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Reproduction in a Mongoloid

Published online by Cambridge University Press:  01 August 2014

Karl A. Stiles
Affiliation:
Department of Zoology of Michigan State University, East Lansing Michigan, U. S. A.
Harold O. Goodman
Affiliation:
Department of Medical Genetics, Bowman Gray School of Medicine, Winston-Salem, North Carolina, U. S. A.

Extract

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Reproduction in mongoloids is a rarity. Allen and Baroff (1955) cite only four reports prior to 1949 which described such instances and Øster (1953) considered the diagnoses uncertain in two of those reports. At least seven more recent instances have been recorded (Le Long, Borniche, Kreisler, and Baudy, 1949; Sawyer, 1949; Forsmann and Thysell, 1957; Rehn and Thomas, 1957; Schlaug, 1957; Mullins, Estrada, and Gready, 1960; and Hanhart, 1960). In four of those cases the offspring were non-mongoloid and in three, mongoloid.

The case described by Rehn and Thomas (op. cit.) is the subject of this report. Because those authors were aware of the present comprehensive study, their diagnoses of mongolism were based on only routine clinical examinations. The purpose in making this investigation was to determine whether or not both the mother and her female offspring were mongoloid. Toward that end the mother and child were examined carefully for the presence of the various stigmata of mongolism. The results of those examinations are presented below.

The mother in the present case was living at home when 19 years of age and would probably not have been committed to an institution had she not become pregnant. She was committed with the diagnosis of mongolism and pregnancy three months prior to delivery and remained a patient at the institution until released on home parole a few months following delivery. Her child was committed with a diagnosis of mongolism shortly after birth and has never been away from the institution. Paternity is unknown, though the mother's father has been suspected.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1961

References

Literature

Allen, G. and Baroff, G. S. 1955. Mongoloid twins and their siblings. Acta genet., 5: 294.Google ScholarPubMed
Benda, G. E. 1939. Studies in mongolism: II. The thyroid gland. Arch. Neurol. and Psychiat., 41: 243.CrossRefGoogle Scholar
Block, R. J., Durrum, E. L., and Zweig, G. 1955. Paper Chromatography and Paper Electrophoresis. Academic Press, New York, 484 pp.Google Scholar
Böök, J. A., Fraccaro, M. and Lindsten, J., 1959. Cytogenetical observations in mongolism. Acta Paediat., 48: 453.Google ScholarPubMed
Caffey, J. 1950. Pediatric X-ray Diagnosis. The Year Book Publishers, Chicago Illinois, 862 pp.Google Scholar
Carver, M. J., Wiltse, H. and Wittson, C. L. 1959. Basic studies in mongolism. I. Serum proteins. Dis. Nerv. Sys., 20: 162.Google ScholarPubMed
Cummings, H. 1939. Dermatoglyphic stigmata in mongoloid inbecilcs. Anat. Rec., 73: 407.CrossRefGoogle Scholar
Forsmann, H. and Thysell, T. 1957. A woman with mongolism and her child. Am. J. Ment. Period Defic., 62: 500.Google Scholar
Fraccaro, M., Kaijser, K., and Lindsten, J. 1960. Chromosomal abnormalities in father and mongol child. Lancet, 1: 724.CrossRefGoogle ScholarPubMed
Lang-Brown, H., Lawler, S. D., and Penrose, L. S. 1953. The blood typing of cases of mongolism, their parents and sibs. Ann. Eug., 17:307.CrossRefGoogle ScholarPubMed
Le Long, M., Borniche, P., Kreisler, and Baudy, . 1949. Mongolien essu de mère mongolionne, Arch. franç. pédiat., 6: 231.Google Scholar
de Lorimier, A. A., Moehring, H. G. and Hannan, J. R. 1954. Clinical Roentgenology, Vol. II. Charles C. Thomas Company, Springfield, Illinois, 464 pp.Google Scholar
Lowe, R. F. 1949. The eyes in mongolism. Brit. J. Ophth., 33:131.CrossRefGoogle ScholarPubMed
Mullins, D. H., Estrada, W. R., and Gready, T. G. 1960. Pregnancy in an adult mongoloid female. Obst. and Gynec., 15: 781.Google Scholar
Øster, J. 1953. Mongolism. Op. Dom. Biol. Hum. Univ. Hafn., 32: 1206.Google Scholar
Penrose, L. S. 1934. Mental Defect. Farrar and Rinehart, Inc. New York, 205 pp.Google Scholar
Penrose, L. S. 1954. The distal triradius t on the hands of parents and sibs of mongol imbeciles. Ann. Hum. Gen., 19: 10.CrossRefGoogle ScholarPubMed
Penrose, L. S. 1957. Similarity of blood antigens in mother and mongol child. J. Ment. Def. Res., 1: 107.Google ScholarPubMed
Polani, P. E., Briggs, J. H., Ford, C. E., Clarke, C. M., and Berg, J. M. 1960. A mongol girl with 46 chromosomes. Lancet, 1: 721.CrossRefGoogle ScholarPubMed
Rehn, A. T. and Thomas, E. 1957. Family history of a mongoloid girl who born a mongoloid child. Am. J. Ment. Defic., 62: 496.Google Scholar
Sawyer, G. M. 1949. Case report: Reproduction in a mongoloid. Am. J. Ment. Defic. 54: 204.Google Scholar
Sawyer, G. M., Shafter, A.J. 1957. Reproduction in a mongoloid: A follow-up. Am. J. Ment. Defic., 61: 793.Google Scholar
Schlaug, R. 1957. A mongolian mother and her child. A case report. Acta. Genet., 7: 533.Google ScholarPubMed
Simon, A., Ludwig, C., and Gofman, J. W. 1954. Metabolic studies in mongolism: Serum protein-bound iodine, cholesterol, and lipoprotein.CrossRefGoogle Scholar
Spitzer, R. and Robinson, M. J. 1955. Radiological changes in teeth and skull in mental defectives. Brit. J. Radiol., 28: 117.CrossRefGoogle ScholarPubMed
Spitzer, R. and Robinson, M. J. and Quillam, R. L. 1958. Observations on congenital anomalies in teeth and skull in two groups of mental defectives (a comparative study). Brit. J. Radiol., 31: 596.CrossRefGoogle ScholarPubMed
Stuart, H. C. and Stevenson, S. S. 1950. Textbook of Pediatrics, Nelson, W. E., Ed., W. B. Saunders Co., Philadelphia, 1658 pp.Google Scholar
Walker, N. F. 1957a. Inkless methods of finger, palm, and sole printing. J. Pediat., S. Louis, 50: 27.Google Scholar
Walker, N. F. 1957b. The use of dermal configurations in the diagnosis of mongolism. J. Pediat., S. Louis, 50: 19.Google Scholar