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Considerazioni e Ricerche genetistiche sul Problema degli omoinnesti*

Published online by Cambridge University Press:  01 August 2014

Luigi Gedda ,
Ezio Gentileschi  and
Giorgio Gentileschi
Luigi Gedda
Affiliation:
Istituto di Genetica Medica e Gemellologia «G. Mendel», Roma (Italia)
Ezio Gentileschi
Affiliation:
Istituto di Genetica Medica e Gemellologia «G. Mendel», Roma (Italia)
Giorgio Gentileschi
Affiliation:
Istituto di Genetica Medica e Gemellologia «G. Mendel», Roma (Italia)

Summary

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The Authors describe the results obtained by their studies concerning the reaction of histocompatibility to homografts, the origin of parvicellular infiltration and regional lymphonodular modifications due to a skin graft.

The acceptance or reject of a homograft in rabbit twins makes it possible to establish the presence of MZ twins. As for the parvicellular infiltration, noticed in the case of kidney homografts, according to the researches of the Authors, who have depressed the graft by means of irradiation, it may be assumed that it is originated either from the graft, or from the host.

The study of regional lymph-nodes in the skin homograft in rabbit shows an evident proliferation of the lymphoreticular tissue starting in the very early days, when the graft is viable; in a subsequent stage corresponding to the graft's elimination there is a clear prevalence of plasmocytary elements in the lymphatic cords.

The homograft in mice of the inbred line C57 BL6 shows the graft's acceptance by tissural reactions equivalent to the ones of the autograft.

The homograft from random mouse on inbred mice shows the absence of a histiocytary lymphonodular reaction of the epithelioid type, which may be observed sometimes in the reaction to the allogenic homograft in the rabbit; it would be then a subsequent reaction not related to histocompatibility phenomena.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 12 , Issue 2 , April 1963 , pp. 97 - 116
Copyright
Copyright © The International Society for Twin Studies 1963

Footnotes

*

Relazione tenuta al «Simposio Internazionale sugli Omoinnesti», Università di Padova, 6-7-8 maggio 1963.

References

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