Published online by Cambridge University Press: 01 August 2014
The injection of human leukemic blood in chicken embryos before incubation determines a characteristic reticuloendotheliosis, which may be transmitted from embryo to embryo and even to the adult fowl. The viral agent responsible for this reticuloendotheliosis is filtrable and inactivated by heat. Intradermal injection of affected-embryo homogenates in leukemic patients determines a local allergic reaction. Electron microscopy has shown the existence of virus-like particles in the cells of inoculated embryos.