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Concordant Glaucoma in MZ Twins*

Published online by Cambridge University Press:  01 August 2014

L. Gedda ,
L. Scullica  and
A. Accardi
L. Gedda*
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Research, Rome Institute of Ophthalmology, University of Rome
L. Scullica
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Research, Rome Institute of Ophthalmology, University of Rome
A. Accardi
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Research, Rome Institute of Ophthalmology, University of Rome
*
Istituto di Genetica Medica e Gemellologia Gregorio Mendel, Piazza Galeno 5, 00161 Roma, Italy

Extract

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The Authors report a 54-year-old male MZ twin pair with two single-born relatives suffering from glaucoma.

The twins are concordant as to glaucoma, but onset of the disease in the first-born occurred 20 years later than in the second-born. This high chronological difference is ascribed to the hardships the latter twin had suffered for three years in Africa.

The meaning of anticipation is discussed in the light of modern views on the time dimensions of the unit of inheritance (chronon).

Type
Session 15 - Twins in Medical Genetics
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 19 , Issue 1-2 , April 1970 , pp. 268
Copyright
Copyright © The International Society for Twin Studies 1970

Footnotes

*

The full paper will be published on a forthcoming issue of this journal.

References

** Cf. Gedda, L., Brenci, G. (1969). Biology of the gene: the ergon/chronon system. Acta Genet. Med. Gemellol., 18: 329–379 CrossRefGoogle Scholar.