A 24-year-study has been made of female quadruplets, two homozygous and two heterozygous, delivered by Cesarean section at 36 weeks gestation to a gravida 2 with severe preeclampsia and hydramnios. The babies were small for gestational age.

The development, management, education, and social environment are described. All are above average height, and physical and emotional problems have been few. The intelligence and education attainment of the first (also the smallest) baby are in the superior range, the others were high average. Two girls have married, one of whom has two normal sons.