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Twins in Sibships with Klinefelter's Syndrome and the XYY Syndrome

Published online by Cambridge University Press:  01 August 2014

J. Nielsen
J. Nielsen*
Affiliation:
The Cytogenetic Laboratory, Århus State Hospital, Risskov, Denmark
*
The Cytogenetic Laboratory, Århus State Hospital, Risskov, Denmark

Summary

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The frequency of twins and triplets was significantly higher than expected among 56 patients with Klinefelter's syndrome (7.1%), compared with 1.58% in the population (P<0.001), and the frequency of multiple births in the 56 sibships (4.08%) was also significantly higher than expected (P<0.01).

One of 15 patients with the XYY syndrome was a twin, and there were 2 twin births among the 53 births in the 15 sibships.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 19 , Issue 3 , July 1970 , pp. 399 - 404
Copyright
Copyright © The International Society for Twin Studies 1970

References

Ferguson-Smith, M. A. (1966). Sex chromatin, Klinefelter's syndrome and mental deficiency. In Moore, K. L.: The Sex Chromatin. W. B. Saunders Co., Philadelphia, pp. 277–315.Google Scholar
Nielsen, J. (1966). Twins in sibships with Klinefelter's syndrome. J. Med. Genet., 3: 114–116.CrossRefGoogle ScholarPubMed
Nielsen, J. (1968). Twins and Klinefelter's syndrome. Acta Genet. Med. Gemellol., 17: 385–388.CrossRefGoogle ScholarPubMed
Soltan, H. C. (1968). Genetic characteristics of families of XO and XXY patients, including evidence of source of X chromosomes in 7 aneuploid patients. J. Med. Genet., 5: 173–180.CrossRefGoogle ScholarPubMed