, Alban, L, Stryhn, H and Kjeldsen, AM (2005). Spatial modelling of spread of bovine virus diarrhoea between neighbouring cattle herds. Preventive Veterinary Medicine: submitted for publication.Google Scholar
Ferrari, G, Scicluna, MT, Bonvicini, D, Gobbi, C, Verita, D F Valentini, A and Autorino, GL (1999). Bovine virus diarrhoea (BVD) control programme in an area in the Rome province (Italy). Veterinary Microbiology 64: 237–245.CrossRefGoogle Scholar
Frey, HR, Flebbe, U and Liess, B (1996). [Prevalence and clinical symptoms of persistent BVD-virus infection in cattle herds of Lower Saxony]. Der Praktische Tierarzt 77: 49–52.Google Scholar
Frey, HR, Eicken, K, Grummer, B, Kenklies, S, Oguzoglu, TC and Moennig, V (2002). Foetal protection against bovine virus diarrhoea virus after two-step vaccination. Journal of Veterinary Medicine B 49: 489–493.CrossRefGoogle ScholarPubMed
Fritzemeier, J, Haas, L, Liebler, E, Moennig, V and Greiser-Wilke, I (1997). The development of early vs. late onset mucosal disease is a consequence of two different pathogenic mechanisms. Archives of Virology 142: 1335–1350.CrossRefGoogle ScholarPubMed
Fulton, RW, Saliki, JT, Burge, LJd'Offay, JM, Bolin, SR, Maes, RK, Baker, JC and Frey, ML (1997). Neutralizing antibodies to type 1 and 2 bovine viral diarrhea viruses: detection by inhibition of viral cytopathology and infectivity by immunoperoxidase assay. Clinical and Diagnostic Laboratory Immunology 4: 380–383.CrossRefGoogle ScholarPubMed
Gillespie, JH, Baker, JA and McEntee, K (1960). A cytopathogenic strain of virus diarrhea virus. Cornell Veterinarian 50: 73–79.Google ScholarPubMed
Graham, DA, Calvert, V, Mooney, J, Crawford, J and Clery, D (2004). Birth of persistently infected calves in two herds using inactivated BVDV vaccines. In: Proceedings of the 2nd European Symposium on BVDV Control, 20–22 October 2004, Oporto, Portugal, p. 87.Google Scholar
Grooms, DL (2004). Reproductive consequences of infection with bovine viral diarrhea virus. Veterinary Clinics of North America—Food Animal Practice 20: 5–19.CrossRefGoogle ScholarPubMed
Gunn, GJ and Stott, AW (1999). Economic losses, epidemiology and eradication of bovine viral diarrhea in Scotland. In: European Society for Veterinary Virology, 4th Pestivirus Meeting, 15–19 March 1999, Giessen, Germany, Abstracts pp. S1–S8.Google Scholar
Gunn, G and Saatkamp, H (2005). Assessing economic and social pressure for the control of bovine viral diarrhoea virus Preventive Veterinary Medicine submitted for publication.CrossRefGoogle ScholarPubMed
Harkness, JW (1987). [The control of bovine virus diarrhoea virus infection]. Annales de Recherche Vétérinaire 18: 167–174.Google Scholar
Houe, H (1992). Serological analysis of a small herd sample to predict presence or absence of animals persistently infected with bovine viral diarrhoea virus (BVDV) in dairy herds. Research in Veterinary Science 53: 320–323.Google ScholarPubMed
Houe, H, Pedersen, KM and Meyling, A (1993). A computerized spread sheet model for calculating total annual national losses due to bovine virus diarrhoea virus (BVDV) infection in dairy herds and sensitivity analysis of selected parameters. In: Edwards, S., (ed.). Proceedings of the Second Symposium on Ruminant Pestiviruses, 1–3 October 1992, Annecy, France, pp. 179–184.Google Scholar
Houe, H, Lloyd, JW and Baker, JC (1994). Decision tree analysis of control strategies in Danish dairy herds with outbreaks of mucosal disease. Preventive Veterinary Medicine 21: 133–146.CrossRefGoogle Scholar
Houe, H (1995). Epidemiology of bovine viral diarrhea virus. Veterinary Clinics of North America—Food Animal Practice 11: 521–548.CrossRefGoogle ScholarPubMed
Houe, H (1999). Epidemiological features and economical importance of bovine virus diarrhoea virus (BVDV). Veterinary Microbiology 64: 89–107.CrossRefGoogle ScholarPubMed
