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Attempts to establish New Experimental Methods to study Antitumoral Drugs*

Published online by Cambridge University Press:  01 August 2014

S. Garattini ,
M. G. Donelli ,
L. Morasca ,
C. Rainisio  and
R. Rosso
S. Garattini
Affiliation:
Istituto di Ricerche Farmacologiche, « Mario Negri », Milano
M. G. Donelli
Affiliation:
Istituto di Ricerche Farmacologiche, « Mario Negri », Milano
L. Morasca
Affiliation:
Istituto di Ricerche Farmacologiche, « Mario Negri », Milano
C. Rainisio
Affiliation:
Istituto di Ricerche Farmacologiche, « Mario Negri », Milano
R. Rosso
Affiliation:
Istituto di Ricerche Farmacologiche, « Mario Negri », Milano

Summary

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This paper summarizes some studies recently carried out in this Institute in the field of cancer chemotherapy.

Three main groups of data are reported:

a) different sensitivity to chemotherapy of the same tumor transplanted in different sites of the body;

b) a method to study cancer dissemination as a basis for cancer chemotherapy;

c) a system to perfuse tissue culture with the blood of living animals as an approach to study duration of action of antitumoral drugs.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 17 , Issue 1 , January 1968 , pp. 60 - 66
Copyright
Copyright © The International Society for Twin Studies 1967

Footnotes

*

This work was supported by Euratom (Contract 040-65-1-BIOI) and by Consiglio Nazionale delle Ricerche (Contract 115/1134/1000).

References

Cliffton, E. E., Agostino, D. (1964). Effect of inhibitors of fibrinolytic enzymes on development of pulmonary metastases. J. Nat. Cancer Inst., 33: 753.CrossRefGoogle ScholarPubMed
Agostino, D., Cliffton, E. E. (1964). Anesthetic effect on pulmonary metastases in rats. Arch. Surg., 88: 735.Google Scholar
Fisher, E. R., Fisher, B. (1959). Experimental studies of factors influencing hepatic metastases. I. The effect of number of tumor cells injected and time of growth. Cancer, 12: 926.3.0.CO;2-0>CrossRefGoogle ScholarPubMed
Morasca, L., Rainisio, C. (1966 a). A method for perfusing tissue culture with an in vivo system. Experientia, 22: 337.CrossRefGoogle ScholarPubMed
Morasca, L., Rainisio, C. (19666). In Garattini, S., Sproston, E. M.: Antitumoral Effects of Vinca Rosea Alkaloids. Excerpta Medica International Congress Series, 106: 50.Google Scholar
Rosso, R., Palma, V. (1966). Chimiotherapie d'un nouveau type de tumeurs cérébrales. Franc. Etud. Clin. Biol., 11: 404.Google Scholar
Rosso, R., Palma, V. et al. (1966 a). A model for a cerebral tumor for studies in cancer chemotherapy. Experientia, 22: 62.CrossRefGoogle Scholar
Rosso, R., Palma, V. et al. (19666). An attempt to study cancer dissemination. Europ. J. Cancer, 2: 105.Google Scholar
Rosso, R., Palma, V. et al. (1967). Studies in cancer dissemination. Cancer Res., 27: 1225.Google Scholar