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Cytogenetische Untersuchungen zur Frage Jahreszeitlicher Schwankung der Spontanen Chromosomenaberrationsrate Beim Menschen

Published online by Cambridge University Press:  01 August 2014

B.R. Deininger  and
H.-D. Rott
B.R. Deininger*
Affiliation:
Institut für Humangenetik und, Anthropologie der Universität Erlangen-Nürnberg
H.-D. Rott
Affiliation:
Institut für Humangenetik und, Anthropologie der Universität Erlangen-Nürnberg
*
Institut für Humangenetik und, Anthropologie der Universität, Bismarckstrasse 10, D-8520 Erlangen, German Federal Republic

Summary

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Monthly chromosomal analyses have been carried out, from December 1971 to November 1972, on 4 male subjects aged 22 to 32. Over a total of 4 710 mitoses examined, the rate of aberrant cells (including gaps) was of 9.1% and there was no difference among individual yearly mean values. The average mitotic index, evaluated on 48 cultures, was of approximately 55‰. Significant differences (P < 0.025) have been found among individual yearly mean values (40-69‰). No seasonal increase of aberrations has been found; however, 12 of the 16 tetraploid cells were found in the winter months. In all subjects, the mitotic index reached its maximum in April-June (P < 0.001). The mitotic index and the percentage of aberrant cells were not shown to be correlated.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 22 , Issue 1 , January 1973 , pp. 19 - 26
Copyright
Copyright © The International Society for Twin Studies 1973

References

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