Houe, H (2003). Economic impact of BVDV infections in dairies. Biologicals 31: 137–143.CrossRefGoogle ScholarPubMed
Hult, L and Lindberg, A (2005). BVD-eradication in Sweden—the goal in sight Preventive Veterinary Medicine Preventive Veterinary Medicine.Google Scholar
Joly, A, Beaudeau, F and Fourichon, C (2005). Description and first results of a BVDV control scheme in Bretagne (Western France) Preventive Veterinary Medicine: submitted for publication.CrossRefGoogle Scholar
Kelling, CL (2004). Evolution of bovine viral diarrhea virus vaccines. Veterinary Clinics of North America—Food Animal Practice 20: 115–129.CrossRefGoogle ScholarPubMed
Kendrick, JW (1971). Bovine viral diarrhea—mucosal disease virus infection in pregnant cows. American Journal of Veterinary Research 32: 533–544.Google ScholarPubMed
Liess, B, Orban, S, Frey, HR, Trautwein, G, Wiefel, W and Blindow, H (1984). [Studies on transplacental transmissibility of a bovine virus diarrhoea (BVD) vaccine virus in cattle. II. Inoculation of pregnant cows without detectable neutralizing antibodies to BVD virus 90–229 days before parturition (51st to 190th day of gestation)]. Zentralblatt Veterinärmedizin B 31: 669–681.CrossRefGoogle ScholarPubMed
Lindberg, A (1996). Regionalised eradication of bovine viral diarrhoea virus in Sweden –an approach complementary to the current control scheme. In: Society of Veterinary Epidemiology and Preventive Medicine: Conference Proceedings, 27–29 March 1996, Glasgow, Scotland, pp. 146–156.Google Scholar
Lindberg, A (2004). The Nordic eradication programmes on bovine viral diarrhoea virus-their success and future. Cattle Practice 12: 3–5.Google Scholar
Lindberg, A and Houe, H (2005). Characteristics in the epidemiology of bovine viral diarrhea virus (BVDV) of relevance to control Preventive Veterinary Medicine: submitted for publication.CrossRefGoogle ScholarPubMed
Lindberg, ALE and Alenius, S (1999). Principles for eradication of bovine viral diarrhoea virus (BVDV) infections in cattle populations. Veterinary Microbiology 64: 197–222.CrossRefGoogle ScholarPubMed
Löhr, BI, Frey, HR, Moennig, V and Greiser-Wilke, I (1998). Experimental induction of mucosal disease: consequences of superinfection of persistently infected cattle with different strains of cytopathogenic bovine viral diarrhea virus. Archives of Virology 143: 667–679.CrossRefGoogle Scholar
Luzzago, C, Frigerio, M and Zecconi, A (2004). BVD control program in Lecco and Como provinces (Italy): herd risk categories to modulate interventions. In: Proceedings of the 2nd European Symposium on BVDV Control, 20–22 October 2004, Oporto, Portugal, p. 100.Google Scholar
McClurkin, AW, Littledike, ET, Cutlip, RC, Frank, GH, Coria, MF and Bolin, SR (1984). Production of cattle immunotolerant to bovine viral diarrhea virus. Canadian Journal of Comparative Medicine 48: 156–161.Google ScholarPubMed
Moen, A, Sol, J and Sampimon, OC (2005). Sero-conversion in the absence of a PI animal Preventive Veterinary Medicine: submitted for publication.Google Scholar
Moennig, V, Eicken, K, Flebbe, U, Frey, HR, Grummer, B, Haas, L, Greiser-Wilke, I and Liess, B (2005). Implementation of two-step vaccination in the control of BVD. Preventive Veterinary Medicine: submitted for publication.CrossRefGoogle ScholarPubMed
Müller, T, Bätza, HJ, Schlüter, H, Conraths, FJ and Mettenleiter, TC (2003). Eradication of Aujeszky's disease in Germany. Journal of Veterinary Medicine, B Infectious Diseases and Veterinary Public Health 50: 207–213.CrossRefGoogle ScholarPubMed
Niskanen, R (1993). Relationship between the levels of antibodies to bovine viral diarrhoea virus in bulk tank milk and the prevalence of cows exposed to the virus. Veterinary Record 133: 341–344.CrossRefGoogle ScholarPubMed
