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Balanced X; 22 Translocation in a Patient with Premature Ovarian Failure

Published online by Cambridge University Press:  01 August 2014

N. Banerjee ,
A. Kriplani ,
D. Takkar  and
K. Kucheria
N. Banerjee
Affiliation:
Department of Obstetrics and Gynaecology
A. Kriplani*
Affiliation:
Department of Obstetrics and Gynaecology
D. Takkar
Affiliation:
Department of Obstetrics and Gynaecology
K. Kucheria
Affiliation:
Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India
*
Addl. Prof. Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi – 110 029, India.

Abstract

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A case of balanced X; autosome translocation 46, X, t (X; 22) (q 24; q 13) in a 25-year-old female with secondary amenorrhea and premature ovarian failure (POF) is described. The relationship between balanced X; autosome translocation [t (X; A)] and varied phenotypic expression observed in these women is discussed. This case highlights the importance of early recognition of these women in order to give them the best chance of conception in their oligohypomenorrhic phase before complete loss of gonadal function.

Keywords

Ovarian failurePrematureX- chromosomeTranslocation – GeneticChromosome-Human pair – 22
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 46 , Issue 4 , October 1997 , pp. 241 - 244
Copyright
Copyright © The International Society for Twin Studies 1997

References

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