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Gestational Age-Specific Birthweights of Twins Versus Singletons

Published online by Cambridge University Press:  01 August 2014

B. Luke ,
F.R. Witter ,
H. Abbey ,
T. Feng ,
A.B. Namnoum ,
D.M. Paige  and
T.R.B. Johnson
B. Luke*
Affiliation:
Division of Maternal-Fetal Medicine, School of Medicine, Department of Maternal and Child Health, and Department of Biostatistics, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
F.R. Witter
Affiliation:
Division of Maternal-Fetal Medicine, School of Medicine, Department of Maternal and Child Health, and Department of Biostatistics, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
H. Abbey
Affiliation:
Division of Maternal-Fetal Medicine, School of Medicine, Department of Maternal and Child Health, and Department of Biostatistics, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
T. Feng
Affiliation:
Division of Maternal-Fetal Medicine, School of Medicine, Department of Maternal and Child Health, and Department of Biostatistics, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
A.B. Namnoum
Affiliation:
Division of Maternal-Fetal Medicine, School of Medicine, Department of Maternal and Child Health, and Department of Biostatistics, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
D.M. Paige
Affiliation:
Division of Maternal-Fetal Medicine, School of Medicine, Department of Maternal and Child Health, and Department of Biostatistics, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
T.R.B. Johnson
Affiliation:
Division of Maternal-Fetal Medicine, School of Medicine, Department of Maternal and Child Health, and Department of Biostatistics, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
*
Dept. Gyn/Ob, Houck 228, The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21205, USA

Abstract

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In order to more adequately characterize patterns of intrauterine growth retardation in twins, the mean birthweights of all nonanomalous white or black twins born between 24 and 41 weeks of gestation and surviving until discharge over an 11-year period (547 infants) and all similar singletons (19,072 infants) were compared by completed weeks of gestation. Between 24 and 35 weeks of gestation, the mean birthweights for the 547 twins and the 19,072 singletons were comparable and did not consistently differ statistically. From 36 to 41 weeks gestation, however, the difference became large, consistent, and statistically significant for each week at P < 0.0001. This difference was present among all subgroups of twins, ie, in all males, females, blacks, and whites; it was still evident when the sample was further stratified by both race and sex (black males, white males, black females, white females). These data suggest a pattern of growth retardation in twins compared to singletons which is large, consistent, and statistically significant beginning at 36 weeks gestation. Clinically, these data also suggest the need for ultrasonic examination early in gestation (24-32 weeks) to document normal growth and to provide baseline data, and show the importance of such monitoring later in gestation, specifically after 36 weeks.

Keywords

TwinsBirthweightGrowth-retardationRace
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 40 , Issue 1 , January 1991 , pp. 69 - 76
Copyright
Copyright © The International Society for Twin Studies 1991

References

REFERENCES

1.Bleker, OP, Breur, W, Huidekoper, BL (1979): A study of birth weight, placental weight and mortality of twins as compared to singletons. Brit J Obstet Gynaecol 86:111–118.Google Scholar
2.Botting, BJ, MacDonald Davies, I, MacFarlane, AJ (1987): Recent trends in the incidence of multiple births and associated mortality. Arch Dis Child 62:941–950.CrossRefGoogle ScholarPubMed
3.Bronsteen, R, Goyert, G, Bottoms, S. (1989): Classification of twins and neonatal morbidity. Obstet Gynecol 74:98–101.Google Scholar
4.Fabre, E, Gonzalez de Aguero, R, de Agustin, JL, Perez-Hiraldo, MP, Bescos, JL (1988): Perinatal mortality in twin pregnancy: An analysis of birth weight-specific mortality rates and adjusted mortality rates for birth weight distributions. J Perinat Med 16:85–91.CrossRefGoogle ScholarPubMed
5.Ferrazzi, E, Nicolini, U, Kustermann, A, Pardi, G (1986): Routine obstetric ultrasound: Effectiveness of cross-sectional screening for fetal growth retardation. J Clin Ultrasound 14:17–22.CrossRefGoogle ScholarPubMed
6.Gruenwald, P (1970): Environmental influences on twins apparent at birth. Biol Neonate 15:79–93.Google Scholar
7.Guaschino, S, Spinillo, A, Stola, E, Pesando, PC (1987): Growth retardation, size at birth and perinatal mortality in twin pregnancy. Int J Gynaecol Obstet 25:399–403.CrossRefGoogle ScholarPubMed
8.Leroy, B, Lefort, F, Neveu, P, Risse, RJ, Trevise, P, Jeny, R (1982): Intrauterine growth charts for twin fetuses. Acta Genet Med Gemellol 31:199–206.Google Scholar
9.McKeown, T, Record, RG (1952): Observations on foetal growth in multiple pregnancy in man. J Endocrinol 8:386–401.CrossRefGoogle ScholarPubMed
10.Medearis, AL, Jonas, HS, Stockbauer, JW, Domke, HR (1979): Perinatal deaths in twin pregnancy: A five-year analysis of statewide statistics in Missouri. Am J Obstet Gynecol 134:413–421.Google Scholar
11.Naeye, RL, Benirschke, K, Hagstrom, JWC, Marcus, CC (1966): Intrauterine growth of twins as estimated from liveborn birth-weight data. Ped 37:35–39.Google ScholarPubMed
12.Neilson, JP (1988): Fetal growth in twin pregnancies. Acta Genet Med Gemellol 37:409–416.Google ScholarPubMed
13.Neilson, JP, Whitfield, CR, Aitchison, TC (1980): Screening for the small-for-dates fetus: A two-stage ultrasonic examination schedule. Brit Med J 1:1203–1206.Google Scholar
14.O'Shea, RT (1986): Twin pregnancy: Prematurity and perinatal mortality. Aust NZ J Obstet Gynaecol 26:165–167.CrossRefGoogle ScholarPubMed
15.Schneider, L, Bessis, R, Tabaste, J-L, et al (1978): Echographic survey of twin fetal growth: A plea for specific charts for twins. In Nance, WE, Allen, G, Parisi, P, eds. Twin Research: Clinical Studies. New York: Alan R Liss.Google Scholar
16.Taffel, S (1980): Factors associated with low birth weight, United States, 1976. Vital and Health Statistics, Series 21, No. 37. DHHS Pub. No. (PHS) 80-1915. Hyattsville, Maryland: US Govt Printing Office.Google ScholarPubMed
17.Williams, RL, Creasy, RK, Cunningham, GC, Hawes, WE, Norris, FD, Tashiro, M (1982): Fetal growth and perinatal viability in California. Obstet Gynecol 59:624–632.Google Scholar