Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-23T01:22:42.885Z Has data issue: false hasContentIssue false

The «Accuracy» of estimates of MNS gene frequences

Published online by Cambridge University Press:  01 August 2014

William C. Boyd*
Affiliation:
Boston University - School of Medicine

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Wiener's methods for estimating gene frequencies from MNS data are compared with the maximum likelihood methods, and found not to be fully efficient. The extra effort and expense which would result from the use of such methods is discussed. It is concluded also that the number of significant figures advised by Wiener is not sufficient.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1956

References

1. Wiener, A. S. (1954). Serology, Genetics and Nomenclature of the M-N-S Types. Acta Genet. Med. Gemell. 3, 314.CrossRefGoogle Scholar
2. Boyd, W. C. (1953). Estimation of Gene Frequencies from MNS Data. Science 118, 756.Google Scholar
3. Boyd, W. C. (1954). Maximum Likelihood Method for Estimation of Gene Frequencies from MNS Data. Am. J. Hum. Gen. 6, 1.Google Scholar
4. Norton, H. W. (1954). Personal communication.Google Scholar
5. Boyd, W. C. (1954). Shortened Maximum Likelihood Estimation of Rh Gene Frequencies Am. J Hum. Gen. 6, 303.Google Scholar
6. Boyd, W. C. (1955). (Letter to the editor.) Am. J. Hum. Gen. 1, 447.Google Scholar
7. Kelley, T. L. (1947). Fundamentals of Statistics, Harvard University Press, Cambridge, Mass. Google Scholar
8. Fisher., R. A. (1950). Statistical Methods for Research. Workers. L1th edition. Oliver and Boyd, Edinburg.Google Scholar
9. Boyd, W. C. (1956). Am. J. Hum. Gen. 8, 24.Google Scholar
10. Fry, E. I. (1955). An Analysis of Cook Island Blood Groups. Paper presented at the 1955 meeting of the Am. Assoc. Phys. Anthrop. Google Scholar