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The different interpretations of the mechanism of action of antimitotics and the actual treatment of malignant hemopathies

Published online by Cambridge University Press:  01 August 2014

A. Baserga*
Affiliation:
Istituto di Clinica Medica dell'Università di Ferrara

Summary

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Antimitotic drugs essentially induce a direct inhibition on the malignant cellular proliferation. Secondary mechanisms should even be considered: i.e. neoplastic clonal disadvantage, indirect antivitaminic mechanism for the intestinal atrophy caused by antimitotic drugs, endocrine failance due to the antimitotic drugs damages in the endocrine glands (pharmacological « hypophysectomy » and « castraction ») etc.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1968

References

Bibliographie

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Baserga, A., Castoldi, G. I. (1963). Antineoplastische Chemotherapie und endokrine Drüsen. III Internat. Congr. Chemother., Stuttgart Thieme, 1078.Google Scholar