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Congenital Anomalies in Twins in Northern Ireland. I: Anomalies in General and Specific Anomalies Other Than Neural Tube Defects and of the Cardiovascular System, 1974–1979

Published online by Cambridge University Press:  01 August 2014

J. Little  and
N.C. Nevin
J. Little*
Affiliation:
Department of Comunity Medicine and Epidemiology, University of Notthingham, England
N.C. Nevin
Affiliation:
Department of Medical Genetics, Queen's University of Belfast, Northern Ireland
*
Department of Community Medicine and Epidemiology, The University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, UK

Abstract

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Data are presented from a large-scale population-based study in Northern Ireland, in which multiple sources of ascertainment were used. As found in other studies, the overall prevalence at birth of congenital anomalies amogst twins (285.4/10,000) was somewhat higher than the rate amongst singletons (241.8/10,000). Unlike in other studies, however, the rate amongst twins of like sex (287.8/10,000) was not markedly higher than that amongst twins of unlike sex (252.3/10,000). Problems of comparison between series are discussed.

Keywords

Congenital anomaliesTwinsAscertainmentDiscordanceGastrointestinal malformationsGenital malformationsSyndactylyDown syndrome
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 38 , Issue 1-2 , April 1989 , pp. 1 - 16
Copyright
Copyright © The International Society for Twin Studies 1989

References

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