This work discusses some aspects of the life of Luis de Carvajal, the head of the well-known Carvajal family. This man was Portuguese by birth, which meant that he was not allowed to go to the Spanish New World. Nevertheless, in 1579, Philip II awarded him a vast territorial entity in New Spain, called Nuevo Reino de León, and allowed him to bring to it a large number of people without having to certify their being Old Christians. Nearly ten years later, he was apprehended by orders of Viceroy Manrique de Zuñiga and brought to Mexico City, where he was jailed in the Crown's prison. On April 14, 1589, he was transferred to the secret jails of the Spanish Inquisition, where he was subjected to a nine-month-long trial, accused of heresy, of knowingly bringing Jews to New Spain, and of concealing their religious activities. Ultimately, he was found guilty of the last two charges and was sentenced to a six-year exile from New Spain. However, before the sentence was carried out, he was returned to the Crown's jail, where he died a year later.