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The Use of Sequential Analysis to Improve the Efficiency of Co-twin Control Studies

Published online by Cambridge University Press:  01 August 2014

J. C. Christian ,
P. L. Yu ,
C. E. Grim  and
J. A. Norton Jr.
J. C. Christian*
Affiliation:
Departments of Medical Genetics, Indiana University School of Medicine, Indianapolis
P. L. Yu
Affiliation:
Departments of Medical Genetics, Indiana University School of Medicine, Indianapolis
C. E. Grim
Affiliation:
Departments of Medicine, and, Indiana University School of Medicine, Indianapolis
J. A. Norton Jr.
Affiliation:
Departments of Psychiatry, Indiana University School of Medicine, Indianapolis
*
Department of Medical Genetics, Indiana University School of Medicine, 1100 West Michigan Street, Indianapolis, IN 46202, USA

Abstract

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The co-twin control model using paired-comparison analysis provides an extremely powerful and cost-effective experimental design for clinical research. This paper suggests the possibility of using sequential analysis to further increase the efficiency and specificity of cotwin control studies.

Keywords

Co-twin control studiesSequential analysisExperimental designPaired comparisonsMethodologyEfficiency
Type
Short Note
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 29 , Issue 2 , April 1980 , pp. 163 - 165
Copyright
Copyright © The International Society for Twin Studies 1980

References

REFERENCES

1.Armitage, P (1975): “Sequential Medical Trials.” New York: John Wiley and Sons Inc.Google Scholar
2.Christian, JC, Kang, KW (1972): Efficiency of human monozygotic twins in metabolic studies of blood lipids. Metabolism 21:691–699.Google Scholar
3.Schneiderman, MA, Armitage, P (1962): A family of closed sequential procedures. Biometrika 49:41–56.Google Scholar
4.Schneiderman, MA, Armitage, P (1962): Closed sequential t-tests. Biometrika 49:359–366.Google Scholar
5.Wald, A (1947): “Sequential Analysis.” New York: John Wiley and Sons, Inc.Google Scholar