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Relationship Between Blood Uric Acid Level and Personality Traits

Published online by Cambridge University Press:  01 August 2014

S. Ooki ,
K. Yamada  and
A. Asaka
S. Ooki*
Affiliation:
School of Health Sciences, Faculty of Medicine, University of Tokyo, Japan
K. Yamada
Affiliation:
Department of Nursing, Sapporo Medical College, Japan
A. Asaka
Affiliation:
Department of Health Sciences, Yamanashi Medical College, Japan
*
Dept. of Mental Health, Tokyo University, 7-3-1 Hongo Bunkyoku, Tokyo 113, Japan

Abstract

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The present study deals with the relationship between blood uric acid level and human behavior. Subjects were 37 MZ and 7 DZ twins aged from 18 to 45 years. In males, blood uric acid level increased with age, while it decreased with age in females. Blood uric acid level was corrected and standardized using regression lines separately for males and females. The distribution of standardized uric acid level corresponded well with the theoretical curve of normal distribution. The intraclass correlation coefficient for standardized uric acid level was r = 0.370 (P < 0.05) for the 37 MZ twins, but not significant for the 7 DZ twins. These findings suggest that blood uric acid level is genetically controlled. By the analysis of 12 personality traits in YG (Yatabe-Guilford) character test, it was revealed that “General activity” was more controlled by genetically than environmentally. In the evaluation of the correlation between standardized uric acid level and the YG 12 personality traits, significant correlation was observed in “Lack of agreeableness” and “Rhathymia”. Since these two personality traits include the factor of “activity”, it is concluded that the plasma uric acid level and activity in a broader sense are under genetic control. This conclusion is consistent with the generally accepted view that persons with high uric acid level are more active and energetic than those with low level.

Keywords

Uric acidTwinsPersonality traits
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 39 , Issue 1 , January 1990 , pp. 117 - 122
Copyright
Copyright © The International Society for Twin Studies 1990

References

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