Niskanen, R and Lindberg, A (2003). Transmission of bovine viral diarrhoea virus by unhygienic vaccination procedures, ambient air, and from contaminated pens. Veterinary Journal 165: 125–130.CrossRefGoogle ScholarPubMed
Nyberg, O, Østerås, O and Plym Forshell, K (2004). Eradication of BVDV-infection in Norwegian cattle 1992–2003—a success story. In: Proceedings of the 2nd European Symposium on BVDV Control, 20–22 October 2004, Oporto, Portugal, p. 40.Google Scholar
Oguzoglu, TC, Frey, HR, Eicken, K, Grummer, B, Liess, B and Moennig, V (2003). [Kinetics and persistence of neutralizing antibodies against bovine viral diarrhea virus-1 and -2 and border disease virus after two step vaccination of cattle]. Deutsche Tierärztliche Wochenschrift 110: 14–17.Google ScholarPubMed
Olafson, R, MacCallum, AD and Fox, FH (1946). An apparently new transmissible disease of cattle. Cornell Veterinarian 36: 205–213.Google ScholarPubMed
Orban, S, Liess, B, Hafez, SM, Frey, HR, Blindow, H and Sasse-Patzer, B (1983). Studies on transplacental transmissibility of a bovine virus diarrhoea (BVD) vaccine virus. I. Inoculation of pregnant cows 15 to 90 days before parturition (190th to 265th day of gestation). Zentralblatt Veterinärmedizin. B 30: 619–634.CrossRefGoogle ScholarPubMed
O'Rourke, K (2002). BVDV: 40 years of effort and the disease still has a firm hold. Journal of the American Veterinary Medical Association 220: 1770–1773.Google Scholar
Pasman, EJ, Dijkhuizen, AA and Wentink, GH (1994). A state-transition model to simulate the economics of bovine virus diarrhoea control. Preventive Veterinary Medicine 20: 269–277.CrossRefGoogle Scholar
Pritchard, G, Borland, ED, Wood, L and Pritchard, DG (1989). Severe disease in a dairy herd associated with acute infection with bovine virus diarrhoea virus, Leptospira hardjo and Coxiella burnetii. Veterinary Record 124: 625–629.CrossRefGoogle Scholar
Quaife, T (1996). Improper vaccination compounds BVD problem. Dairy Herd Management 33: 12–16.Google Scholar
Ramsey, FK and Chivers, WH (1953). Mucosal disease of cattle. North American Veterinarian 34: 629–633.Google Scholar
Rebhun, WC, French, TW, Perdrizet, JA, Dubovi, EJ and Karcher, LF (1989). Thrombocytopenia associated with acute bovine virus diarrhea infection in cattle. Journal of Veterinary Internal Medicine 3: 42–46.CrossRefGoogle ScholarPubMed
Ridpath, JF, Bolin, SR and Dubovi, EJ (1994). Segregation of bovine viral diarrhea virus into genotypes. Virology 205: 66–74.CrossRefGoogle ScholarPubMed
Rikula, U, Aaltonen, T and Ruoho, O (2005). BVD control in Finland 1998–2003 based on annual screening. Preventive Veterinary Medicine: submitted for publication.Google Scholar
Roeder, PL and Taylor, WP (2002). Rinderpest. Veterinary Clinics of North America—Food Animal Practice 18: 515–547.CrossRefGoogle ScholarPubMed
Rossmanith, W, Vilcek, S, Wenzl, H, Rossmanith, E, Loitsch, A, Durkovic, B, Strojny, L and Paton, DJ (2001). Improved antigen and nucleic acid detection in a bovine virus diarrhoea eradication program. Veterinary Microbiology 81: 207–218.CrossRefGoogle Scholar
Rossmanith, W, Janacek, R and Wilhelm, E (2005). Control of BVDV—infection on common grassland—The key for successful BVDV-eradication. Preventive Veterinary Medicine: submitted for publication.CrossRefGoogle ScholarPubMed
Roth, JA and Kaeberle, ML (1983). Suppression of neutrophil and lymphocyte function induced by a vaccinal strain of bovine viral diarrhea virus with and without the administration of ACTH. American Journal of Veterinary Research 44: 2366–2372.Google ScholarPubMed
Sandvik, T (2004). Progress of control and prevention programs for bovine viral diarrhea virus in Europe. Veterinary Clinics of North America—Food Animal Practice 20: 151–169.CrossRefGoogle ScholarPubMed
