Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-23T05:48:06.207Z Has data issue: false hasContentIssue false

Intrapair Similarity of Immunoglobulin Levels in Twins

Published online by Cambridge University Press:  01 August 2014

K. Kouvalainen*
Affiliation:
Department of Paediatrics, University of Oulu, Finland
I. Moilanen
Affiliation:
Department of Paediatrics, University of Oulu, Finland
*
Department of Pediatrics, University of Oulu, SF-90220 Oulu, Finland

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Levels of immunoglobulins IgG, IgA, IgM and IgE were determined in 8 MZ and 14 DZ twin pairs at the ages of 6-11 years, 12-17 years and 15-20 years. Intrapair similarity in immunoglobulin levels was found to be higher in the MZ than in the DZ twins, especially in the case of immunoglobulins IgA and IgM.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1987

References

REFERENCES

1. Dorf, M (1981): The Role of the Major Histocompatibility Complex in Immunobiology. New York: Garland STPM Press.Google Scholar
2. Hamburger, RN (1982): The immunogenetics of IgE provides predictive value for the development of allergy. Ann Allergy 49:911.Google ScholarPubMed
3. Jormalainen, S, Mozes, E, Sela, M (1975): Genetic control of the immune response. The dose of antigen in aqueous solution is criticai in determining which mouse strain is high responder to poly (LTyr, LGlu)-poly(LPro) - - poly(LLys). J Exp Med 141:1057–72.CrossRefGoogle Scholar
4. Kjellman, N-JM (1976): Predictive value of high IgE levels in children. Acta Paediatr Scand 65: 465–71.CrossRefGoogle ScholarPubMed
5. Mancini, G, Carbonara, AO, Heremans, JF (1965): Immunochemical quontitation of antigens by single radial diffusion. Int J Immunochem 2:235–54.CrossRefGoogle Scholar
6. Newman, HH, Freeman, FN, Holzinger, KJ (1973): Twins: A study of Heredity and Environment. Chicago: University of Chicago Press.Google Scholar
7. Sarna, S (1977): Zygosity Diagnosis in Epidemiological Twin Studies. Publications from the University Departments of Public Health in Finland M23.Google Scholar
8. Sasazuki, T, Nishimura, Y, Muto, M (1984): MHC-linked immune suppression genes and their role in immunological disorders. In Sasazuki, T, Tada, T (eds): Immunogenetics. Its Application to Clinical Medicine Tokyo: Academic Press, pp 2137.Google Scholar
9. Schwartz, RH (1984): The role of gene products in the major histocompatibility complex in T cell activation and cellular interactions. In Paul, WE (ed): Fundamental Immunology, Chapter 15. New York: Raven Press.Google Scholar
10. Sistonen, P, Johnsson, V, Koskenvuo, M, Aho, K (1980): Serum IgE levels in twins. Hum Hered 30:155158.CrossRefGoogle ScholarPubMed
11. Tourain, J-L, Beruel, H, Touraine, F (1984): The bare lymphocyte syndrome. In Griscelli, C, Vossen, J (eds): Progress in Immunodeficiency Research and Therapy. Amsterdam: Elsevier.Google Scholar
12. Wigzell, H (1973): Is it all coded for by the germ line genes? Scand J Immunol 2:199206.CrossRefGoogle ScholarPubMed