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Morbo di Addison familiare (Iposurrenalismo cronico « parzialmente compensato » insorto in padre e figlio dopo l'influenza asiatica)1

Published online by Cambridge University Press:  01 August 2014

R. Toccafondi  and
A. Borghi
R. Toccafondi
Affiliation:
Istituto di Patologia Speciale Medica e Metodologia Clinica dell'Università di Firenze
A. Borghi
Affiliation:
Istituto di Patologia Speciale Medica e Metodologia Clinica dell'Università di Firenze

Summary

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Two familial cases (father and son) of Addison disease, occurred after « asian influenza », are reported.

Clinical data suggest tat the pathological basis for adrenal insufficiency could be the so-called « simple fibrosclerosis » and that virus infection has acted as a precipitating factor of an underlying adrenal meyopragy, since both patients as well as other members of the same familyi have a hyperpigmentated skin.

The two patients have shown a Addison syndrome « partially compensate » with incomplete symptomatology for lack of functional adrenal reserve which has been detected only by ACTH stimulation (which was inefficient).

As far as we know, this is the first report of a chronic hypercorticalism occurred in the father and one of his sons.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 11 , Issue 4 , October 1962 , pp. 407 - 417
Copyright
Copyright © The International Society for Twin Studies 1962

Footnotes

1

Il lavoro spetta in parti uguali ai due autori. II Direttore.

References

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