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Contributo clinico allo studio del mongolismo nei gemelli: presentazione di una coppia di gemelle monozigotiche

Published online by Cambridge University Press:  02 February 2016

M. Alda Bencini
M. Alda Bencini*
Affiliation:
Cattedra delle Malattie Infettive dell’Università di Milano(Italia)

Abstract

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The typical picture of mongolism has been observed in both members of a proved monozygotic twin-pair, aged 15. There is no indication in the family history of any hereditary predisposition, and both, the pregnancy and the birth were quite normal. The author reviews all cases previously reported, and expresses the opinion that mongolism is due to some phenomenon occurring during the germinating period, that is to say during the initial stages of development of the egg.

Riassunto

Riassunto

Elena e Fiorella, gemelle sicuramente MZ di anni 15, presentano il quadro tipico e concordante del mongolismo. L’anamnesi famigliare è negativa anche per tare di altro generela gravidanza ed il parto non presentarono anomalie. L’A. ricorda la casistica precedente ed esprime l’opinione che il mongolismo sia dovuto ad un fenomeno agente nella fase germinativa, e cioè nei primi periodi di formazione dell’uovo.

Résumé

Résumé

Elena et Fiorella, jumelles sûrement MZ Agées de 15 ans, présentent l’image typique et concordante du mongolisme. L’anamnèse familiale est négative et pareillement il n’y a aucune indication de quelque prédisposition héréditaire. La grossesse et l’accouchement ont eu lieu normalement. L’auteur discute l’ensemble des cas précédents, et exprime l’opinion que le mongolisme est dû à un phénomène agissant pendant la phase germinative, c’est-à-dire au cours des premières périodes de la formation de l’œuf.

Zusammenfassung

Zusammenfassung

Die 15 jährigen EZ, Elena und Fiorella, zeigen das konkordante, typiche Krankheitsbild des Mongolismus. Die Familiengeschichte ist negativ und weist keinerlei andere erbliche Belastung auf. Schwangerschaft und Geburt verliefen ebenfalls normal. Die Autorin erinnert an die bestehende Kasuistik und äussert die Meinung, dass der Mongolismus auf einen wahrend der Keimzeit, oder besser während der ersten Fortentwicklung des Eies wirkenden Einfluss zurückzuführen sei.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 1 , Issue 1 , January 1952 , pp. 29 - 39
Copyright
Copyright © The International Society for Twin Studies 1952

