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Neurotransmitters and Neuromodulators

Published online by Cambridge University Press:  01 August 2014

Felix A. Steiner
Felix A. Steiner*
Affiliation:
Department of Experimental Medicine, F. Hoffmann-La Roche Co. Ltd., Basel, and Institute for Brain Research, University of Zurich, Switzerland
*
c/o F. Hoffmann-La Roche & Co. Ltd, Grenzacherstrasse 124, 4002 Basel, Switzerland

Abstract

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In the central nervous system, besides the neurotransmitters, the occurrence of substances which modify neuronal excitability has been proposed. Since their effect is a matter of modulating neuronal responsiveness, these substances may be called neuromodulators.

Examples of neurotransmitters or putative neurotransmitters in the central nervous system are acetylcholine, noradrenaline, dopamine, and aminoacids such as GABA, glycine, and L-glutamic acid. Under certain conditions, some of these (acetylcholine, L-glutamic acid, and GABA), as well as hormones and polypeptides (e.g., releasing factors) are considered to act as neuromodulators.

Type
3. Genetics of Disorders of Nerves and Synapses
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 23 , supplement S1 , January 1974 , pp. 123 - 128
Copyright
Copyright © The International Society for Twin Studies 1974

References

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