Hostname: page-component-7bb8b95d7b-cx56b Total loading time: 0 Render date: 2024-09-13T11:40:28.966Z Has data issue: false hasContentIssue false
  • English
  • Français

Our experience with 5-Fluoro-2-Desoxyuridine

Published online by Cambridge University Press:  01 August 2014

G. Brulé  and
S. Hane
G. Brulé
Affiliation:
Institut Gustave Roussy, Villejuif/Seine
S. Hane
Affiliation:
Institut Gustave Roussy, Villejuif/Seine

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The authors report 13 observations concerning solid tumors treated with 5-fluoro-2-deoxyuridine.

11 of the patients have received protracted infusions at the rate of 1 mg/kg/24h during about a week.

2 patients have received the drug by direct intravenous injection at the rate of 15 mg/kg/24h during 6 days for one of them and during 12 days for the other one. These two methods are discussed according to the results and toxicity of both of them.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 17 , Issue 1 , January 1968 , pp. 153 - 157
Copyright
Copyright © The International Society for Twin Studies 1968

References

Bibliographie

Helderberger, C., Ansfield, F. J. (1963). Experimental and clinical use of florinated pyrimidines in cancer chemotherapy. Cancer Res., 23: 1226–1243.Google Scholar
Muckherjee, K. L. et al. (1963). Studies on fluorinated pyrimidines. DVI - Metabolism of 5-fluorouracil-2-C14 and 5-fluoro-2-deoxyuridine-2-C14 in cancer patients. Cancer Res., 23: 49–66.Google Scholar
Muckherjee, K. L. et. al. (1963). Studies on fluorinated pyrimidines. XVII - Tissue distribution of 5-fluorouracil-2-C14 and 5-fluoro-2-deoxyridine-2-C14 in cancer patients. Cancer Res., 23: 67–77.Google Scholar
Murphy, M. L. et al. (1959). Preliminary clinical studies with 5-FRDR in acute leukemia. Cancer Chemother. Rep., 2: 12–13.Google Scholar
Muckherjee, K. L. (1959). Clinical toxicity and preliminary trials of 5-FUDR in acute leukemia. Proc. Amer. Ass. Cancer Res., 3: 46.Google Scholar
Sullivan, R. D. et al. (1964). Chemotherapy of metastatic liver cancer by prolonged hepatic artery infusion New Eng. J. Med., 270: 321–327.Google Scholar
Watkins, E. (1963). Chronometric infusor - an apparatus for protracted ambulatory infusion therapy. New Eng. J. Med., 269: 850–851.Google Scholar