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Chromosomal and Dermatoglyphic Changes in Twins

Published online by Cambridge University Press:  01 August 2014

W. A. Yarema  and
D. S. Borgaonkar
W. A. Yarema*
Affiliation:
Division of Medical Genetics, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Md
D. S. Borgaonkar
Affiliation:
Division of Medical Genetics, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Md
*
St. Elizabeth Medical Center, 601 Miami Blwd. West, Dayton, Ohio 45408, USA

Summary

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A review of 15 chromosomally abnormal twin pairs indicates that finger and hallucal patterns of the affected twin are more similar to other patients than to the normal cotwin.

Correlation coefficients of TFRC and atd angle differences tend to remain similar in spite of the presence of chromosome abnormality in the cotwin. This supports the use of dermatoglyphic analysis as a means for diagnosing twin zygosity. Correlation coefficients of intrapair TFRC and atd angle differences in 25 control MZ twin pairs shows good agreement in zygosity determinations, when compared to results obtained by blood group and clinical observation studies.

In a series of 155 female and 142 male MZ twin pairs, TFRC and atd angle differences plotted on a graph against the frequency of occurrence illustrate that the range of variation is greater among females. Further study of a large series of twin pairs, however, is necessary to determine whether this is an effect of lyonization or the alteration of the polygenic complex of dermal configuration by the X chromosome.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 19 , Issue 3 , July 1970 , pp. 405 - 416
Copyright
Copyright © The International Society for Twin Studies 1970

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