Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-20T07:21:48.924Z Has data issue: false hasContentIssue false

The Determination of Twin Zygosity by Means of a Mailed Questionnaire

Published online by Cambridge University Press:  01 August 2014

Svenn Torgersen*
Affiliation:
The Norwegian Research Council for Science and the Humanities, Center for Research in Clinical Psychology, University of Oslo
*
Center for Research in Clinical Psychology, PO Box 1039, Blindern, Oslo 3, Norway

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A mailed questionnaire dealing with similarity in childhood, and how often and by whom the twins were mixed up, was applied to 290 same-sex adult twin pairs. For about 75% of pairs ten genetic markers were analysed. The agreement in zygosity classification between questionnaire and blood typing was high. Irrespective of whether raw scores or discriminant function analysis was applied, the agreement was nearly 95%. When a decision tree was applied, the percentage rose to nearly 96%. Considering that probably four of the twin pairs were wrongly classified as MZ by genetic markers, the percentage rose to 96 and 98, respectively.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1979

References

REFERENCES

1.Berg, K (1973): Studies of polymorphic traits for the characterization of populations. The population of Scandinavia. Israel J Med Sci 9:11471155.Google Scholar
2.Cederlöf, R, Friberg, L, Jonsson, E, Kaij, L (1961): Studies on similarity diagnosis in twins with the aid of mailed questionnaires. Acta Genet (Basel) 11:338362.Google ScholarPubMed
3.Cohen, DJ, Dibble, E, Grawe, JM (1973): Separating identical from fraternal twins. Arch Gen Psychiatry 29:465469.Google Scholar
4.Essen-Møller, E (1941): Empirische Ähnlichkeitsdiagnose bei Zwillingen. Hereditas 27:150.CrossRefGoogle Scholar
5.Hauge, M, Harwald, B, Fisher, M, Gotlieb-Jensen, K, Juel-Nielsen, N, Raebild, J, Shapiro, R, Videbech, T (1968): The Danish twin register. Acta Genet Med Gemellol 17:315331.CrossRefGoogle ScholarPubMed
6.Hummel, K, Baumgarten, R (1970): Plausibilitaet der Monozygotic bei gleischgeschlechtlichen Zwillingen auf Grunde blutgruppen-serologischer Befunde. Humangentik 9:286293.Google Scholar
7.Kringlen, E (1967): Heredity and Environment in the Functional Psychoses. Oslo: Universitetsforlaget.Google Scholar
8.Nichols, RC, Bilbro, WC Jr (1966): The diagnosis of twin zygosity. Acta Genet 16:265275.Google Scholar
9.Nie, NH, Hull, CH, Jenkins, JG, Steinbrenner, K, Bent, DH (1975): “Statistical Package for the Social Sciences.” New York: McGraw-Hill, Inc.Google Scholar
10.Sarna, S, Kaprio, J, Sistonen, P, Kosenvuo, M (1978): Diagnosis of twin zygosity by mailed questionnaire. Hum Hered 28:241254.Google Scholar
11.Smith, SM, Penrose, LS (1955): Monozygotic and dizygotic twin diagnosis. Ann Hum Genet 19: 273289.CrossRefGoogle ScholarPubMed
12.Sutton, HE, Clark, PJ, Schull, WJ (1955): The use of multiallele genetic characters in the diagnosis of twin zygosity. J Hum Genet 7:180188.Google ScholarPubMed
13.Torgerson, S (1980): Genetics of neurosis (in preparation).Google Scholar