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The Possible Role of Homeotic Genes in the Causation of Malformations in Monozygotic Twins

Published online by Cambridge University Press:  01 August 2014

David B. Flannery*
Affiliation:
Department of Pediatrics, Medical College of Georgia, Augusta, USA
*
Division of Medical Genetics, Department of Pediatrics, Medical College of Georgia, Augusta, GA 30912, USA

Abstract

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It is proposed that the malformations observed to occur with increased frequency in monozygotic twins are similar to the types of malformations caused by mutation in homeotic genes in animals.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1987

References

REFERENCES

1.Ambros, V, Horvitz, HR (1984): Heterochronic mutants of the nematode Caenorhabditis elegans. Science 226:409416.Google Scholar
2.Gehring, WJ (1985): The molecular basis of development. Scientific American 253:153162.Google Scholar
3.Nance, WE (1977): The use of twins in clinical research. Birth Defects: Original Article Series 13(6): 19:44.Google Scholar
4.Nusslein-Volhard, C, Wieschaus, E (1980): Mutations affecting segment number and polarity in Drosophila. Nature 287:795801.CrossRefGoogle ScholarPubMed
5.Schinzel, AAGL, Smith, DW, Miller, JR (1979): Monozygotic twinning and structural defects. J Pediatr 95:921930.CrossRefGoogle ScholarPubMed