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Heritability of Systolic Blood Pressure. Analysis of Variance in MZ Twin Parents and Their Children

Published online by Cambridge University Press:  01 August 2014

R. J. Rose ,
D. W. Fulker ,
J. Z. Miller ,
C. E. Grim  and
J. C. Christian
R. J. Rose*
Affiliation:
Department of Psychology, Indiana University, Bloomington
D. W. Fulker*
Affiliation:
Institute of Psychiatry, University of London
J. Z. Miller
Affiliation:
Department of Psychology, Indiana University, Bloomington
C. E. Grim
Affiliation:
Department of Medicine
J. C. Christian
Affiliation:
Department of Medical Genetics, Indiana University School of Medicine, Indianapolis
*
Department of Psychology, Indiana University, Bloomington IN 47405
Institute of Psychiatry, Bethlem Royal Hospital, Beckenham BR 3 3BX, UK

Abstract

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Systolic blood pressure, standardized for age and sex, was measured in 76 MZ twin pairs and their 341 children. Maximum likelihood estimation of genetical and environmental parameters from the independent parental and offspring ANOVAs indicated a complete absence of both maternal and shared environmental effects, together with a heritability of 63%. These results are shown to be reasonably consistent with those from previous studies.

Keywords

Systolic blood pressureMaximum likelihood genetic analysisTwin model
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 29 , Issue 2 , April 1980 , pp. 143 - 149
Copyright
Copyright © The International Society for Twin Studies 1980

References

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