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HCS, HCG, and HCG Subunit Serum Levels During Multiple Pregnancies

Published online by Cambridge University Press:  01 August 2014

U. Gaspard*
Affiliation:
Department of Obstetrics and Gynecology, and Laboratory of Radioimmunology, Institute of Medicine, University of Liège, Belgium
P. Franchimont
Affiliation:
Department of Obstetrics and Gynecology, and Laboratory of Radioimmunology, Institute of Medicine, University of Liège, Belgium
*
Service de Gynécologie et d'Obstétrique, Université de Liège, Boulevard de la Constitution 81, 4000 Liège, Belgium

Abstract

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HCS, HCG, and HCG α and β subunits were measured in the serum of women with unifetal or multiple pregnancies. Highly specific radioimmunoassay procedures were used for the determinations.

Serum maternal levels of HCS are greatly increased in multiple pregnancies, sometimes more than could be expected from increased placental weight alone. Serum undissociated HCG is also elevated in multiple pregnancies. The relationship between undissociated HCG and its free circulating α and β subunits is different in multiple and unifetal pregnancies and this difference is discussed.

Type
5. The Twinning Phenomenon: Etiologic, Genetic, and Demographic Aspects
Copyright
Copyright © The International Society for Twin Studies 1972