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The Ergon/Chronon System in Schizophrenia A Twin Study

Published online by Cambridge University Press:  01 August 2014

L. Braconi
L. Braconi*
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Studies, Rome
*
Istituto di Genetica Medica e Gemellologia Gregorio Mendel, Piazza Galeno 5, 00161 Roma, Italy

Summary

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Ten (eight MM and two FF) MZ twin pairs, with one or both schizophrenic members, have been examined. The disease was concordant in four pairs, discordant in one pair, and partly concordant in five pairs.

The time of onset was simultaneous in five pairs, but showed differences of three years in two pairs, and of one-two years in two more pairs. Concordance in the time of onset was not related to severity of the disease.

Riassunto

Riassunto

Sono state esaminate dieci coppie di gemelli MZ, di cui otto MM e due FF, con almeno un cogemello affetto da schizofrenia. La malattia è risultata concordante in quattro coppie, discordante in una e parzialmente concordante nelle altre cinque.

Il tempo d'insorgenza della malattia è risultato lo stesso in cinque coppie, mentre ha presentato una differenza di tre anni in due coppie e di uno-due anni in altre due. La concordanza nel tempo d'insorgenza non è apparsa in relazione alla gravità della forma.

Résumé

RÉSUMÉ

Dix couples de jumeaux MZ (huit MM et deux FF), avec au moins un membre atteint de schizophrénie, ont été examinés. La maladie s'est démontrée concordante chez quatre couples, discordante chez une, et partiellement concordante chez les autres cinq.

Le temps de début de la maladie a été le même chez cinq couples, mais a différé de trois ans chez deux couples et de un-deux ans chez deux autres. La concordance dans le temps de début n'est pas en rapport à la gravité de la forme.

Zusammenfassung

Zusammenfassung

Es wurden zehn EZ-Paare (acht ♂ u. zwei ♀) untersucht, bei denen wenigstens ein Paarling an Schizophrenie litt. Das Leiden erwies sich bei acht Paaren konkordant, bei einem Paar diskordant und bei den übrigen fünf Paaren teilweise konkordant.

Bei fünf Paaren war die Krankheit gleichzeitig aufgetreten; bei zwei Paaren betrug der Unterschied drei Jahre und bei den anderen beiden Paaren ein bis zwei Jahre. Es zeigte sich kein Zusammenhang zwischen der Konkordanz der Auftrittszeit und der Schwere des Leidens.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 20 , Issue 4 , October 1971 , pp. 373 - 379
Copyright
Copyright © The International Society for Twin Studies 1971

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