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Congenital Anomalies in Twins in Aberdeen and Northeast Scotland

Published online by Cambridge University Press:  01 August 2014

G. Corney ,
I. MacGillivray ,
D.M. Campbell ,
B. Thompson  and
J. Little
G. Corney*
Affiliation:
M.R.C. Human Biochemical Genetics Unit, The Galton Laboratory, University College, London, England
I. MacGillivray
Affiliation:
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, Scotland
D.M. Campbell
Affiliation:
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, Scotland
B. Thompson
Affiliation:
M.R.C. Medical Sociology Unit, Institute of Medical Sociology, Aberdeen, Scotland
J. Little
Affiliation:
M.R.C. Medical Sociology Unit, Institute of Medical Sociology, Aberdeen, Scotland
*
The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, England

Abstract

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Data with regard to the proportion of congenital malformations found at birth are presented from a survey of 657 pairs of twins of known zygosity and placentation delivered in Aberdeen and Northeast Scotland between 1968 and 1979. There was an excess of malformed individuals from monozygotic (MZ) pairs, but this did not reach statistical significance. The possible effect of monochorionic placentation in the causation of malformations in MZ twins in general is discussed. It seems that this type of placentation may be of less causative importance than has been previously suggested.

Keywords

Congenital malformationsTwinsMonozygotic pairsMonochorionic placentation
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 32 , Issue 1 , January 1983 , pp. 31 - 35
Copyright
Copyright © The International Society for Twin Studies 1983

References

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