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Plasma Protein Variability in Monozygotic Twins: Further Studies and Applications

Published online by Cambridge University Press:  01 August 2014

M. Milani-Comparetti ,
F. Britti ,
D. Casini ,
F. Saccucci  and
L. Gedda
M. Milani-Comparetti*
Affiliation:
Institute of Biology and Genetics, University of Ancona, Italy
F. Britti
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Studies, Rome, Italy
D. Casini
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Studies, Rome, Italy
F. Saccucci
Affiliation:
Institute of Biology and Genetics, University of Ancona, Italy
L. Gedda
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Studies, Rome, Italy
*
Istituto di Biologia e Genetica, Via Grotte di Posatora, 60100 Ancona, Italy

Abstract

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Previous collaborative studies have shown the substantial superimposability of electrophoretic patterns of non-Ig plasma proteins in twin pairs only if MZ. The above findings provide the basis for (a) twin pair zygosity determinations and (b) studies aimed at discriminating genetic and environmental factors in the alteration of protein patterns in various diseases (especially neoplastic). Such studies require adequate standardization of methods, and the present paper offers a substantial contribution to the standardization of pattern comparisons.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 26 , Issue 3-4 , October 1977 , pp. 239 - 246
Copyright
Copyright © The International Society for Twin Studies 1977

References

REFERENCES

Gedda, L., Milani-Comparetti, M., D'Alessandro, E. 1974. Equivocalness and other empirical methods in zigosity assessment. 1st Int. Congr. Twin Studies, Rome. Acta Genet. Med. Gemellol., (1976) 25: 117–120.CrossRefGoogle Scholar
Milani-Comparetti, M., Saccucci, F. 1974. Plasma protein variability in MZ twins. 1st. Int. Congr. Twin Studies, Rome. Acta Genet. Med. Gemellol., (1976) 25: 154–156.CrossRefGoogle Scholar
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