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Twin Zygosity Diagnosis by Mailed Questionnaire below Age Twelve Months

Published online by Cambridge University Press:  01 August 2014

C. Charlemaine ,
M. Duyme ,
J-T. Aubin ,
F. Guis ,
N. Marquiset ,
I. de Pirieux ,
N. Strub ,
Y. Brossard ,
G. Jarry  and
R. Frydman
...Show all authors
C. Charlemaine*
Affiliation:
INSERM - U. 155. Genetic Epidemiology - University of Paris VII, France
M. Duyme
Affiliation:
INSERM - U. 155. Genetic Epidemiology - University of Paris VII, France
J-T. Aubin
Affiliation:
Saint Antoine Hospital; Paris, France
F. Guis
Affiliation:
Antoine Béclère Hospital, Clamart, France
N. Marquiset
Affiliation:
Antoine Béclère Hospital, Clamart, France
I. de Pirieux
Affiliation:
Antoine Béclère Hospital, Clamart, France
N. Strub
Affiliation:
Antoine Béclère Hospital, Clamart, France
Y. Brossard
Affiliation:
Saint Antoine Hospital; Paris, France
G. Jarry
Affiliation:
Antoine Béclère Hospital, Clamart, France
R. Frydman
Affiliation:
Antoine Béclère Hospital, Clamart, France
J. C. Pons
Affiliation:
Gynecology Obstetrics Department, Cochin Port-Royal Hospital, Paris, France
*
INSERM - U. 155. Epidémiologie génétique - Universite Paris VII, Tour 16 - Case 7041 - 2, Place Jussieu - 75251, Paris 05, France ([email protected])

Abstract

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Parents of a sample of 76 same sexed pairs of twins aged 3 to 9 months completed a mailed similarity questionnaire. It included the Bonnelykke et al.'s questionnaire and a four anthropological variable scale. To improve each of these two methods, three other combined methods were carried out and results were compared with the biological zygosity diagnosis. The Bonnelykke et al.'s classification combined with anthropological scale (method 4) gave only 1.2% misclassified in the whole sample. It is concluded that zygosity diagnosis using this type of procedure to distinguish MZ and DZ pairs would be important not only for epidemiological study but also for pediatricians and parents.

Keywords

Zygosity diagnosisQuestionnaireTwins
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 46 , Issue 3 , July 1997 , pp. 147 - 156
Copyright
Copyright © The International Society for Twin Studies 1999

References

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