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Muscular Dystrophy in Three Pairs of Twins1

Published online by Cambridge University Press:  01 August 2014

Hubert C. Soltan
Hubert C. Soltan*
Affiliation:
Department of Genetics, Research Institute, Hospital for Sick Children, Toronto, Canada

Summary

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Three pairs of male twins concordant for muscular dystrophy are presented. Two of these pairs are shown to be monozygotic and affected with the Duchenne form of muscular dystrophy. The third pair is probably dizygotic. The clinical and genetical features of each pair of twins are discussed. Pedigrees with photographs of the twins are presented.

Riassunto

RIASSUNTO

Sono stati presentati tre paia di gemelli di sesso maschile con lo stesso tipo di distrofia muscolare. Due paia sono monozigoti ed affetti con una forma di distrofia muscolare Duchenne. Il terzo paio è probabilmente dizigoto. I caratteri clinici e genetici di ogni paio di gemelli sono discussi. Pedigrees con fotografie dei gemelli sono presentati.

Zusammenfassung

ZUSAMMENFASSUNG

Drei fälle von männlichen Zwillingen, übereinstimmend an Muskelschwund erkrankt, sind hier aufgeführt. Zwei von den genannten Fällen werden als eineiige Zwillinge und mit der Duchenne Form von Muskeldystrophie gezeigt. Das dritte Zwillingspaar ist wahrscheinlich zweieiig. Die klinischen und genetischen Charakeristiken jedes Zwillingpaares sind besprochen, und Ahnentafeln und Photographien der Zwillinge sind aufgeführt.

Résumé

RÉSUMÉ

Trois paires des jumeaux masculines concordant sont présentés. Deux paires de ces jumeaux sont démontrés comme MZ et tarés par la forme Duchenne. La troisième paire est probablement DZ. Les traits cliniques et génétiques de chaque paire des jumeaux sont discutés. Les arbres généologiques des jumeaux ainsi que des photographies sont présentés.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 8 , Issue 4 , October 1959 , pp. 434 - 442
Copyright
Copyright © The International Society for Twin Studies 1959

Footnotes

1

This work was supported by a grant from the Muscular Dystrophy Association of Canada.

References

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