Santarossa, JM, Stott, AW, Humphry, RW and Gunn, GJ (2005). Assessing BVD control options by their relative contribution to risk management. Preventive Veterinary Medicine: submitted for publication.Google Scholar
Sørensen, JT, Enevoldsen, C and Houe, H (1995). A stochastic model for simulation of the economic consequences of bovine virus diarrhoea virus infection in a dairy herd. Preventive Veterinary Medicine 23: 215–227.CrossRefGoogle Scholar
Spedding, CRW, Bennet, RM and Done, JT (1987). Control of BVDV: a case for SCBA? In: Harkness, JW (ed). Pestivirus infections of ruminants. A seminar in the CEC Programme of Coordination of Research on Animal Husbandry, 10–11 September 1985, Brussels, pp. 253–273.Google Scholar
Stott, AW, Lloyd, J, Humphry, RW and Gunn, GJ (2003). A linear programming approach to estimate the economic impact of bovine viral diarrhoea (BVD) at the whole-farm level in Scotland. Preventive Veterinary Medicine 59: 51–66.CrossRefGoogle ScholarPubMed
Synge, BA, Clark, AM, Moar, JAE, Nicolson, JT, Nettleton, PF and Herring, JA (1999). [The control of bovine virus diarrhoea virus in Shetland. Veterinary Microbiology] 64: 223–229.CrossRefGoogle ScholarPubMed
Tajima, M, Frey, HR, Yamato, O, Maede, Y, Moennig, V, Scholz, H and Greiser-Wilke, I (2001). Prevalence of genotypes 1 and 2 of bovine viral diarrhea virus in Lower Saxony, Germany. Virus Research 76: 31–42.CrossRefGoogle ScholarPubMed
Thibault, JC, Crevat, D and Chappuis, G (1993). Control of bovine virus diarrhoea—mucosal disease in cattle: examples of the combined use of serological screening, viral antigen detection and vaccination. Revue scientifique et technique 12: 471–481.CrossRefGoogle ScholarPubMed
Valle, PS, Skjerve, E, Martin, SW, Larssen, RB, Øster˚s, O and Nyberg, O (2000). A cost—benefit evaluation of the Norwegian bovine virus diarrhoea control and eradication program. In: Proceedings of the 9th Symposium of the International Society for Veterinary Epidemiology and Economics (ISVEE), 6–11 August 2000, Breckenridge, CO, USA, pp. 1189–1191.Google Scholar
Valle, PS (2004). Ten years of bovine virus diarrhoea virus (BVDV) control—a beneficial joint effort in three parts. In Second European Symposium on BVDV Control, 20–22 October 2004, Porto Portugal, Programme and Abstracts, p. 50.Google Scholar
van Oirschot, JT, Bruschke, CJ van Rijn, PA (1999). Vaccination of cattle against bovine viral diarrhoea. Veterinary Microbiology 64: 169–183.CrossRefGoogle ScholarPubMed
van Regenmortel, MHV, Fauquet, CM, Bishop, DHL, Carstens, EB, Estes, MK, Lemon, SM, Maniloff, J, Mayo, MA, McGeoch, DJ, Pringle, CR and Wickner, RB (2000). Virus taxonomy: the classification and nomenclature of viruses. In: The Seventh Report of the International Committee on Taxonomy of Viruses. Virus Taxonomy, VIIth Report of the ICTV. SanDiego: Academic Press, pp. 867–872.Google Scholar
Vannier, P, Vedeau, F and Allemeersch, C (1997). Eradication and control programmes against Aujeszky's disease (pseudorabies) in France. Veterinary Microbiology 55: 167–173.CrossRefGoogle ScholarPubMed
Voss, H (2004). The BVD situation in Denmark, development and surveillance program. In: Proceedings of the 2nd European Symposium on BVDV Control, 20–22 October 2004, Oporto, Portugal, p. 102.Google Scholar
Wells, SJ, Ott, SL Hillberg Seitzinger (1998). Key health issues for dairy cattle—new and old. Journal of Dairy Science 81: 3029–3035.CrossRefGoogle ScholarPubMed
Willeberg, P (2004). The role of official authorities in animal disease control. In: Second European Symposium on: BVDV Control, 20–22 2004, Porto Portugal, Programme and Abstracts, pp. 51–52.Google Scholar
Yekutiel, P (1980). Eradication of infectious diseases: A critical study. In: Contribution to Epidemiology and Biostatistics, Vol. 2. Basel: Karger, Switzerland, 164 pp.Google Scholar