References

Bibliografia

Anden, , Brit. M. J., 2, 869, 1947.Google Scholar
Armstrong, , Brit. M. J., 1, 1106, 1928.CrossRefGoogle Scholar
Bauer, , Arch. f. Kinderh., 90, 169, 1930.Google Scholar
Beidleman, , Am. J. Ment. Deficiency, 50, 35, 1945.Google Scholar
Benda, , Mongolism et Cretinism., New York, 1946.Google Scholar
Blechmann, , Karmann, Guillaumin E, Bull. Soc. de Pédiat. de Paris, 30, 387, 1932.Google Scholar
Bleyer, , Am. J. Dis. Child., 55, 79, 1938.CrossRefGoogle Scholar
Brousseau, , Mongolism, Baltimora, 1928.Google Scholar
Brueckner, , Deutsche Med. Wchnschr., 52, 1279, 1926.Google Scholar
Conte, , Christie, Mc Cammon E, Am. J. Dis. Child., 70, 301, 1945 (cit. da Ingalls).Google Scholar
Cozzolino, , Il Lattante, 6, 9, 1935.Google Scholar
Bruin, De, Nederl. tijdschr. v. geneesh., 1, 712, 1902 (cit. da Krabbe).Google Scholar
Dickey, , California & West Med., 26, 344, 1927 (cit. da Warner).Google Scholar
Portius, Doxiades E, Ztschr. f. mesch. Vereb. u. Konstitutionslehre, 21, 384, 1938 (cit. da South wick).Google Scholar
Engler, , Mongolism., Bristol, 1949.Google Scholar
Frumkin, Ford E, Am. J. Dis. Child, 63, 847, 1942 (cit. da Gedda).Google Scholar
Franzi, , L’eredità nella patologia e sulla clinica, Bologna, 1942.Google Scholar
Mitchell, Frazer E, J. Ment. Sci., 22, 169, 1876, (cit. da Warner).Google Scholar
Gedda, , Studio dei gemelli. Roma, 1951.Google Scholar
Geyer, , Zur Aetiologie der Mongoloiden Idiotie, Leipzig, 1939 (cit. da Rondoni).CrossRefGoogle Scholar
Roberts, Gordon E, Arch. Dis. Childhood, 13, 79, 1938 (cit. da Gedda).Google Scholar
Halbertsma, , Am. J. Dis. Child., 25, 350, 1923.Google Scholar
Hjorth, , Nyt Tidsskr. f. Abïiormvaesenet, 9, 17, 1906 (cit. da Krabbe).Google Scholar
Hofmeier, , (cit. da Franzi).Google Scholar
Ingalls, , Am. J. Dis. Child., 74, 147, 1947.Google Scholar
Davies, Ingalls E, Am. J. Dis. Child., 73, 279, 1947 (cit. da Ingalls).Google Scholar
Jenkins, , Am. J. Dis. Child., 45, 506, 1933.Google Scholar
Jervis, , Am. J. Ment. Deficiency, 47, 364, 1943 (cit. da Warner).Google Scholar
Krabbe, , Acta Psychiat. et Neurol., 1, 337, 1926.Google Scholar
Lapage, , Proc. Boy. Soc. Med., 27, 115, 1933.Google Scholar
Lenz, , cit. da Franzi.Google Scholar
Levi, , Biv. di Clinica Pediat., Aprile 1951.Google Scholar
Lund, , Am. J. Dis. Child., 46, 811, 1933.Google Scholar
Mckaye, , Am. J. Dis. Child., 52, 141, 1936.Google Scholar
Mattioli-Foggia, , Gior. di psichiat. e, neuropat., 64, 198, 1936.Google Scholar
Mayerhofer, , Ann. Paediat., 154, 57, 1939.Google Scholar
Mc Lean, , J. A. M. A., 78, 13, 1922.Google Scholar
Downing, Mitchell E, Am. J. M. Sc. 172, 866, 1926, (cit. da Krabbe).Google Scholar
Moretti, , Biv. di Patol. nervosa e mentale, 12, 1913, 1914.Google Scholar
Neumann, , Beri. Klin. Wschr., 10, 210, 1899, (cit. da Halbertsma).Google Scholar
Newman, , Am. J. Phys. Anthropol., 14, 331, 1930 (cit. da Lund).Google Scholar
Orel, , Ztschr. f. Kinderh., 42, 440, 1926.Google Scholar
Penrose, , J. Genetics, 25, 407, 1932.Google Scholar
Pfaunder, , cit. da Franzi. Klein, Eeuben E, Arch. Pediat., 43, 552, 1926.Google Scholar
Rondoni, , Malattie ereditarie.Google Scholar
Handy, Rosanoff E, Am. J. Dis. Child., 48, 764, 1934.Google Scholar
Russel, , Lancet, 1, 802, 1933.Google Scholar
Schachter, , Bev. Franc, de pédiat., 12, 551, 1936.Google Scholar
Shuttleworth, , Brit. M. J., 2, 661, 1909.Google Scholar
Southwick, , Ain. J. Dis. Child., 57, 68, 1939.Google Scholar
Stransky, , Monatsschr. f. Kinderh., 48, 406, 1930 (cit. da Rosanoff).Google Scholar
Strauch, , J. A. M. A., 81, 2181, 1923.Google Scholar
Strukovscaja, , cit. da Schachter e da Franzi.Google Scholar
Stoelzner, , cit. da Franzi.Google Scholar
Stocks, , Ann. Eugenics, 4, 49, 1930 (cit. da Lund).Google Scholar
Tatafiore, , Pediatria, 45, 238, 1937.Google Scholar
Tobler, , Monatsschr. f. Kinderh., 76, 62, 1938.Google Scholar
Turpin, , Rogier, Caratzali E, cit. da Gedda.Google Scholar
Waring, , Am. J. Dis. Child., 41, 351, 1931.Google Scholar
Warner, , Am. J. Dis. Child., 78, 573, 1949.Google Scholar